This study was designed to assess the effectiveness of a modified silk ligature twisted with wire for inducing advanced periodontitis. Periodontitis was induced in five premolars and one molar of 20 healthy dogs over a 60-day period. The dogs were divided into four groups according to the ligature-inducing materials used: soft moistened food only, wire ligature (WL), silk ligature (SL) and twisted ligature with silk and wire (SWL). Periodontal indices were recorded, and dental radiographs were taken before and after 60 days of ligation. The ligatures were checked daily and the day the ligature fell out was noted. The period during which the ligatures were maintained was significantly shorter for the SL group compared to the SWL group (p < 0.05). Results of the clinical examination showed that almost all periodontal status parameters including the plaque index, gingival index, clinical attachment level, and bleeding on probing were significantly exacerbated in the SWL group compared to the other groups (p < 0.05). Radiographic evaluation demonstrated that alveolar bone levels were significantly lower in the SWL group than the other groups on day 60 (p < 0.05). These results suggested that experimental periodontitis induced by SWL could be an effective method for investigating periodontitis in canine models.
Alveolar Bone Loss/veterinary ; Analgesics, Opioid/therapeutic use ; Animals ; Dog Diseases/*pathology ; Dogs ; Ligation/instrumentation/methods/*veterinary ; Materials Testing/veterinary ; Pain/drug therapy/veterinary ; Periodontitis/pathology/*veterinary ; Tramadol/therapeutic use

A 14-year-old Maltese dog presented with progressive exophthalmos and external deviation of the right eye. Ultrasonography revealed the presence of a retrobulbar mass and fine-needle aspiration cytology was performed, which detected a malignant mass. There was no evidence of metastasis on thoracic and abdominal radiography. Computed tomography showed no invasion into the bony orbit and no metastasis to the lung or lymph nodes. Exenteration was performed to remove the mass completely. Malignant peripheral nerve sheath tumor was confirmed by histopathological examination.
Adolescent ; Animals ; Biopsy, Fine-Needle ; Dogs ; Exophthalmos ; Humans ; Lung ; Lymph Nodes ; Neoplasm Metastasis ; Neurilemmoma* ; Orbit* ; Peripheral Nerves ; Radiography, Abdominal ; Recurrence* ; Ultrasonography