1.Study on controlling the blood glucose level of gestational diabetes mellitus sufferer regularly during labor
Dan SHAN ; Huixia YANG ; Xiaomei HAN ; Yi ZHAO
Chinese Journal of Obstetrics and Gynecology 2000;0(11):-
Objective To study the maternal blood glucose management of gestational diabetes mellitus during the labor and relationship of maternal blood glucose in labor and neonatal blood sugar. Methods A prospective study on maternal blood glucose monitoring and control during labor was carried in 40 pregnant women with abnormal glucose metabolism. We adjusted maternal blood glucose by low-dosage constant insulin drop during labor. Results Maternal blood glucose in labor arranged between 3.8 ~ 11.2 mmol/L,and low-dosage constant insulin drop was used in 17 cases (42.5%). The neonatal blood glucose was (4.0?1.5)mmol/L following delivery and (3.9?1.0)mmol/L at 24-hour postpartum. There were 2 cases with neonatal hypoglycemia. The neonatal blood glucose of the rest 23 cases was (4.2?1.5)mmol/L,and (3.9?1.0)mmol/L at 24-hour postpartum,and 1 case with neonatal hypoglycemia. There was no the difference of the blood glucose level of newborns between mothers with abnormal glucose metabolism and the normal pregnant women. Conclusion It is necessary to monitor and control the blood glucose level by low dose constant insulin during labor in pregnant women with abnormal glucose metabolism.
2.Study of murine hematopoietic stem/progenitor cell mobilized by recombinant human interleukin 11 combination with granulocyte-colony stimulating factor.
Fan-yi MENG ; Zu-jun JIANG ; Zheng-shan YI ; Dan XU
Chinese Journal of Hematology 2003;24(5):225-227
OBJECTIVETo study the recombinant human interleukin 11 (rhIL-11) in combination with granulocyte-colony stimulating factor (rhG-CSF) for mobilizing peripheral blood stem/progenitor cells in C57BL/6 mice.
METHODSrhIL-11,250 micro g x kg(-1) x d(-1) per mouse alone or in combination with rhG-CSF 250 micro g x kg(-1) x d(-1) per mouse was administered to C57BL/6 mice from day 1 to 7. The changes of peripheral white blood cell count (WBC), platelet counts (BPC) and hematopoietic stem/progenitor cells yields were observed.
RESULTSThe results showed that rhIL-11 alone or in combination with rhG-CSF resulted in increase in absolute numbers of WBC, BPC, CD(34)(+) cells, and CFU-GM, CFU-E, CFU-MK yields in peripheral blood more than those of control (P < 0.001). The yields of CFU-MK was significantly more than that of rhG-CSF group (P < 0.001).
CONCLUSIONrhIL-11 alone or in combination with G-CSF could significantly mobilize hematopoietic stem/progenitor cells from bone marrow into peripheral blood.
Animals ; Drug Synergism ; Female ; Granulocyte Colony-Stimulating Factor ; pharmacology ; Hematopoietic Stem Cell Mobilization ; methods ; Hematopoietic Stem Cells ; cytology ; drug effects ; Humans ; Interleukin-11 ; pharmacology ; Male ; Mice ; Mice, Inbred C57BL ; Recombinant Proteins ; pharmacology
3.Osteoid osteoma of the scapula associated with synovitis of the shoulder: a case report.
Jun YI ; Shan-wu WEI ; Nan-nan YI ; Jian YANG ; Dan XU
China Journal of Orthopaedics and Traumatology 2009;22(6):472-473
Adolescent
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Bone Neoplasms
;
complications
;
Humans
;
Male
;
Osteoma, Osteoid
;
complications
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Scapula
;
pathology
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Shoulder Joint
;
pathology
;
Synovitis
;
complications
5.Soft tissue profile changes in micrognathia after distraction osteogenesis.
Xiao-Hui FU ; Jan CHEN ; Fei-Yun PING ; Feng-Guo YAN ; Yi-Dan SHAN
Chinese Journal of Plastic Surgery 2008;24(4):271-274
OBJECTIVETo evaluate the effect of distraction osteogenesis for severe micrognathia by comparing the pre- and post-operative profile and mentolabial relationship.
