ObjectiveTo study the preventive effects of using acupoint massage therphy to Ⅰbedsore. Methods Divided 60 patients with Ⅰbedsore into 2 groups randomly. Acupoint massage therapy was used in the one group and the routine nursing method was used in another to prevent the Ⅰbedsore, and then compared the incidence rate of the Ⅰbedsore between the 2 groups. Results The incidence rate ofⅠbedsore in the two groups were 3.3% and 20.0% respectively,P

The normal value of parameters of saccade, smooth pursuit and optokinetic nystagmus has been detected by recording the electro-oculograph in 29 healthy subjects.The results are as follows: 1.The reaction time of saccade is 259.04? 74.19,the mean velocity is 216.83?87.51/s in 15? target amplitude.No statistical significance has been found between sexes, but the reaction time is obviously longer in pre-puberty group.2.For smooth pursuit in 40% target velocity, gain is 0.976?0.08, phase lag is 3.95?7.69s,moothness is 0.925?1.49.No statistical significance has been found between sexes.3.In analysing the sequential process of saccade and smooth pursuit, it can't observed the tendency of decrement in latency.4.The gain of OKN in 14?/s velocity is between 0.689-0.808, the gain decreases following the increase of target velocity.The symmetry of OKN is 3.54?15.04% and there are 81.58% of OKN belonging macula type in healthy people.5.When the target velocity is in close each other,the velocity of fast phase of OKN is in close with the velocity of saccade.

Benign lymphoepithelial lesion(BLEL) is known as Mikulicz disease.The clinical manifestation of BLEL mainly includes diffuse painless enlargement of the eye or the monocular lachrymal gland.The etiology and pathogenesis of the disease proposed mainly concerns the sex hormone hypothesis,transforming growth factor-β involvement hypothesis,basal cell hyperplasia invasion hypothesis,and IgG4-related hypothesis,etc..The typical pathological changes are infiltration of lymphocytes in the gland,atrophy of the gland tissue,formation of myoepithelial islands within the duct hyperplasia in the gland caused by infiltration of the tubular expansion.There is no uniform diagnosis criterion for this disease up to now,but it needs to be differentiated from idiopathic orbital inflammatory pseudotumor and Sj(o)gren syndrome in clinical diagnosis.The application of glucocorticoid is the primary treating regimen for benign lymphoepithelial lesion.Local radiation therapy and/or surgery extraction are available to patients unsensitive to glucocorticoid therapy.

Objective To evaluate the effect of endoscopic ultrasonography(EUS)in diagnosing e- sophageal and gastric varices in portal hypertension(PHT)patients.Methods Fifty-three patients with e- sophageal and gastric varices(EV、GV)of decompensation PHT and 20 patients without PHT as control were undergone EUS and esophagogastroduodenoscopy(EGD)simultaneously.EUS detected mainly the EGV,e- sophagus and stomach collateral veins.Results EUS identified EV endoscopically in 29(54.7%)patients. EUS detected GV in 24(45.3%)patients,compared with detection in 18(34.0%)patients by esopha- gogastroduodenoscopy(EGD)(P＜0.001).EUS detected PEV in 27(51%)patients.Distribution rates of PEV in F1,F2 and F3 are 0%,28.6% and 75% respectively.The comparison between groups shows sig- nificant difference(P＜0.001).Splenic vein can be seen in both control and experimental groups with di- ameter 7.5?1.35mm VS 11.5?3.5mm respectively,the difference between two groups is significant(P＜0.001).Proximal diameters of Azygos vein in two groups is 7.36?1.29mm VS 8.77?2.94mm respective- ly.Significant difference can be found(P＜0.05).Conclusion EUS had significant value in the diagnosis of PHT with EV and GV,and especially in detecting abnormalities of extra-luminal veins.

Diabetes mellitus is a metabolic syndrome characterized by hyperglycemia, and is caused by complex interaction between genetic and environmental factors. Diabetes mellitus can lead to various ocular surface disorders, including dry eye, superficial punctuatekeratitis, corneal epithelial defects, and recurrent corneal erosion et al. This review focuses on the domestic and overseas research progress on dry eye in diabetics.

Chitin is one of the most important component in fungal cell wall.Biosynthesis of chitin is a complex processes and needs several chitin synthase isoenzymes.The knowledge of structure,function and regulation of chitin synthases is mainly derived from the study of Saccharomyces cerevisiae.In contrast with the 3 chitin synthases in S.cerevisiae,7 were found in most filamentous fungi.In this review the classification and function of chitin synthases are summerized,and progress in the studies on chitin synthases of filamentous fungi which are of theoretical or medical or agricultural importance,including Aspergillus nidulans,Aspergillus fumigatus and Ustilago maydis are emphasized.Recent ad-vance of research on chitin synthase as antifungal target is also discussed.

