1.Analyses on Chinese Excellent Traditional Medical Ethics Dealing with theDoctor-patient Relationship
Chinese Medical Ethics 2015;(4):514-516
There are excellent medical ethics dealing with the relationship between doctors and patients in ancient China.This paper elaborated them from respecting for life, loving to save; skill specialization, theory and practice both excellent;gentle demeanor, gentle humility;universal equality;honest and upright, etc.Them provide reference for improving the doctor-patient relationship, medical personnel professional moral esteemremodeling.
2.Radial keratotomy for keratoconus
Ophthalmology in China 1993;0(01):-
15 consecutive eyes of 13 patients with kerato- conus were treated with radial keratotomy and follo- wed up periodically about 1 year.The visual acuity of all eyes was improved significantly,in the early stage after surgey.The 12 eyes were examined one year postoperatively,1 eye maintainning good result,5 eyes obtainning some improvement of vision and flatt- ening of central cornea,6 eyes of which 4 had adv- anced corncal cones gainning no visual benefit from the surgery.Radial keratoto my appears to be effec- tive in early case of keratoconus,however the long- term result is still not known.
3.To Facilitate Personalize Information Service in Pharmacology by Means of the Personalized Service Functions of PubMed/Medline
China Pharmacy 1991;0(02):-
OBJECTIVE:To facilitate personalize information service in pharmacology by means of the personalized service functions of PubMed/Medline.METHODS:We reviewed the development process and the functions of My NCBI in the personalized information service in PubMed/Medline.RESULTS:The personalized information service in pharmacology can be achieved by using the multi-functions of PubMed/Medline which included My NCBI,RSS,E-mail,SMS and PDA downloads.CONCLUSION:My NCBI,RSS,E-mail,SMS and PDA downloads、the multi-functions of PubMed/Medline can be counted on to achieve personalized information service.
4.Ethical Research on Quality Control in Drug Clinical Trials
Chinese Medical Ethics 2016;29(4):652-654
Guided by good clinical practice ( GCP) , M hospital cooperated with the Ethics Committee in quali-ty management of clinical trials and took the specific measures including perfecting the institution and standard op-erating procedures, implementing three level quality control institution, strengthening the training of GCP, and closely cooperating with drug and data management of clinical trials, quality control in the clinical trial, ethical re-view and supervision, quality control in the whole process (seamless connection). Seamless connection from the beginning of project acceptance and quality control in the whole process of clinical trials can effectively solve the ex-isting problems in clinical trials and improve the quality of clinical trials.
5.Advances on study of relation between hepatitis C virus and hepatocellular carcinoma
Academic Journal of Second Military Medical University 1981;0(04):-
It is estimated that there are about 0. 17 billion HCV infection cases worldwide. HCV sub-genotype 1b and 2a have been the most common genotypes found in the mainland China. The positive rate of HCV antigen in hepatocellular carcinoma (HCC)/corresponding non-cancer liver tissues in China is between 36. 2% (25/69)-72. 7% (48/66), which is associated with different detection methods. HCV associated HCC usually occurs along with chronic hepatitis→cirrhosis pathway. There was no doubt a correlation between the expression of HCV antigen and liver cell transformation, and the change of the functions of tumor-associated genes. These results show HCV is an important risk factor for development of HCC.
6.Research about the indexes to assess the biological behavior of the giant cell tumor of bone
Cancer Research and Clinic 2006;0(07):-
Recent studies about the GCT are focusing on searching for new standards and indexes to prognose the biological behavior of the GCT because of the traditional standards and indexes have been realized often not agree with to the clinic. we review the lately research about the biological behavior of the GCT, then analyse and sum up the correlative indexes that could be significant in studying the prognosis of the GCT.
7.MRI Diagnosis of the Pyogenic Infection in Gluteus Muscles
Journal of Practical Radiology 2000;0(12):-
Objective To explore the applied value of MRI in diagnosing pyogenic of infection of gluteus muscles.Methods MRI data in 9 cases with pyogenic infection of gluteus muscles proved by operation or biopsy were retrospectively analysed by comparison with the pathological diagnosis.Results The pyogenic infections localized at unilateral gluteus muscles involving single,two or three gluteus muscles in all cases.On MRI,the infective gluteus muscles were swelling diffusely and the infections developed along the long axis of the muscles and most or all gluteus muscles were involved.4 cases appeared as suppurative myositis and 5 cases developed typical abscess.4 cases were accompanied with subcutaneous edema and the abscess broken into skin in one case.Conclusion The pathological characteristics of the stage and extent of the pyogenic infection in gluteus muscles can be displayed by MR imaging.
