Hedysari polysaccharide (HPS) is the main component of hedysarum polybotrys. HPS can inhibit tumor cell proliferation, block the cell cycle in the G2-M period, modulate apoptosis via the mitochon drial pathway, and improve the red blood cell innate immunity and T lymphocyte immune function. HPS can relieve low immunity caused by chemotherapeutics.HPS plays anti-tumor effects by these ways mentioned above.

Objective To analyze the data of concentric (c) and eccentric (e) peak torque of hamstring (H) and quadricep (Q) in differ-ent gender and angle after 4-week concentric and eccentric isokinetic exercise training on knee, in order to provide suggestions for the knee extensor and flexor in rehabilitation exercise prescription. Methods 28 healthy college students from May to June 2014 in our college partic-ipated in maximum concentric (n=14) or eccentric (n=14) resistance training of the right knee extensors and flexors 3 times per week for 4 weeks. The concentric strength was measured with BIODEX isokinetic dynamometer assessment system 4 at 30 °/s, 60 °/s, 90 °/s, and ec-centric strength was measured at 60 °/s, 120 °/s, 180 °/s. PT, H/Q (He/Qc, Hc/Qc) ratio and H/H (He/Hc) or Q/Q(Qe/Qc) ratio were ana-lyzed. Results Concentric isokinetic training could improve the Hc and He at 60 °/s and 90 °/s (P<0.05), and the Qe and Qc increased at 30 °/s, 60 °/s, 90 °/s respectively (P<0.01). There was no significant improvement after eccentric training (P>0.05). After concentric isokinet-ic training, the He/Qc ratio decreased at 90 °/s (P<0.05), the Hc/Qc ratio decreased at 30 °/s (P<0.05). However, there was no difference in He/Qc and Hc/Qc after eccentric contraction (P>0.05). The Qc/Qe ratio increased at 60 °/s and 90 °/s (P<0.05), and the Hc/He ratio de-creased at 90 °/s (P<0.05) after concentric training. There was no difference in Hc/He and Qc/Qe after eccentric contraction (P>0.05). There were significant differences in Hc, He, Qc, Qe and He/Qc ratio between different genders (P<0.05). Conclusion Concentric training and ec-centric training have different influences on the muscle strength after 4 weeks training. Eccentric training only can reduce the knee stability. Hc/He ratio and Qc/Qe ratio can be used to evaluate the knee muscle function. Gender should be considered into training.

The strain Streptomyces sp.,nominated IMB-14,was isolated from the soil sample of WuDang Mountain by the method of cellulose ester membrane filter.The studies on antibiotic activities,morphological characteristics,cultural characteristics,physiological characteristics,16S rDNA sequence analysis and the metabolite of strain IMB-14 showed that the strain IMB-14 was accordance with Streptomyces xanthoci-dicus.The study on the isolation and identification of strain Streptomyces xanthocidicus establishes a foundation on screening of novel antibacterial and antitumor agents.

0.05),but the proportion of NRDS,the rate of mechanical ventilation dependence,and mortality had significant diffe-rences(Pa

The apoptosis of cardiac muscle cells refers to an initiative cell death process that is controlled by a series of genes, and in fact it is a kind of physiological cell death. The authors of this article reviewed and analyzed the biology characteristics and development mechanisms of the apoptosis of cardiac muscle cells, summarized the research progress of the apoptosis of cardiac muscle cells and exercise, so as to offer theoretical reference for exercise training and heart protecting.

Aged ; Cavernous Sinus ; Humans ; Leukemia, Myeloid, Acute ; drug therapy ; Male ; Syndrome

Adult ; Aged ; Airway Management ; Cyanides ; poisoning ; Female ; Humans ; Male ; Middle Aged ; Poisoning ; nursing ; Young Adult

