We compared cycloplegic refraction after convenient, less toxic single-dose atropinization with conventional three-day atropinization in esotropic children. We examined sixty children below eight years of age with esotropia. Their eyes were examined by cycloplegic refraction at 90 and 120 minutes after administering a drop of atropine twice at five minutes interval. After eight applications for three days, we performed cycloplegic refraction of their eyes. In the two groups, spherical equivalent and spherical power were statistically significantly different, and it had no statistical significance between the measurement of single-dose atropinization plus 0.5 diopter and three-day atropinization. The side effects were found lesser in single-dose application than conventional three-day applications. The results showed that single-dose atropinization can be substituted for conventional three-day atropinization in clinical practice.
Atropine ; Child* ; Esotropia ; Humans

Drug-induced toxic epidermal necrolysis (TEN) is a bullous erythematous disease that is characterized by the appearance of scaled lesions and large sheets of pilling on the skin. A caseof TEN occured in a 10 month old female patient. The characteristic skin lesions of TEN developed after oral administration of carbamazepine for a partial seizure. Thig case consists of prodrome of malaise, fever, anorexia, and conjunctivity followed by erythema & flaccid bullae formation. Diagnosis was confirmed by histologic findings. This patient was treated with a massive systemic corticosteroid, antibiotics, fluid and electrolytes, and topical measures. Authors experienced an extremely rare case of TEN dur to carbamazepine, So report it with a brief review of literature.
Administration, Oral ; Anorexia ; Anti-Bacterial Agents ; Carbamazepine ; Diagnosis ; Electrolytes ; Erythema ; Female ; Fever ; Humans ; Infant ; Seizures ; Skin ; Stevens-Johnson Syndrome*

Fifty-nine children (75 eyes) with organic amblyopia were investigated to know the distribution and incidence of the optic nerve or retinal lesion, the type of sensory strabismus, and the effect of occlusion therapy in organicamblyopia. Optic nerve lesion was found more frequently than retinal lesion as causes of organic amblyopia. Among these optic nerve lesions, optic nerve hypoplasia and tilted disc were most frequently found, and in the retinal lesion, ROP (retinopathy of prematurity: macular dragging), foveal dysplasia, and myopic degeneration were frequent.Thirty-nine of 59 children with organic amblyopia (66%)showed strabismus and 74.4% of them had horizontal deviation; 17 eyes had esotropia, and 12 eyes exotropia. No vertical eyeball deviation was found. Myopic anisometropia was accompanied in 19 cases. Better visual outcome was obtained after occlusion therapy in cases with tilted disc and ROP according to the degree of these lesions. However, there was no improvement in other cases. Authors suggest that fundus examination should be included in the routine ophthalmologic examination in chlidren with strabismus.
Amblyopia ; Anisometropia ; Child* ; Esotropia ; Exotropia ; Humans ; Incidence ; Optic Nerve ; Retinaldehyde ; Strabismus*

PURPOSE: To evaluate the efficacy and need for boosting of mumps vaccine, we measured the degree of immunity of previously vaccinated healthy children with the age from 15 months to 15 years. METHODS: We measured mumps specific IgG & IgM antibody titers of 96 children, vaccinated at the age of 15 months, with the age from 15 months to 15 years by ELISA.(Enzyme linked immunosorbent assay) RESULTS: The results are as follows 1) Sixty three cases(65.6%) were positive for mumps IgG antibody and 18 cases (18.7%) were positive for IgM antibody. 2) Mumps IgG antibody decreased between the age of 4 to 6 years and after then increased again. CONCLUSIONS: We suggested that the boosting mumps vaccination will be required between the age of 4 to 6 years.
Child* ; Humans ; Immunoglobulin G* ; Immunoglobulin M* ; Mumps Vaccine ; Mumps* ; Vaccination

The questions concerning storage temperature and storage duration of the fortified ophthalmic antibiotic solutions are raised. The aim of the current study is to evaluate the influence of fortified ophthalmic antibiotic solutions on its biological and physical properties according to the storage temperature and duration as time goes by. We examined the changes of pH, absorbance spectra, and anti-microbial activity of cefradine(63mg/ml)and gentamicin sulfate(13.6mg/ml) over a four-week period. The results were as follows: There was no difference between the potency of fortified GM solutions stored at 4 degrees C and that at 24 degrees C for 4 weeks. The cefradine stored 24 degrees C exhibited significant changes in both its tJotency and stability after ithe seventh day of storage. The cefradine stored at 4 degrees C exhibited changes in Its absorbance spectra day by day and potency after 14th day.
Cephradine ; Gentamicins ; Hydrogen-Ion Concentration ; Ophthalmic Solutions*

Pseudohypoparathyroidism is characterized by target cell resistance to the effects of parathyroid hormone and classified into various types depending on the phenotypic and biochemical findings. Pseudohypoparathyroidism type II differs from type I in that the urinary excretion of cAMP is elevated both in the basal state and after stimulation with PTH. We experienced a case of pseudohypoparathyroidism type II in 12year old man who had generalized seizure. He had hypocalcemia, hyperphosphatemia, elevated serum PTH level and urinary basal cAMP. Also he had a normal phenotypic appearance. Bilateral basal ganglia calcifications was detected by CT scan.
Basal Ganglia ; Hyperphosphatemia ; Hypocalcemia ; Parathyroid Hormone ; Pseudohypoparathyroidism* ; Seizures ; Tomography, X-Ray Computed

