1.The ocular fundus manifestations of Lyme disease in Fujian
Ophthalmology in China 1994;0(02):-
This paper reported 15 cases of Lyme diseases including central serous choroiretinopathy 11 cases, optic neuritis 2 cases, Neuroretinitis 1 case, optic atrophy secondary by papilladema 1 case. The authors suggested that serological test of Lyme disease should be taken routinely in ocular disease, especially in epidemic areas. The ophthalmic sign of Lyme disease may be differ in different areas.
2.Nursing of emotional disorder in patients with alcohol dependence
Chinese Journal of Practical Nursing 2011;27(32):10-11
Objective To analyze the nursing effect of emotional disorder in patients with alcohol dependence.Methods From January 2009 to February 2010,81 patients in our hospital with emotional disorder of alcohol dependence were randomly divided into the observation group (41 cases)and the control group (40 cases).The control group was given routine nursing care,and the observation group was given enhanced care for emotional disorders on the basis of routine nursing care,the clinical results of two groups were compared.Results In the observation group,the re-drinking rate and readmission rate were19.5 % and 7.3%,significantly lower than 40.0% and 27.5% of the control group,the time interval of re-drinking of the observation group was significantly longer than the control group,the anxiety and depression scores were significantly better than the control group.Conclusions To give enhanced care on the basis of routine nursing care for patients with emotional disorders because of alcohol dependence has better clinical effect,it contributes to the patients′ rehabilitation.
3.Recent Advance in Bacteriophage Therapy
Microbiology 2008;0(07):-
At the time of phage’s discovery, phage therapy was regarded as a possible treatment method against bacterial infection. Although phage therapy was used to treat and prevent bacterial infection in the former Soviet Union and Eastern Europe, it was abandoned by the West in the 1940s with the arrival of the antibiotic era. However, the ongoing evolution of bacterial multidrug-resistance has recently motivated the Western scientific community to reevaluate phage therapy for bacterial infections that are incurable by conventional chemotherapy. With the indepth study of phages, it’s increasingly acknowledged that phages, as the medicine to cure bacterial infection, are convenient, safe and efficient therapeutics. This paper summarizes the recent years’ advanced researches in this area.
4.Advances in mechanisms for inflammation-associated colon carcinogenesis and chemoprevention
Acta Pharmaceutica Sinica 2022;57(5):1273-1281
Colorectal cancer is a common malignant tumor of digestive tract, and the risk of inflammatory bowel disease developing into colorectal cancer is significantly increased. Immune signaling pathways NF-
5.Assessing stroke patients with the International Classification of Functioning, Disability and Health core sets
Chinese Journal of Physical Medicine and Rehabilitation 2009;31(11):748-752
Objective To investigate the functional states of stroke patients using the International Classification of Functioning, Disability and Health (ICF) core sets for stroke. Methods Fifty in-patients with stroke participated in this study. Twenty-five patients less than one month after a stroke were assigned to the acute group, and another 25 patients with more than one month since their stroke were assigned to the sub-acute and chronic group. All the patients were assessed using the Glasgow coma scale, Rankin grading and the Barthel index. The ICF core set for stroke assessment was also used with both groups. The data was analyzed by using a Chi squared frequency test. Results Rankin grades and Barthel indices were significantly different between the two groups, and the functional states in the acute group were better than those in the sub-acute and chronic group. Some of the items, such as consciousness state, functions of structures adjoining the eyes, hearing, substitutive sound, accessory respiration, temperature regulation and protection function of the skin had no significant difference between the groups. The number of patients suffering from disorders of joint motion, joint stability, muscle endurance and control of voluntary movement was significantly greater in the sub-acute and chronic group than in the acute group. Both groups were influenced to different degrees by most of the environmental factors. Conclusion The ICF core sets correctly indicated joint motion, joint stability, muscle endurance and control of voluntary movement difficulties of stroke patients.
6.Therapeutic Effect of Atomoxtine in Attention Deficit Hyperactivity Disorder with Comorbidity
qian-bo, CHEN ; yi, ZHOU ; tong, XU
Journal of Applied Clinical Pediatrics 2004;0(12):-
Atomoxetine is a noradrenaline transmitter reuptake inhibitor which can selectively inhibit presynaptic noradrenaline transport protein,strengthen noradrenaline's resupination effect,and increases noradrenaline's activity released by synaptic cleft to improve the symptoms of the attention deficit hyperactivity disorder(ADHD)patients.ADHD patients often accompany with other psychological diseases like oppositional defiant disorder,anxiety disorder,which may hinder the diagnosis of ADHD.There is still no accepted effective medicine nowadays.Currently,research on the treatment of the ADHD is more and more popular.Good therapeutic effect of atomoxetine to treat ADHD has been found in resent studies.This article summarized the current management of using atomoxetine to treat ADHD.
7.Study on Correlation between Postmenopausal Osteoporosis and TCM Constitution of Patients
Yi SUN ; Peijian TONG ; Luwei XIAO
Journal of Traditional Chinese Medicine 1992;0(08):-
Objective To study the distribution of TCM constitution of patients with postmenopausal osteoporosis to analyze the correlation between constitution and osteoporosis.Methods The pre-designed questionnaire and the method of case-control were used to classify and analyze the constitution of postmenopausal osteoporosis patients and normal population for comparison to understand the correlation between constitution and osteoporosis.Results The ratio of constitution type in two groups had statistical difference(P
8.The Diagnosis and Differential Diagnosis of Atypical Persistent Hyperplastic Vitreous by Color Doppler Ultrasonics
Xinlin LIN ; Yi TONG ; Shuqiang CHENG
Journal of Chinese Physician 2002;0(S1):-
Objective To explore the color dopplor imaging feature of atypical persistent hyperplastic primary vitreous(PHPV) and its value in differential diagnosis of white pupil. Method Color doppler ultrasonic detection was used to observe various types of white pupil, and the follow up analysis was performed. Results Among 15 eyes of 12 patients,3cases were bilaterally abnormal.Typical PHPV imaging was displayed in 11 eyes and atypical PHPV imaging was showed in 3 eyes.One eyes with retinoblastoma was wrongly diagnosised as PHPV.The arterial flow signal was detected in the central part of hyperplastic vitreous body in 11 eyes. Conclusion The arterial flow signal in hyperplastial vitreous body was a essential evidence in the diagnosis and differential diagnosis of PHPV.