BACKGROUND:Recently, periprosthetic femoral fractures have been a common complication after total hip replacement. Vancouver type B1 periprosthetic femoral fractures commonly received internal fixation due to stable femoral prosthesis and less bone defects.
OBJECTIVE:To evaluate the effect of the application of Synthes cable system in the treatment of Vancouver type B1 periprosthetic femoral fractures after total hip replacement.
METHODS:From May 2009 to October 2012, 18 patients with Vancouver type B1 periprosthetic femoral fractures were treated with Synthes cable system in the Department of Orthopedics, Nantong First People’s Hospital. There were 8 males and 10 females with an average age of (62.67±8.67) years ranging 45 to 80 years. They received a further consultation at 1, 3 and 6 months after treatment. The function of hip joint was evaluated by Harrris evaluation standard:ful marks, 100 points, ≥ 90 points, excellent;80-89 points, better;70-79 points, good;<70 points, poor.
RESULTS AND CONCLUSION:Al 18 patients were fol owed up for 6 to 43 months. Mean healing period was (19.06±4.04) weeks. Harris score was (22.3±3.6) points before treatment in 18 cases. Harris score was higher significantly at 1, 3 and 6 months after treatment compared with that before treatment (P<0.01), and the recovery of hip function was good. Results indicated that Synthes cable system could help to restore the normal anatomic structure of femur in the greatest extent, showing simple operation, little injury, high stability and high safety. It is an ideal method for treating Vancouver type B1 periprosthetic femoral fractures.

The polymorphism of Bf was determinated in 234 healthy human sera in Beijing by agarose gel high-voltage electrophoresis and PAGIEF followed by immunofixation. The distribution of Bf phenotypes was observed: SS 171, FS 49, FF 8, SS07 4, FS07 1 and SS045 1. Their allele frequencies were, Bf~s = 0.8462, Bf~F=0.1410, Bf~(S07)=0.0107, Bf~(S045)=0.0021. The distribution of Bf phenotypes was good agreement with the Hardy-weinberg law.The time limits of Bf phenotypes in 22 bloodstain samples was determinated.

Objective To investigate the expression and the effect of nuclear factor-?B(NF-?B) in neonatal sepsis.Methods We separated 77 newborn infants into 3 groups, which were septic group (26 cases),non-septic group (31 cases) and control group (20 cases). NF-?B existed in PBMC was detected in 3 different periods, including at admission, after the 24th hour and 48th hour of admission, of the septic group and the non-septic group by flow cytometry. At the same time, the sample of the septic group and the non-septic group were drawn for blood cultures at admission before using antibiotics.Results The expression of NF-?B in septic group was more significant than that in the other 2 groups (P

Objective To investigate the prevalence of cardiovascular and cerebrovascular diseases in the army old male hypertensive patients in Beijing. Methods From October 2011 to April 2014, old male patients in the geriatric department of the General Hospital of Chi-nese People's Liberation Army were enrolled and categorized into 3 groups: normotensive, well-controlled hypertensive and poorly-con-trolled hypertensive groups. The prevalence of cardiovascular and cerebrovascular diseases was recorded and binary logistic regression was used to analyze the differences among the groups. Results 719 old male patients were enrolled, 228 in normotensive group, 389 in well-con-trolled hypertensive group and 102 in poorly-controlled hypertensive group. Compared to normotensive group, there was more incidence of angina (OR=2.547, P<0.001), myocardial infarction (OR=2.493, P=0.003), cerebral thrombosis (OR=3.438, P=0.003) and peripheral artery atherosclerotic disease (OR=1.766, P=0.026) in the well-controlled hypertensive group, and it was more of angina (OR=4.123, P<0.001), la-cunar infarction (OR=2.810, P=0.020), cerebral thrombosis (OR=3.484, P=0.001) and peripheral artery atherosclerotic disease (OR=3.773, P<0.001) in the poorly-controlled hypertensive group. There was not significant difference of prevalence of cerebral hemorrhage (0.9%, 1%and 1%, respectively). Conclusion In the army old male hypertensive patients in Beijing, control rate of blood pressure was higher than com-mon population, but the prevalence of ischemic diseases was still higher than in the normotensive patients. Anti-hypertension and control of other risk factors could reduce the mobidity of cerebral haemorrahge.