Pseudohypoparathyroidism is characterized by target cell resistance to the effects of parathyroid hormone and classified into various types depending on the phenotypic and biochemical findings. Pseudohypoparathyroidism type II differs from type I in that the urinary excretion of cAMP is elevated both in the basal state and after stimulation with PTH. We experienced a case of pseudohypoparathyroidism type II in 12year old man who had generalized seizure. He had hypocalcemia, hyperphosphatemia, elevated serum PTH level and urinary basal cAMP. Also he had a normal phenotypic appearance. Bilateral basal ganglia calcifications was detected by CT scan.
Basal Ganglia ; Hyperphosphatemia ; Hypocalcemia ; Parathyroid Hormone ; Pseudohypoparathyroidism* ; Seizures ; Tomography, X-Ray Computed

A clinical review of 34 cases of aortic dissection which were admitted to Yeungnam University hospital between March 1983 and April 1992. The results are as follows: 1. The peak incidence was in 5th, 6th decade and male to female ratio was 1.83:1. 2. The most common cause of aortic dissection was atherosclerosis and hypertension (79%). 3. The most common presenting symptom was pain (73%). but dyspnea, palpable mass, murmur, shock were also observed. 4. Abnormal electrocardiographic finding was myocardial ischemia in 6 cases, arrhythmia in 5 cases, LVH in 5 cases. 5. The X-ray findings showed abnormal aortic contour in 10 cases but normal X-ray finding was observed in 63% of DeBaKey Type III. 6. The most common diagnostic procedure was echocardiogram and abdominal Ultrasonography. 7. The mortality of all cases was 20%, operation mortality was 18% but no death of medically treatment in medical indication.
Arrhythmias, Cardiac ; Atherosclerosis ; Dyspnea ; Electrocardiography ; Female ; Humans ; Hypertension ; Incidence ; Male ; Mortality ; Myocardial Ischemia ; Shock ; Ultrasonography

A retrospective survey was conducted on all children with eye injuries who were admitted to Chonnam National University Hospital from January 1993 to December 1998 to determine demographic, etiologic, and risk factors and to identify trend and preventable causes. Of the 147 children, 116 children(78.9%)were boys and 31 children(21.1%)were girls. The types of injury were categorized into six groups. Several of the patients sustained more than one type of injury;therefore, the total number of injuries(186)is greater than the total number of patients(147). The non-perforating anterior injury was the most frequent type of injury encountered(83 eyes;44.6%). The majority of these patients was diagnosed as hyphema. Penetrating anterior globe injury occurred in 55 children(29.6%). Stick or branch was the most common cause of all injuries, occurring in 20 children(13.6%). Other causes of pediatric ocular trauma were sports-related, BB pellet, fist, traffic accidents, glasses, toy, boomerang etc.Of the 68 children diagnosed as hyphema, 14 children(20.6%)were resulted from sports-related injuries. Of the 52 children of anterior perforating eye injuries, 9 children(17.3%) were resulted from branches or sticks.Of the 147 children admitted for ocular trauma, 87 children(59.2%)required surgical treatment. Primary repair of corneal perforation was the most common operation(17 children;19.5%). The preventable causes of pediatric ocular injuries are sports, toy such as BB pellet and broken glasses, but the most important factors are the control of dangerous play and the adequate adult supervision.
Accidents, Traffic ; Adult ; Child ; Corneal Perforation ; Eye Injuries ; Eyeglasses ; Female ; Glass ; Humans ; Hyphema ; Jeollanam-do ; Organization and Administration ; Play and Playthings ; Retrospective Studies ; Risk Factors ; Sports

PURPOSE: To evaluate the prevalance of morphological variation of the kidney secondary to junctional parenchyma, as well as to analyze the ultrasonographic features of junctional parenchyma. MATERIALS AND METHODS: Two hundred and eighty two kidneys of 141 patient without clinical or radiologic evidence of renal disease were prospectively analysed using ultrasound. In all patients, ultrasonograms were obtained in sagittal, coronal and transaxial planes. The kidney was considered to have morphological variation if the ulrasonogram demonstrated junctional parenchymal defect or line ; those showing such variation were classified as one of three types :continuous, discontinuous, or junctional parenchymal line or defect without junctional parenchyma. The prevalance and ultrasonographic features of the kidneys were evaluated. RESULTS: Morphological variation was noted in 71 cases(25%). the continuous type accounted for 54% of these, the discontinuous type for 38%, and junctional parenchymal defect or line without junctional parenchyma for 8%. In all cases, junctional parenchyma was located approximately at the junction of the upper and middle third of the kidny, and had the same echogenecity as the renal cortex. CONCLUSION: An understanding of the morphological variation of the kidney resulting from junctional renal parenchyma would be helpful in differentiating pseudo tumor from true renal neoplasm.
Humans ; Kidney Neoplasms ; Kidney* ; Ultrasonography*