9.Expression characteristic of serum high-sensitivity C-reactive protein in coronary heart disease
Banglu XUE ; Tong LIU ; Yi LIU
International Journal of Laboratory Medicine 2006;0(02):-
Objective To discuss the expression characteristic of high-sensitivity C-reactive protein(hs-CRP) in coronary heart disease.Methods 115 patients of coronary heart disease confirmed by coronary angiography were randomly recruited, including 42 cases of acute myocardial infarction(AMI),34 cases of unstable angina pectoris(UAP) and 39 cases of stable angina pectoris(SAP). Another 50 patients of healthy persons were recruited as control group. Their levels of serum hs-CRP were determined by particle enhanced immuoturbidimetric method at the analysis instrument of Olympus AU2700.Later the variation of hs-CRP before and after treating was analysed.Results hs-CRP concentration of CHD patients was significantly higher than that of the control group(P
10.Effect of total flavones from stem and leaf of Scutellaria baicalensis on the blood pressure of normal and renal arterial stenosis rat models
Wenjie YI ; Limin ZHANG ; Jiming TONG
Chinese Journal of Tissue Engineering Research 2006;10(31):179-181
BACKGROUND: The effective fraction of stem and leaf of Scutellaria baicalensis, total flavones from stem and leaf of Scutellaria baicalensis (SSTF) can improve blood flow of coronary artery and cerebral blood flow,prolong the time of cruor and prothrombin and decrease blood lipid.OBJECTIVE: To observe the effect of SSTF on blood pressure of normal rats and rat models of renal artery stenosis.DESIGN: A completely randomized and controlled experiment.SETTING: Institute of Traditional Chinese Medicine, Chengde Medical College (Key Laboratory of Research and Exploiture of Traditional Chinese Medicine in Hebei Province) MATERIALS: Totally 70 Wistar rats, aged 2 months old , of clean degree, with body mass of (250±50) g, male and female in half, with permission number of 01-3003 , were provided by the Experimental Animal Research Institute, Chinese Academy of Medical Sciences. SSTF was provided by the phytochemical laboratory of Institute of Traditional Chinese Medicine, Chengde Medical College; Niuhuangjiangya pian was produced by Shiyitang Pharmaceutical Factory, Hayao Company (batch number:9802304).METHODS: The experiment was conducted in Institute of Traditional Chinese Medicine, Chengde Medical College from January to October 1999. The rats were raised in the environment of (22±1) ℃, with relative humidity of 50%-55%, of daylight and darkness for 12 hours for each. ①In the experiment 1, we studied the effect of SSTF on the blood pressure of normal rats. Totally 30 Wistar rats were randomly divided into SSTF group of 100 mg/kg (n=10, 100 mg/kg SSTF), SSTF group of 50 mg/kg (n=10, 50 mg/kg SSTF), and normal saline control group (n=10, 0.5 mL /100 g normal saline). Before being administrated, rats were anaesthetized by intraperitoneal injection of pentobarbital sodium. Blood pressure was recorded by MecLab/4e four-channel physiologic instrument. Then intragastric administration of SSTF and normal saline were performed on the rats in SSTF groups and normal saline control group respectively. Thirty minutes later, the changes of blood pressure of rats in each group were observed successively. ②In the experiment 2, we studied the effect of SSTF on the blood pressure of model rats with hypertension induced by renal artery stenosis. The rest 40 Wistar rats were randomly divided into SSTF group of high dosage, SSTF group of low dosage, normal saline control group, Niuhuangjiangya pian group, with 10 rats in each group. Rats in each group were created into rat models with hypertension induced by renal artery stenosis according to methods from the literatures. Two weeks after operation, intragastric administration of 100 mg/kg SSTF, 50 mg/kg SSTF, 0.5 mL/100 g normal saline and 1 200 mg/kg Niuhuangjiangya pian were daily performed on the rats in four groups respectively for one month successively. Carotid blood pressure of rats in all groups was measured.MAIN OUTCOME MEASURES: ① The effect of SSTF on the blood pressure of normal rats. ②The effect of SSTF on the blood pressure of model rats with hypertension induced by arteria renalis stenosis.RESULTS: ① Effect of SSTF on the blood pressure of normal rats: Blood pressure of SSTF group of 50 mg/kg and SSTF group of 100 mg/kg presented a little decrease compared with before administration. There was no significant difference when compared with normal saline control group (P > 0.05). ②Effeet of SSTF on the blood pressure of model rats with hypertension induced by arteria renalis stenosis: Blood pressure of rats with hypertension in normal saline control group was significantly increased after modeling; Blood pressure of rats with hypertension in SSTF group of 50 mg/kg , SSTF group of 100 mg/kg and Niuhuangjiangya pian group was significantly lower than that in the normal saline control group, especially significantly in SSTF group of 100 mg/kg [(126.3±14.5),(120.2±15.9),(127.8 ±23.4 ) ,(139.6±15.8) mm Hg; P < 0.05-0.01].CONCLUSION: SSTF has the significant hypotensive effect on model rats with hypertension; it does not have obvious effect on normal rats.