8.The influence of 4 ℃ cold saline on ultra structure of myocardium of swine after cardiopulmonary resuscitation
Chinese Journal of Emergency Medicine 2010;19(10):1027-1030
Objective To observe the myocardial injury attributed to cardiopulmonary resuscitation, and to evaluate the impact of 4 ℃ saline perfusion on the ultra structure of myocardium. Method Twelve Pekimg white swine were induced to make models of ventricular fibrillation by direct current shock. Cardiopulmonary resuscitation was initiated 4 minutes after ventricular fibrillation established, and 10 swine survived from resuscitation. These swine were randomly(random number ) divided into hypothermia group ( n = 5) ( 4 ℃ saline infusion to lower the temperature) and control group ( n = 5). Haemodynamics were monitored. And ultra structure of myocardium was observed under electron microscope 24 hours later. The Mann-Whitney test was used to compare the consecutive variables of 2 samples. Results The damage to the ultra structure of myocardium, myofilaments and mitochondria, was found in the control group, while that to a much lesser extent in the hypothermia group was observed. Conclusions After cardiopulmonary resuscitation, 4 ℃ saline infusion has a protective effect on myocardium.
9.Mixed prostatic carcinoma: a report of 5 patients and literature review
Journal of Central South University(Medical Sciences) 2009;34(7):646-650
Objective To improve the awareness of rare mixed prostatic carcinoma. Methods We reviewed the clinical data of 5 patients with prostatic mixed tumor and relevant literature to ex-plore diagnosis and treatment for it. Results Patient 1 with mixed small cell carcinoma and adeno-carcinoma of the prostate who underwent transurethral electrovaporization of the prostate (TUVP) and flumamide therapy died of lung metastasis 7 months later. Patient 2 with mixed small cell carcinoma and adenocarcinoma of the prostate who underwent TUVP and bilateral testicular resection died of lung metastasis 10 months later. Patient 3 with adenosquamous carcinoma of the prostate who underwent TUVP, radiation therapy and flumamide therapy died of multiple organ failure 8 months later because of the lung, liver, and multiple bone metastasis. Patient 4 with prostatic adenosquamous carcinoma who underwent cystoprostatectomy combined with urinary diversion has already survived for 1 year. Patient 5 with prostatic carcinosarcoma who underwent cystoprostatectomy, urinary diversion, pelvic lymphadenectomy, and radiation therapy died of lung metastasis 13 months later. Conclusion Mixed prostatic carcinoma is quite aggressive with bad prognosis. Its diagnosis relies on detailed pathological examination and immunohistochemical techniques. Patients with prostate adenocarcinoma should be followed up timely after endocrine treatment or radiotherapy. Radical surgery is most effective for mixed prostatic carcinoma.
10.ULTRASTRUCTURE OF PERINEURIAL CELLS AND FIBROUS LONG-SPACING BODIES (FLS) IN ENDONEURIUM OF NORMAL HUMAN PERIPHERAL NERVE
Acta Anatomica Sinica 1954;0(02):-
The perineurial cells of the small nerve branch of the normal human abdominal wall are observed with electron microscope. The fibrous long-spacing bodies (FLS) are found within the interstitial substance of the endoneurium. 1. 2-5 layers of the perineurial cells surround the nerve fasciculus. The perineurial cells are squamous in shape and the cytoplasm contains microfilaments and pinocytotic vesicles. Each perineurial cell has an obvious basement membrane on its basal surface but the fibroblasts, whatever situated in the endoneurium or on the outer surface of the perineurium, has no basement membrane. Numerous desmosome and some gap junctions between the close attached perineurial cells are demostrated. The collagen fibrils between perineurial cells can be often shown. FLS bodies and collagen fibrils about 45 nm in diameter in the interstitial substance of endoneurium inside perineurial cells are demonstrated. In the connective tissue surrounding the outside of perineurial cells, the collagen fibrils of 80 nm in diameter can be seen, but no FLS bodies present there. 2. FLS bodies in the endoneurial matrix can be demostrated. Most of them closely associated with the basement membrane of the Schwann cells surrounding the unmyelinated nerves but no FLS bodies are found associate with those of the myelinated nerves. A few FLS bodies do not relate to basement membrane and they are invested only with the collagen fibrils. In the longitudinal sections, most of FLS bodies are in spindle shape of various sizes, their longitudinal axes parallel to that of the adjoining collagen fibrils. Sometimes the FLS bodies continue with the collagen fibrils are found. Occasionally, FLS body like a bridge locate between two Schwann cells and its dark bands continue to the basement membrane of the Schwann cells. Two or three FLS bodies may fuse together but their cross bands do not registered at the same level. In the oblique sections, FLS bodies are nearly rectangular in shape, with the cross bands shown, and their appearance do not show greaty difference from those in longitudinal sections. The periodicity of FLS bodies is about 133nm in length; the dark band in it is about 53 nm, which is made of the dense granular substance; the light band is about 80 nm, which is made of a network with approximated parallel microfilaments. There are no further crossstriated structures within the periods. Some problems, such as the role of the perineurial cells, the relationship of FLS bodies with basement membrane, are briefly discussed.