1.Clinical effect of Wuling Capsule on senile systolic hypertension with anxiety
Chinese Traditional Patent Medicine 1992;0(10):-
AIM:To evaluate the efficacy of Wuling Capsule(xylaria) in treating senile systolic hypertension. METHODS: Sixty-four patients with senile systolic hypertension were randomly divided into two groups.Both the treated group and the control group were treated with anti-hypertensive for 4 weeks,but the treated group received Wuling Capsule.Therapentic effects were evaluated with HAMA.Noninvasive resting blood pressure was taken every day after treatment,and dynamic blood pressure before and after treatment. RESULTS: HAMA in both groups decreased somewhat but blood pressure in the treated group was lower than that in the control group,remission rate of the treated group was greater than that in the control group.Treatment period of the treated group was shorter than that of the control group. CONCLUSION: Wuling Capsule can relief anxiety in senile hypertension patients,and it can rise the control rate of blood pressure,and also shorten the treatment period.
2.Effect of MDG-1, a polysaccharide from Ophiopogon japonicas, on diversity of lactobacillus in diet-induced obese mice.
Lin-lin SHI ; Yuan WANG ; Yi FENG
China Journal of Chinese Materia Medica 2015;40(4):716-721
For understanding the effect of MDG-1, a water-soluble β-D-fructan polysaccharide from Ophiopogon japonicas, on intestinal microecological balance, especially on the changes of lactobacillus, sixty 8-week-old male C57BL/6J mice were given a high-fat diet for six weeks and were also gavaged with saline once a day simultaneously. Then the mice which is below 30 grams or dropped more than 10% through lavage were eliminated and the rest were randomly divided into four groups: diet-induced obese (DIO) model group (n = 12, gavaged with saline), low-dose MDG-1 group (n = 12, gavaged with MDG-1, 75 mg · kg(-1)) , medial-dose MDG- 1 group (n = 12, gavaged with 150 mg · kg(-1)), and high-dose MDG-1 group (n = 12, gavaged with 300 mg · kg(-1)) according to the weight and blood glucose; the model group and MDG-1 group were placed on a high-fat diet while the normal control group (n = 12, gavaged with saline) were kept on a low-fat diet through the experiment. After 12-weeks of treatment, feces samples were collected and cultured for intestinal microecological balance analysis. Then the intestinal probiotics were cultured through traditional methods combined with modified gradient gel electrophoresis (DGGE) method. The changes of lactobacillus in each treatment group were also detected by a statistical analysis of the total number of the intestinal flora. We have established the phylogenetic tree by 16S rDNA sequencing and use some molecular identification methods such as PCR-DGGE to analyse the changes of the dominant bacteria floras, and also get the pure culture. In conclusion, different concentrations of MDG-1 can increase the number of the intestinal probiotics, especially Taiwan lactobacillus and Lactobacillus murinus, and improve their diversity and promote proliferation in a dose-dependent way.
Animals
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Biodiversity
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Diet, High-Fat
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adverse effects
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Dietary Carbohydrates
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administration & dosage
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analysis
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Humans
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Intestines
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drug effects
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metabolism
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microbiology
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Lactobacillus
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classification
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drug effects
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genetics
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growth & development
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Male
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Mice
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Mice, Inbred C57BL
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Mice, Obese
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Molecular Structure
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Obesity
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drug therapy
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metabolism
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microbiology
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Ophiopogon
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chemistry
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Phylogeny
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Plant Extracts
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administration & dosage
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chemistry
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Polysaccharides
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administration & dosage
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chemistry
4.Effect of individualized diet nursing on nasogastric feeding-induced complications after operation on laryngeal cancer
Yi LIN ; Feng LI ; Weili YANG
Modern Clinical Nursing 2013;(5):40-42
Objective To evaluate the effect of individualized diet nursing on nasogastric gavage-indueced complications after operations on laryngeal cancer? Methods Sixty patients having undergone surgical operation on laryngeal cancer were randomly divided into experiment group and control group in equal number? The control group received nutritional support by conventional enteral nutrition and the experiment group was managed by individualized diet nursing with nasogastric feeding? On days 3 and 10 after operation,the two groups were compared in terms of body constitution,results of experimental tests and complications?Result Compared to the control group,the experiment group showed no significant difference in terms of body constitution and results of experimental tests(P > 0?05)but significantly lower rate of complications on days 3 and 10(P < 0?05)? Conclusion The individualized diet nursing for laryngeal cancer patients may ensure their needs for nutrition,meanwhile reduce the incidences of complications from enteral nutrition,and thus promote their recovery?
5.Application of robotic system in gastrointestinal surgery.
