1.The organization of stand-by UN peacekeeping Chinese medical contingent
Journal of Medical Postgraduates 2003;0(07):-
The organization of Stand-by UN Peace-keeping Medical Contingent in PLA is at its Primary Stage.By Combining the Organization Practice of UN Peace-keeping Chinese Medical Contingent with the Draft MOU and Reality in our Army,The Authors Deeply Studied the Organization Plan,including the Mobilization,criteria for the candidates,and Medical Standards et al.
2.Impact of different blood glucose levels in gestational diabetes mellitus on maternal and neonatal outcomes
Journal of Chongqing Medical University 1987;0(01):-
Objective:To evaluate the impact of different glucose levels in women with gestational diabetes mellitus on maternal and neonatal outcomes.Methods:Data of 65 pregnant women with GDM admitted in our hospital from January 2001 to October 2006 were reviewed.A total of 46 GDM women had blood glucose levels under control before delivery and the rest 19 GDM women did not.The impact of different glucose levels on maternal and neonatal outcomes were compared between the two groups.Results:In the group with the glucose level uncontrolled,the incidence of hypertensive disorder complicating pregnancy,premature rupture of membrane,hydramnios,postpartum hemorrhage,premature infant,neonatal asphyxia,fetal macrosomia,and therapy after 34 weeks pregnancy were 42.11%,26.32%,31.58%,21.05%,47.37%,15.79%,36.84%,and 57.89%,respectively.compared with those of the group with glucose level controlled as 15.22%,4.35%,6.52%,2.17%,17.39%,0.00%,10.87%,and 28.26%,respectively.All the rates of the uncontrolled group were markedly higher than those of the controlled group.Conclusion:Gestational diabetes mellitus does great harm to mother and infant.Diagnosing GDM and controlling blood glucose as early as possible can decrease the complications of mother and infant.
3.Application of gabapentin in the treatment of neuropathic pain
International Journal of Cerebrovascular Diseases 2015;23(11):859-862
As an anti-epilepsy drug,gabapentin plays an important role in the treatment of neuropathic pain through a variety of central and peripheral mechanisms.Studies have shown that gabapentin has better efficacy for post-stroke pain,spinal cord injury-related pain,postherpetic neuralgia,and pain in diabetic peripheral neuropathy.For mild adverse effects,good tolerance and lack of interactions,gabapentin is an ideal drug for the treatment of neuropathic pain.
4.A study on visual P300 evoked by facial expression stimulus in social anxiety disorder
Chinese Journal of Behavioral Medicine and Brain Science 2010;19(11):972-974
Objective To explore the changing indications of visual P300 evoked by facial expression stimulus in social anxiety disorder (SAD). Methods 30 patients with SAD were consecutively recruited, and matched with 30 normal controls (NC). They were evaluated by self-designed demographic questionnaire and Liebowitz Social Anxiety Scale (LSAS), Meanwhile the examination of the visual P300 evoked by five facial expression stimulus included sad, happy, surprise, angry and disgust was administrated to SAD patients and normal controls. Results Compared with NC group, SAD group had higher target P2 amplitudes ( ( 3.73 ± 3.06 ) μV )and higher target P3 amplitudes( ( 9.43 ± 4.01 ) μV ) evoked by angry facial expression (P< 0.05 ) and higher target P3 amplitudes( (9.57 ±4.42) μV) evoked by disgust facial expression (P<0.05). The scores of LSAS in SAD was positively correlated with target P2 amplitudes (P<0.05). Conclusion SAD group has abnormal changing indications of visual P300 evoked by facial expression stimulus.
6.Capillary Electrophoresis of Neurotransmitters Under the Control of Radial Electric Field
Chinese Journal of Analytical Chemistry 2001;29(6):661-663
Separations of neurotransmitters such as dopamine (DA), ser otonin (5-HA), norepinephrine (NE) and epinephrine (E) were performed successf ully using a homemade electric field modulated capillary electrophoretic system, which could offer both radial and axial electric fields with only one high volt age power supply. DA and 5-HT were eluted simulaneously and could not be resolv ed in 0.01 mol/L phosphate buffer at pH 2.5. Alcohol additives, such as methanol , ethanol or 1-propanol were added to the buffer to change the solvation shell of the solutes, which changed their effective sizes and electrophoretic mobiliti es of the solutes accordingly. The optimum composition was a buffer of 20% (V /V) 1-propanol, with resulted resolutions 0.74 (DA/5-HT), 0.56(5-HT/NE) and 0.77 (NE/E). If a positive radial voltage of 6.6 kV was applied, the resolut ions were improved to 1.48, 0.71 and 1.32, respectively.
7.Antiviral treatment status and progress of chronic hepatitis C in children
Chinese Journal of Applied Clinical Pediatrics 2017;32(10):727-729
Children with hepatitis C virus RNA positive were considered to start antiviral treatment.Alpha interferon or pegylated interferon plus ribavirin in children achieved satisfactory sustain virology response.Although there were many adverse events,some can be relieved by communicating with the guardian,bringing care to the patient and giving treatment.Clinical trials in children with hepatitis C by the direct-acting antiviral agents were in progress,safety and efficacy have no differences with the adult.There were still lots of work to do in view of the particularity of children.
8.Heart rate variability in ischemic stroke: evaluation method and clinical significance
International Journal of Cerebrovascular Diseases 2015;23(10):781-784
Autonomic nerve dysfunction is common after onset of ischemic stroke.Heart rate variability (HRV) has been used widely because of the regulation effect of heart rate by the quantitative analysis of the autonomic nervous system.This article reviews the evaluation method of HRV and its clinical significance in ischemic stroke.
9.Some guidelines on medical service projects of Chinese peacekeeping medical contingent
Journal of Medical Postgraduates 2003;0(09):-
UN medical service aims at setting up standards applying to peacekeeping operations, which is also in line with usual medical care system. Based on full apprehension of UN medical service guidelines and its system, Chinese Medical Contingent made a comprehensive analysis of all factors affecting medical support, and established a series of medical service projects with consideration of the characteristics of Chinese Armies.
10.AMPK and metabolic syndrome
Basic & Clinical Medicine 2006;0(01):-
Imbalance of energy metabolism is a major cause for metabolic syndrome. AMP-activated protein kinase AMPK is a central component of a protein kinase cascade that plays a pivotal role in the regulation of intracellular energy status.AMPK activity is a response to the ratio of AMP/ATP in the cell.When a stress causes an inhibition of ATP production or an increase of ATP consumption,cellular AMP/ATP ratio increases,AMPK is activated.Once activated,AMPK initiates a series of responses to restore the energy balance within the cell.AMPK switches on catabolic pathways,such as fatty acid oxidation and glycolysis,to generate ATP,and switches off anabolic pathways,such as fatty acid synthesis and protein synthesis,to reduce ATP-consumption.Therefore,AMPK functions in an ideal position not only as an energy sensor at cellular level,but also as a pivotal player in the regulating pathways that control both energy expenditure and energy intake,in particular by mediating the effects of hormones and cytokines such as leptin,adiponectin and ghrelin.The recent finding that anti-diabetic drug metformin and TZD regulates glucose metabolism through the activation of AMPK suggested a possible role of AMPK in protecting the body from metabolic diseases such as metabolic syndrome,obesity and type 2 diabetes.Thus,further work in this field in the next several years will be necessary in order to fullyunderstand the role of AMPK in regulating the balance of energy storage and expenditure in different tissues and at the whole body level.Targeting to AMPK cascade would also have potentially pharmaceutical application for obesity and metabolic syndrome.