1.Research on the management standard of medical safety (adverse) events
Yuan YAO ; Yeqin SUN ; Li MAO ; Yongbin LI ; Wei LI ; Wenxin WANG ; Lihua LIU
Chinese Journal of Hospital Administration 2018;34(12):984-988
The authors developed a standard of medical safety ( adverse) events standardization management, according to the principle of medical safety (adverse) event management, domestic and abroad research results and best practices for medical safety ( adverse) events management, as well as the present specifics and practice of hospital management in China. Such a standards is designed to standardize such key points of medical safety ( adverse) event management in China, namely the definition, classification, risk prevention, reports response and continuous improvement, which serves as an icebreaker for scientific management of medical safety (adverse) events.
2.Progress of Microsatellite (GT/CA)n Repeat Polymorphisms in Non-small Cell Lung Cancer
Wenjun YANG ; Yuting FU ; Yeqin YUAN ; Da LIU ; Binyuan JIANG
Cancer Research on Prevention and Treatment 2024;51(3):195-202
Non-small cell lung cancer (NSCLC) is the most important histological type of lung cancer. This disease affects a large number of patients, and the prognosis of advanced patients is poor. Although great progress has been achieved for existing treatment methods, challenges still exist. Cancer is a genetic disease, and its occurrence is accompanied by substantial genomic-sequence instability. (GT/CA)n repeat sequence is a common microsatellite sequence serving as transcriptional function-related regions, DNA-methylation modification sites, and other functional sites. Its polymorphism is closely related to the expression of EGFR, HO-1, and HIF-1α in NSCLC patients. (GT/CA)n repeat sequence is the breakthrough point to explore the molecular mechanism of NSCLC occurrence and development, develop molecular markers for diagnosis and prognosis and epigenetics research. This paper summarizes the studies on (GT/CA)n repeat polymorphisms in NSCLC with the aim of providing references for relevant NSCLC research.