METHODS16 cases underwent temporal-mandibular joint plasty and temporal fasciomuscular flap transfer. The mandibular distraction began at the 5th postoperative day at a rate of 0.8 mm a day, two times a day. Bony and soft tissue cephalometry were performed before and after operation. T-test was used to study the change after distraction osteogenesis.
RESULTSThere were significant differences in facial convexity, lower facial height, lower lip length, inter-labial distance, the ratio of lip to mental, the distance from lip to esthetic plane, the depth of mentolabial crease and the thickness of mental soft tissue.
CONCLUSIONSMandibular distraction osteogenesis can markedly improve the soft tissue profile of the middle and lower face for severe micrognathia.
Child ; Child, Preschool ; Facial Muscles ; pathology ; Humans ; Male ; Micrognathism ; pathology ; surgery ; Osteogenesis, Distraction ; Postoperative Period
6.Effect of high glucose and high insulin on NE-induced cardiac hypertrophy of the cultured myocardial cells.
Qing-Feng ZHOU ; Hong-Xin WANG ; Yi-Wei WANG ; Li-Juan FU ; Dan SHAN ; He LIU
Chinese Journal of Applied Physiology 2005;21(3):305-309
AIMTo study the effect of diabetes-like environment on the cardiac hypertrophy, cultured cardiomyocytes were used to study the effect of high insulin and high glucose on norepinephrine (NE)-induced cardiac hypertrophy.
METHODSUsing cultured myocardial cells as a model, the cellular hypertrophy was observed. The contracting frequency was counted by the inverted microscope, the protein content was assayed with Lowry's method, the cardiomyocytes' volumes were measured by computer photograph analysis system, the protein synthesis was assayed with [3H] leucine intake method.
RESULTSThe total cellular protein content, cellular volumes, cellular protein synthesis showed an increase in high insulin group and high glucose group compared with control group. High insulin and high glucose and NE group showed a further increase compared with high glucose and NE group.
CONCLUSIONThe high insulin itself induces hypertrophy of the cultured myocardial cells slightly. Meanwhile, imitating diabetes-like environment with high insulin and high glucose and NE can further accelerate hypertrophy of the cultured myocardial cells.
Animals ; Animals, Newborn ; Cardiomegaly ; chemically induced ; metabolism ; Cells, Cultured ; Glucose ; metabolism ; Insulin ; pharmacology ; Myocytes, Cardiac ; drug effects ; metabolism ; Norepinephrine ; adverse effects ; Rats ; Rats, Sprague-Dawley
7.Application of computer aided design-computer aided manufacture technique in mandible defect reconstruction with individual titanium prosthesis.
Xin XU ; Jun-lie YAN ; Fei-yun PING ; Jun CHEN ; Feng-guo YAN ; Yi-dan SHAN
Chinese Journal of Stomatology 2011;46(7):422-424
OBJECTIVETo investigate the application of computer aided design-computer aided manufacture (CAD-CAM) technique in the reconstruction of mandible defect with individual titanium prosthesis.
METHODSSix patients with large mandibular ramus and angle tumor were spiral CT scanned preoperatively, and the CAD-CAM was used to design and make individual titanium prosthesis for reconstructing the mandibular defects after resection of the tumor. The prosthesis were assembled during operation. Postoperative follow-up period was 9 - 38 months.
RESULTSThe design and manufacture of titanium prosthesis by use of CAD-CAM technique was convenient and the prosthesis fitted the defects very well. The outline of the face, the occlusion and function were restored. After 9 - 38 months of follow-up, the mandibular symmetry was good.
CONCLUSIONSThe application of CAD-CAM provided accurate simulation and fast manufacturing process for the titanium prosthesis in the repair of mandibular defect.
Adult ; Ameloblastoma ; rehabilitation ; surgery ; Computer Simulation ; Computer-Aided Design ; Female ; Follow-Up Studies ; Humans ; Male ; Mandible ; surgery ; Mandibular Neoplasms ; rehabilitation ; surgery ; Mandibular Prosthesis Implantation ; Mandibular Reconstruction ; Middle Aged ; Prosthesis Design ; Titanium ; Tomography, Spiral Computed ; Young Adult
8.Diagnosis and treatment of prostatic malignant mesenchymal tumors: Analysis of 20 cases.
