1.Over-treatment and under-intervention for acute pancreatitis
Chinese Journal of Hepatobiliary Surgery 2011;17(1):5-9
There was never a time in history that so many disciplines and specialists participate and try to lead the clinical management for acute pancreatitis. Chaos remains at bedside, and episodes of under-intervention and especially over-treatment frequently happened. Physicians are easily confused by questions and controversies in management for acute pancreatitis. We have reviewed the articles in acute pancreatitis and made our recommendations based on the latest evidences.
2.Treatment and prognostic predictor of 28 cases with malignant melanoma of the head and neck
China Oncology 2001;11(2):148-150
Purpose:To determine the treatments and prognostic predictors of malignant melanoma of the head and neck. Methods:Surgical treatment and outcome was analyzed for 28 patients with malignant melanoma of the head and neck at department of the head and neck of our hospital (1984-1994). Results:23 patients underwent local excised as the first treatment, and local recurrence was demonstrated in 8 (34.8%). Margin of resection of primary melanoma was divided into narrow excision (≤2 cm) and wide excision (>2 cm), and 5-year survival was 58% and 40%(P<0.01). According to surgical methods, 5-year survival of WE, WE/END and WE/TLND were 80%, 80% and 39%. Conclusions:An excision with 2 cm margin is safe procedure for primary tumor of malignant melanoma of the head and neck. Neck dissection may not be practiced until neck lymph node is positive. Neck dissections differ from the positions of the primary tumors, and the flaps must be raised preferably superficial to the platysma.
3.Promoting innovative basic research in eye science by utilization of modern biomedical tools, technologies and strategies
Chinese Journal of Experimental Ophthalmology 2012;30(8):673-676
Efforts are being made to build up platforms to support basic research of ophthalmology by organizing capable staff,adequate instruments,technical assistance,and by applying practical evaluation and cultivating healthy cultural environment.While significant progress has been achieved with scientific publications and international academic exchanges,the ophthalmology society still has a long way to go to enhance the basic research in the field of eye science.Utilization of modern biomedical tools,technologies and strategies will undoubtedly further improve the efficacy and production in the area of basic research of ophthalmology in this country.
4.Flat-acupotomy for 32 cases of back muscles fasciitis.
Chinese Acupuncture & Moxibustion 2012;32(12):1127-1128
Acupuncture Therapy
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Adult
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Aged
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Fasciitis
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therapy
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Female
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Humans
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Male
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Middle Aged
5.Current Research Status and Analysis of Electroacupuncture Parameters for Post-operative Pain
Tianyi ZHAO ; Qiang XI ; Yi GUO
Shanghai Journal of Acupuncture and Moxibustion 2015;(5):464-467
Objective To find the optimal stimulation parameters of electroacupuncture for incision pain and visceral dragging pain after surgery.Method Databases including the China National Knowledge Infrastructure (CNKI), WanFang (WF), VIP and PubMed were retrieved by using computer. The eligible literatures related to the clinical and experimental studies on electroacupuncture for post-operative pain were summarized and the frequencies of the involved electroacupuncture parameters were counted.Result For incision pain, electroacupuncture was used after surgery, with continuous wave, usually a low frequency ranged 2~15 Hz and a current of 2~5 mA; for visceral dragging pain, electroacupuncture was used before surgery, with sparse-intense wave, alternate frequencies majorly at 2/100 Hz and a medium or low current intensity within patient’s endurance. Conclusion In clinical application, the elctroacupuncture parameters should be chosen carefully according to the type of post-operative pain.
6.Scientific Research and Clinical Application of Stem Cell:a New Ethical Topic in Life Science Century
Chinese Medical Ethics 2015;(5):659-663
Based on the analysis on the most common type of scientific research and clinical application of stem cells, including embryonic stem cells , hematopoietic stem cells and mesenchymal stem cells as the breakthrough point, discusses common phenomenon and problems of ethics , scientific research and clinical study the moral life science century new topic, hope scientists, physicians, ethicists, caused by the administrative departments for pub-lic health thought , promote stem cells healthy and steady development .
7.Detection of vascular endothelial growth factor in transitional cell bladder carcinoma
Yi LIN ; Jun ZHU ; Wanming QIANG
Chinese Journal of Urology 2001;0(10):-
Objective To study the relationship between vascular endothelial growth factor (VEGF) and occurrence and invasiveness of bladder cancer. Methods The concentration of VEGF in urine was examined by ELISA in 36 cases of transitional cell carcinoma of bladder. Results The concentration of VEGF was low (3.73?2.63 pg/ml) in controls whereas it has been high in bladder carcinoma (210.97?154.68 pg/ml ), P
8.Expression and clinical significance of PTEN, Fas and DCR3 in gastric cancer
Yi ZHAO ; Xin DENG ; Qiang WANG
Cancer Research and Clinic 2009;21(2):91-94
Objective To study the expression of PTEN,Fas and DCR3 in human gastric cancer and evaluate their effects on carcinogenesis,cell proliferation,invasion and metastasis of gastric carcinoma,as well as clinical significance.Methods The expression of PTEN,Fas and DCR3 were detected by immunohistochemical method (streptavidin-peroxidase) in the tissues of 75 primary gastric carcinomas and 15 gastric ulcers.Results The positive expression rate of DCR3 in gastric carcinoma tissues was significantly higher than that in normal tissues,and the expression of PTEN and Fas was obviously lower than that in normal tissues (P<0.01).The expression of DCR3 was negatively correlated with Fas and PTEN respectively (r=-0.720,P<0.001; r=-0.336,P<0.001).There was a positive correlation between PTEN and Fas.The expression of PTEN,Fas and DCR3 was closely correlated with lymph node metastasis,clinical stage,histological differentiation grade and tumor depth of gastric cancer,but not related to sex,age and tumor size (P>0.05).Conclusion PTEN,DCR3 and Fas have mutual restrictive relationships in the process of invasion and metastasis in gastric cancer.Detecting the expression of PTEN,Fas and DCR3 in gastric cancer is helpful to judge the malignant biological behavior of gastric cancer at a different angle,which may be considered as reliability index in clinic diagnosis,judging curative effect and monitoring the prognosis of gastric carcinoma.
10.Updated treatment of erectile dysfunction after prostatectomy.
Qiang DONG ; De-yi LUO ; Hao ZENG
National Journal of Andrology 2015;21(6):483-488
The incidence rate of erectile dysfunction (ED) is reportedly as high as 30-90% after radical prostatectomy for prostate cancer, which seriously affects the patients' quality of life. Penile rehabilitation is defined as the use of any drug or device at or after radical prostatectomy to maximize erectile function recovery. A variety of treatment options are available for post-prostatectomy ED patients, including oral phosphodiesterase 5 inhibitors (PDE5I) , intracorporal injections, vacuum erection device, and penile prosthesis. This article presents an overview of the currently used methods for the drug treatment and penile rehabilitation of the ED patients after radical prostatectomy. It seems proper to recommend daily use of a vacuum erection device plus oral PDE5I in the early postoperative period. For those who fail to respond to this therapy, intraurethral alprostadil, intracorporal injections, or a penile prosthesis could be considered.
Alprostadil
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administration & dosage
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Combined Modality Therapy
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Erectile Dysfunction
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etiology
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therapy
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Humans
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Male
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Penile Erection
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Penile Prosthesis
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Phosphodiesterase 5 Inhibitors
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administration & dosage
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Prostatectomy
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adverse effects
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Quality of Life
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Recovery of Function
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Vacuum