1.User Security Authentication System for Campus Network
Yi ZHANG ; Donghuai GAO ; Weizhong XU ; Hao XU
Chinese Medical Equipment Journal 1989;0(04):-
Objective To introduce and analyze the current user security authentication system in the campus network and point out the secure problems and hidden dangers of the correspondence entities in the campus network. Methods The authentication technologies and protocols in the TCP/IP network model were compared. It was proposed that the campus network security authentication solution should include access control in data link layer, connection control in network layer and unified authentication in application layer. Results The solution could improve the campus network authentication security rank. Conclusion The security and reliability of the network system are enhanced.
2.Effects of dioxins on immune and endocrine systems
Hao DENG ; Song YI ; Zhaofa XU ; Jiaqing SHAO
Journal of Medical Postgraduates 2004;0(01):-
Dioxin,one of the persistent organic pollutants,persistently exists in the environment and does serious harm to the ecological environment as well as to the human body because of its reproductive toxicity,carcinogenicity,immune toxicity,skin toxicity and toxicity to other systems and organs.This paper reviewed the toxicities of dioxins to the human body,especially to the endocrine and immune systems.
5.Pharmacokinetic comparison of roxithromycin under normoxic and hypoxic conditions in rats by UPLC/MS/MS
Tao SHAO ; Yi QIN ; Pingxiang XU ; Weizhe XU ; Liang ZHAO ; Yi MA ; Weijia HAO ; Ming XUE
Chinese Pharmacological Bulletin 2016;32(11):1596-1600,1601
Aim To study and compare the pharmaco-kinetic parameters of roxithromycin under normoxic and hypoxic rats. Methods A highly effective and rapid ultra-performance liquid chromatography with tandem mass spectrometry ( UPLC-MS/MS) method with posi-tive electrospray ionization source was successfully de-veloped and validated for quantification of roxithromy-cin in rat plasma. Sprague-Dawley rats were randomly divided into the hypoxia and normoxic groups. Each rat obtained a single dose of roxithromycin with 10 mg · kg-1 via intragastric administration. The pharmacoki-netic parameter comparison between normoxic and hy-poxic groups was calculated by SPSS software using in-dependent sample t test method. Results The main pharmacokinetic parameters of roxithromycin between the normoxic and hypoxic rats were:the AUC(0-t) 7 576 and 3 761 μg·h·L-1 , MRT(0-t) 5. 6 and 7. 7 h, T1/2 3. 4 h and 3. 9 h, CL 1. 5 and 3. 0 L · h-1 · kg-2 , tmax3. 1 and 3. 4 h, Cmax 1 116 and 372 μg·L-1 , re-spectively. The levels of Cmax and AUC of roxithromy-cin in hypoxic rats were statistically lower than those in normoxic rats. Conclusion The exposure level of rox-ithromycin in hypoxic rats markedly decreased. Our re-sults may provide an important experimental basis to adjust the dosage for roxithromycin in hypoxic clinical practice.
6.Solidification of volatile oil with graphene oxide.
Hong-Mei YAN ; Xiao-Bin JIA ; Zhen-Hai ZHANG ; E SUN ; Yi-Hao XU
Acta Pharmaceutica Sinica 2015;50(2):222-226
To evaluate the properties of solidifying volatile oil with graphene oxide, clove oil and zedoary turmeric oil were solidified by graphene oxide. The amount of graphene oxide was optimized with the eugenol yield and curcumol yield as criteria. Curing powder was characterized by differential scanning calorimetry (DSC) and scanning electron microscopy (SEM). The effects of graphene oxide on dissolution in vitro and thermal stability of active components were studied. The optimum solidification ratio of graphene oxide to volatile oil was 1:1. Dissolution rate of active components had rare influence while their thermal stability improved after volatile oil was solidified. Solidifying herbal volatile oil with graphene oxide deserves further study.
