The paper was designed to consider the effect of vitamin E on metabolism of cyclic nucleotide in cold exposed male rats. The urinary excretion of cyclic nucleotide was investigated by radioimmunoassay after male rats treated with vitamin E in 4℃ exposure. The results showed that urinary excretion of cyclic nucleotide had been increasing and cAMP/cGMP ratio had been not changing in cold exposed male rats. When one week of the experiment vitmin E could increase urinary cAMP excretion more in its treated group than cold exposed group alone (P

Objective:To study the relationship between MMPs and the metastasis and the malignant degree of tumors in children.Methods:The expression of MMPs in different tumor groups was measured by means of immuno-histochemistry.Results:The expressions of MMP-3 in cytoplasm of tumor cells were observed.There was significant difference( P

Animals ; Antigens, Neoplasm ; genetics ; metabolism ; Biomarkers, Tumor ; genetics ; metabolism ; Brain Neoplasms ; metabolism ; Cell Adhesion Molecules ; genetics ; metabolism ; Digestive System Neoplasms ; metabolism ; Female ; Genital Neoplasms, Female ; metabolism ; Glioma ; metabolism ; Head and Neck Neoplasms ; metabolism ; Humans ; Immunotherapy ; Male ; Prostatic Neoplasms ; metabolism ; Signal Transduction

Animals ; Diagnosis, Differential ; Humans ; Idiopathic Interstitial Pneumonias ; pathology ; Lung ; diagnostic imaging ; pathology ; Lung Diseases, Interstitial ; classification ; pathology ; Pulmonary Fibrosis ; pathology ; Tomography, X-Ray Computed

Crisis Intervention ; Disasters ; Humans ; Stress, Psychological ; prevention & control

China ; Humans ; Mental Health ; Public Health Practice

Brain ; metabolism ; Brain Chemistry ; Creatine ; deficiency ; Humans ; Syndrome

Adenine ; analogs & derivatives ; therapeutic use ; Antiretroviral Therapy, Highly Active ; methods ; HIV Infections ; drug therapy ; prevention & control ; Hepatitis B, Chronic ; complications ; Hepatitis C, Chronic ; complications ; Humans ; Lamivudine ; therapeutic use ; Organophosphonates ; therapeutic use

Objective To investigate the changes and clinical signficance of nitric oxide(NO) and endothelin(ET) in children with lymphoma.Methods NO and ET of 39 cases with lymphoma and 33 normal controls were examined by using nitrose reductase method and RIA method.Results Compered to normal controls,NO and ET were higher in children with lymphoma;smilar to normal controls in complete remission(CR) and partial remission(PR);relapse cases were higher than remission.Conclusions NO and ET could have relation to lymphoma in children,testing the changes of NO and ET have signficanc to the assistant diagnosis,observeing effect and judging prognosis.

Objective To investigate the effects of DNaseⅠ-treated streptococcal antigens on peripheral blood mononuclear cells(PBMC)proliferation in psoriasis patients.Methods PBMC from 15 patients with psoriasis and 10 healthy controls were stimulated with three concentrations(2,10,25?g/mL) of streptococcal antigens(SA), nd DNaseⅠ-treated streptococcal antigens(DNaseⅠ-SA).After 72 h of culture,cellular proliferation was determined by ~3H thymidine incorporation.Results The DNaseⅠ-SA,at all the concentrations tested,was less potent than the corresponding concentrations of SA(P0.05),however,the lower concentrations(2,10?g/mL) of DNaseⅠ-SA were less potent than those of SA(P0.05).Also,the extent of proliferation response to SA and DNaseⅠ-SA was higher in the patients than in the controls(P