Ke-bing YANG ; Xiang-yi ZHENG ; Jin-dan LUO ; Shan-wen CHEN ; Hong-Zhou MENG ; Bai-hua SHEN ; Song-liang CAI ; Li-ping XIE
National Journal of Andrology 2015;21(4):308-314
OBJECTIVETo explore the diagnosis, treatment, and prognosis of prostatic malignant mesenchymal tumors (PMMT).
METHODSWe retrospectively analyzed the clinical and follow-up data about 20 cases of PMMT and reviewed the literature relevant to the diagnosis, treatment, and prognosis of the disease.
RESULTSBased on the results of pathology and immunohistochemistry, the 20 PMMT cases included leiomyosarcoma (n = 7), rhabdomyosarcoma (n = 5), prostatic stromal sarcoma (n = 3), chondrosarcoma (n = 1), and undifferentiated PMMT (n = 4). Twelve of the patients were treated by radical prostatectomy (3 concurrently by sigmoid colostomy and 1 by cystostomy), 2 by pelvic tumor resection following arterial embolization, 1 by total pelvic exenteration, 1 by colostomy with pelvic lymph node biopsy, and 4 by conservative therapy because of metastasis to the lung, pelvis and bone. Of the 20 patients, 9 died of systemic metastasis within 3 months after treatment, 3 died at 6, 7, and 14 months, respectively, 3 survived with tumor for 5, 11, and 12 months, respectively, 2 survived without tumor for 12 and 24 months so far, all subjected to periodic chemotherapy postoperatively, and 3 lost to follow-up.
CONCLUSIONPMMT is a tumor of high malignancy and rapid progression, for which transrectal ultrasound-guided biopsy remains the main diagnostic method. The clinical stage of the tumor is an important factor influencing its prognosis and the survival rate of the patients can be improved by early diagnosis and combined therapy dominated by radical prostatectomy.
Combined Modality Therapy ; methods ; Humans ; Immunohistochemistry ; Male ; Mesenchymoma ; mortality ; pathology ; therapy ; Prognosis ; Prostatectomy ; Prostatic Neoplasms ; mortality ; pathology ; therapy ; Retrospective Studies
9.A complex urinary fistula after Bricker ileal conduit.
Fa-Jun QU ; Jing-Fei TENG ; Xin-Gang CUI ; Yi GAO ; Lei YIN ; Yu-Shan LIU ; Ya-Cheng YAO ; Dan-Feng XU
Chinese Medical Journal 2013;126(7):1246-1246
Aged
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Humans
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Male
;
Urinary Diversion
;
adverse effects
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Urinary Fistula
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diagnosis
;
etiology
10.Study of sleep features in patients with temporal lobe epilepsy
Shan MAO ; Li-Ping PAN ; Yan-Ping REN ; Juan CAO ; Dan WU ; Yi-Jun SONG
Tianjin Medical Journal 2018;46(1):70-73
Objective To study sleep characteristics in patients with temporal lobe epilepsy (TLE) through polysomnography (PSG). Methods Twenty-five TLE patients (TLE group) and eighteen healthy volunteer subjects (control group) were recruited to our study. Patients of two groups were evaluated by whole-night PSG, including total time in bed (TIB), total sleep time (TST), sleep efficiency (SE), sleep latency (SL), rapid eye movement latency (REML), wake after sleep onset (WASO), the percentages of non-REM (NREM) 1, 2 and 3 stages and the percentages of rapid eye movement (REM) occupied TST (N1%, N2%, N3%and REM%), the apnea-hypopnea index (AHI), hypopnea index, mean oxygen saturation (SpO2) and nadir SpO2, periodic leg movements (PLMs) index and PLMs index of REM sleep, sleep stage shifts (SSS) and sleep stage shifts per hour (SSS/h), NREM1, NREM2, NREM3 and REM sleep stage and wake shifts (abbreviated as N1, N2, N3, REM and W) and their proportions of SSS (abbreviated as N1/SSS, N2/SSS, N3/SSS, REM/SSS and W/SSS). Results Compared with control group, WASO, PLMs, PLMs index of REM sleep, SSS, SSS/H and N2 were significantly increased in TLE group. Moreover, compared with control group, SpO2 was decreased in TLE group (P<0.05). Conclusion Our results suggest that TLE patients have sleep disorder manifested as disorder of sleep structure, increased incidents of respiratory and motion events.