Calorimetry, Differential Scanning
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Clove Oil
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chemistry
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Curcuma
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chemistry
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Eugenol
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Graphite
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chemistry
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Microscopy, Electron, Scanning
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Oils, Volatile
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chemistry
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Oxides
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chemistry
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Plant Extracts
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chemistry
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Powders
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Sesquiterpenes
7.Clinical observation of the disto-lingual root of the impacted mandibular third molars
Hao LI ; Biao YI ; Qing LI ; Lidong ZOU ; Weihua XU ; Zhi WANG
Journal of Practical Stomatology 2014;(4):564-565
Cone beam CT(CBCT)data of 4 550 impacted mandibular third molars were divided into 6 groups by the direction of teeth im-paction.Analyzed by SPSS 19.0 statistical package and Pearson Chi-square Test,the incidence of disto-lingual roots was 5.38% and was various with different impation direction.
8.Super-minimally invasive bilateral thoracoscopic extended thymectomy
Wei WANG ; Dazhong LIU ; Hao XU ; Yi LI ; Lei YANG ; Linyou ZHANG
Chinese Journal of Thoracic and Cardiovascular Surgery 2017;33(3):135-136
Objective To present the technique of super-minimally invasive bilateral thoracoscopic extended thymectomy,and evaluate the early clinical results by using of this technique.Methods Twenty-three patients with myasthenia gravis (MG) with thymoma underwent with super-minimally invasive bilateral thoracoscopic extended thymectomy in our institution between July 2014 and January 2016.Two operate-poles are 5mm trocar,one is three intercostal space at the anterior axillary line,and the other is four intercostal space at the midclavicular line.A 10 mm trocar is inserted through the 6th intercostal space in the mid axillary line.The perioperative variables and outcomes were collected and analysed retrospectively.Results In the 23 patients who underwent Super-Minimally invasive bilateral thoracoscopic extended thymectomy,the mean operation time was (163.2 ± 14.4) min and the average blood loss was (148.2 ± 39.5) ml.The chest tube duration was (4.14 ± 0.27) days.There were no mortalities.Conclusion Our preliminary report showed that Super-Minimally invasive bilateral thoracoscopic extended thymectomy for mediastinal tumour resection was a promising and safe technique with regard to short-term clinical outcome.
9.Observation on the Clinic Effect of r-MHT and Hematoma Aspiration on the Traumatic Intracerebral Hematoma
Hao CHENG ; Changlin XU ; Congguo LIU ; Sheng CHEN ; Na LIU ; Yi LI ; Fangran WANG ; Zhenliang LI
Progress in Modern Biomedicine 2017;17(23):4518-4520
Objective:To investigate the clinic effect of r-MHT and hematoma aspiration on the traumatic intracerebral hematoma.Methods:89 cases with traumatic intracerebral hematoma were given hematoma aspiration,47 of them were given r-MHT and hematoma aspiration,the clinic effect on the 1st,7th,14th day after treatment were evaluated by NIHSS,the hematoma volume before treatment on the 1st,7th,14th day after treatment were counted by Dotian formula.Results:The effective rate of treatment group was 93.6%,which was significantly higher than that of the control group (P<0.05).The NIHSS score of treatment group was significantly higher than that of the control group(P<0.05) on the 1 st day,1st,2nd week after treatment (P<0.05).Conclusion:r-MHT and hematoma aspiration couldn effectively reduce the brain damage,improve the patient's neurological fumction in treating traumatic intracerebral hematoma.
10.Therapeutic response of radiosynovectomy with ~(32)P colloid in haemophilic synovitis of adolescents
lei, JIANG ; pei-yong, LI ; ping, HAO ; yi-fan, ZHANG ; xu-feng, JIANG ; su-yun, CHEN
Journal of Shanghai Jiaotong University(Medical Science) 2006;0(11):-
Objective To evaluate the efficacy of radiosynovectomy with 32P colloid in haemophilic synovitis of adolescents. MethodsRadiosynovectomy with 32P colloid was primary performed on 26 male haemophilic patients(26 joints),whose average age was 16 years(11 to 21 years).The average dose of 32P colloid was 2.1 mCi(1.0 to 3.0 mCi). Results After 6-month interval,haemarthrosis was reduced by no less than 30% in 23 patients,with a total efficacy of 88.5%.The mean frequency of haemarthrosis was reduced from 1.9 per month of presynovectomy to 0.3 per month of postsynovectomy(P