PurposeSpinal cord is one of the most frequently involved sites of multiple sclerosis (MS), which seriously affects the life quality of patients. In this paper, we investigate the application value of voxel-based morphology (VBM) and resting-state magnetic resonance imaging (RS-fMRI) in multiple sclerosis patients with single spinal cord involvement (MS-SSCI).Materials and Methods Three-dimensional T1WI data and RS-fMRI data were acquired from 20 patients with MS-SSCI and 20 normal controls, grey matter volume (GMV), changes of white matter volume (WMV), total intracranial volume (TIV) and local nuclei volume were compared between the two groups using VBM, posterior cingulate cortex (PCC) was regarded as the seed point and the functional connectivity about whole brain was compared between the two groups by using resting-state functional connectivity analysis, the relationships between MS-SSCI structure, function change parameters and expanded disability states scale (EDSS) scores were further explored.Results①Compared with the control group, GMV, WMV, TIV of MS-SSCI group were not significantly reduced, only the volume of some regions (bilateral middle temporal gyrus, left inferior temporal gyrus) showed significant atrophy (P<0.01); MS-SSCI exhibited increased functional connectivity (FC) in the left medial prefrontal cortex, left inferior temporal gyrus, left caudate nucleus and right supplementary motor area (two-sample t test, after AlphaSim correction,P<0.01, voxel size >40).②There was no significant correlation (P>0.05) between MS-SSCI structure change parameters and EDSS; while a significant correlation between EDSS scores and FC was noted in the left inferior temporal gyrus (r=0.633,P<0.05).Conclusion Both structural abnormalities and altered FC with PCC can be detected in MS-SSCI, but only functional parameters are associated with clinical abnormalities, which are more sensitive than microstructural changes.

Objective:To observe different effects of moxibustion at Zusanli (ST 36) and Yanglingquan (GB 34) on electrogastrogram (EGG) of patients with functional dyspepsia (FD). Methods:A total of 65 cases were randomized into a Zusanli (ST 36) group (n=33) and a Yanglingquan (GB 34) group (n=32) by random serial number, to receive moxibustion therapy to the corresponding point respectively. The 8-lead EGG was used before and after treatment to collect EGG parameter of the gastric body, antrum of stomach, lesser curvature and greater curvature, including the dominant frequency, slow wave percentage, average frequency, response area and motility index. Results:After treatment, the dominant frequency and slow wave percentage were improved in nearly the whole stomach area in Zusanli (ST 36) group, showing statistical significances (bothP<0.05); the slow wave percentage and average frequency were improved in stomach body and antrum of stomach in Yanglingquan (GB 34) group, showing statistical significances (bothP<0.05); moxibustion at Zusanli (ST 36) had a significantly higher influence on EGG than Yanglingquan (GB 34) , in which the lifting of slow wave percentage was significantly higher than Yanglingquan (GB 34) group (P<0.05). Conclusion: Moxibustion at Zusanli (ST 36) and Yanglingquan (GB 34) has the effect of adjusting abnormal EGG pattern in FD patients. Compared with Yanglingquan (GB 34), Zusanli (ST 36) has a superior effect in improving EGG in stomach area.

Objective To analyze MRI features of breast intraductal papilloma,to improve the acquaintance of this disease.Methods The preoperative MRI images (T2 WI-SPAIR,DWI,ADC,TIC and MIP)of eight patients with breast intraductal papilloma confirmed by surgery were reviewed retrospectively,which were compared with the postoperative pathology.The morphology,distribution, enhanced methods and signal characteristics of the lesion were summarized.Results Of 8 cases,the lession was dormant,and MRI revealed three patterns:the first type was occult papilloma,which presented distention of ducts and no solid nodule in 3 cases (37.5%);the second type showed tiny nodules in bar-like dilatation of ducts in 3 cases (37.5%);and the third type presented small round nodules scattering distribued in terminal ductules in 2 cases (25%).The maximum diameter of nodular lesions was 0.4-1.0 cm(average 0.7 cm).The lesions on T2 WI-SPAIR showed equal signal intensity or mixed signals with isointensity/hypointensity,and dilatation catheter.enhancement. The ADC and TIC value were various,therefore,diagnosis of the tumor should be combined with morphology and associated symptoms. Conclusion At early stage,the occult focus of breast intraductal papilloma can be sensitively detected and localized on MRI.It reveals that MRI has advantage in showing morphology of lesion and functional imaging,which is of important value in clinical diagnosis and early treatment.