Xin-Yu QIN ; Feng-Lin LIU ; Yi-Hong SUN
Chinese Journal of Gastrointestinal Surgery 2011;14(5):311-313
Robotic system helps surgeons in performing surgery. Currently Da Vinci system is the most popular. Da Vinci system has been used for the stomach and bowel diseases in 27 cases(18 cases of stomach and 9 cases of colon and rectum) in the Zhongshan Hospital, Fudan University. Accurate preoperative staging is crucial, and Da Vinci system is advantageous in lymph node dissection, preservation of nerve plexus, and complete resection of mesorectum. Adoption of gastrointestinal tract reconstruction technique should depend on the operation and experience in surgery. Though Da Vinci system has limitations and the cost is high, it is believed to be the future trend.
Digestive System Surgical Procedures
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methods
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Humans
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Robotics
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methods
6.The feasibility of segmental method in testing human balance control with a three dimensional motion analysis system
Yi ZHU ; Tong WANG ; Dian-Huai MENG ; Feng LIN ;
Chinese Journal of Physical Medicine and Rehabilitation 2003;0(09):-
Objective To investigate the reliability and sensitivity of a three dimensional motion analysis system by using the segmental method.Methods Ten healthy young men participated in this study.They were asked to stand with one leg and with their eyes open and closed,respectively,each lasted for 30 seconds and was re- peated twice.According to the 12-segment rigid body model of the human body,twenty-one infrared light emitting di- ode(1RED)markers were placed over the bony prominences on the proximal and distal ends of each segment,the motion track of the IRED markers was recorded by the three dimensional motion analysis system.The mean sway am- plitude( MSA )and the sway path(SP)of the center of gravity(COG)were calculated.Correlation analysis was used to determine the reliability between the two repetitions.Paired sample t-test was used to determine the sensitivity be- tween the eyes open and closed conditions.Results The correlation coefficients of the MSA of the COG in the eyes open and closed conditions were 0.623 and 0.018,respectively,and the correlation coefficients of the SP of the COG were 0.936 and 0.654,respectively.It was also shown that significant differences existed among the three directions of the MSA of the COG and the SP of the COG.Conclusion Besides the weak reliability of the MSA of COG in the eyes closed condition,the high reliability and sensitivity of the MSA and SP of the COG are found.The segmental method can be used in the scientific study of human balance control.
8.Quality evaluation system for the oral sustained- and controlled-release drug delivery systems of traditional Chinese medicine.
Yuanfeng WEI ; Xiao LIN ; Ning ZHANG ; Yi FENG
Acta Pharmaceutica Sinica 2010;45(4):430-5
Oral sustained- and controlled-release drug delivery systems of traditional Chinese medicine (TCM) are a research hotspot in the development of drug-delivery systems for TCM. The quality evaluation system is an important guarantee for the safety and efficiency of these drug-delivery systems. In this paper the methods to construct such quality evaluation system were discussed.
9.Adherence activity of periodontal pathogens and cariogenic bacteria to hydroxyapatite disks
min-feng, WANG ; de-yi, LI ; zong-lin, LI
Journal of Shanghai Jiaotong University(Medical Science) 2006;0(01):-
Pg.The adherence activity of periodontal pathogens to HA was enhanced by Ss and Av.When cultivated with Sm,the adherence activity of Pg was reduced.Periodontal pathogens had no effect on the adherence activity of Sm and Av,and Ss excepted. Conclusion The adherence activity of periodontal pathogens is lower than that of cariogenic bacteria.Periodontal pathogens can utilize early-attached bacteria to become those predominant bacteria in periodontal ecosystem.
10.A prospective study to assess cardiac function of valve disease in elderly patients with hypertension by echocardiography
He-lin, ZHANG ; Ya-feng, WU ; Yi-dan, LI
Chinese Journal of Medical Ultrasound (Electronic Edition) 2010;07(12):2095-2100
Objective To investigate the change of cardiac function in elderly hypertensive patients with heart valve degenerative by echocardiography.Methods A total of 126 cases were divided into a valve disease group and non-valve disease group groups.The parameters of trial size,cardiac function and pulmonary artery pressure were detected.Results Of all 126 cases were the patients with hypertension including 28.6% (36/126) of valve disease group and 71.4% (90/126) of non-valve disease.There were 31 cases with mitral valve disease,22 cases with tricuspid valve disease; 26 cases with aortic valve disease; 36 cases with double or three alvular lesions in valve disease group.There was a significant difference in ventricle size and systolic function among valve disease group and non-valve disease group and control group.But there was no significant difference in thickness of ventricular wall between valve disease group and non-valve disease group.Conclusion The elderly hypertensive patient with valve disease was an independent factor for the development of congestive heart failure.