1.The Effect of Laughter therapy on Interpersonal Relations of Person's Affected by Hansen's Disease.
Kwan Hee LEE ; Seon Hyung KO ; Yeoun Kyoung HWANG
Korean Leprosy Bulletin 2013;46(1):73-83
This study was attempted to explore the effect of laughter therapy on Hansen people's Interpersonal Relations, certify the effect, and use that as a useful means to improve Hansen people's interpersonal ability. The research method, Hansen people receiving outpatient and admission medical examination and treatment at the research institute of Korea Hansen Welfare Association located in Euiwang-si, Gyeonggi-do, and Hansen People residing at Razaro Village, and divided 60 people approving participation at research into 30 as an experimental group and 30 as a control group, and conducted a questionnaire survey. The sex was distributed to 30 males, and 30 females, and this study conducted a laughter therapy to 30 of the experimental group over 8 times in total by 60 minutes for 2 weeks, and for the collected data, analyzed changes to interpersonal relations revealed before and after conducting the laughter therapy program using IBM/SPSS 20.0 program. The major findings of this study are as follows. Verification of effects of a laughter therapy on Hansen people' interpersonal relations indicated that the interpersonal scores of the experimental group statistically came out high, so the laughter therapy is effective in improving Hansen people' interpersonal relations. {Pre-test (M = 3.21) and post-test (M = 3.79) of the results showed a statistically significant difference (p<.001)}. It clarified that the laughter therapy is effective improving males' and females' interpersonal relations, where it has a higher effect on female Hansen people than male people. {(males : pretest (M = 2.93) and post-test (M = 3.48), females : pre-test (M = 3.45) and post-test (M = 4.07}
Academies and Institutes
;
Female
;
Gyeonggi-do
;
Humans
;
Interpersonal Relations*
;
Korea
;
Laughter Therapy*
;
Laughter*
;
Leprosy*
;
Male
;
Outpatients
;
Surveys and Questionnaires
2.High Incidence of Staphylococcus aureus and Norovirus Gastroenteritis in Infancy: A Single-Center, 1-Year Experience.
Kyoung SUNG ; Ji Yong KIM ; Yeoun Joo LEE ; Eun Ha HWANG ; Jae Hong PARK
Pediatric Gastroenterology, Hepatology & Nutrition 2014;17(3):140-146
PURPOSE: The etiology of acute gastroenteritis (AGE) has changed since the introduction of the rotavirus vaccination. The aim of this study was to clarify which common pathogens, both bacterial and viral, are currently causing AGE in infants. METHODS: Infants with acute diarrhea were enrolled. We tested for 10 bacterial pathogens and five viral pathogens in stool specimens collected from infants with AGE. The clinical symptoms such as vomiting, mucoid or bloody diarrhea, dehydration, irritability, and poor oral intake were recorded, and laboratory data such as white blood cell count and C-reactive protein were collected. The clinical and laboratory data for the cases with bacterial pathogens and the cases with viral pathogens were compared. RESULTS: Of 41 total infants, 21 (51.2%) were positive for at least one pathogen. Seventeen cases (41.5%) were positive for bacterial pathogens and seven cases (17.1%) were positive for viral pathogens. Staphylococcus aureus (13 cases, 31.7%) and Clostridium perfringens (four cases, 9.8%) were common bacterial pathogens. Norovirus (five cases, 12.2%) was the most common viral pathogen. Fever and respiratory symptoms were common in the isolated viral infection group (p=0.023 and 0.044, respectively), whereas other clinical and laboratory data were indistinguishable between the groups. CONCLUSION: In our study, S. aureus (41.5%) and norovirus (12.2%) were the most common bacterial and viral pathogens, respectively, among infants with AGE.
C-Reactive Protein
;
Clostridium perfringens
;
Dehydration
;
Diarrhea
;
Epidemiology
;
Fever
;
Gastroenteritis*
;
Humans
;
Incidence*
;
Infant
;
Korea
;
Leukocyte Count
;
Norovirus*
;
Rotavirus
;
Staphylococcus aureus*
;
Vaccination
;
Vomiting
3.Restoration of Spermatogenesis Using a New Combined Herbal Formula of Epimedium koreanum Nakai and Angelica gigas Nakai in an Luteinizing Hormone-Releasing Hormone Agonist-Induced Rat Model of Male Infertility.
Hyun Jun PARK ; Yean Kyoung KOO ; Min Jung PARK ; Yoon Kyung HWANG ; Sung Yeoun HWANG ; Nam Cheol PARK
The World Journal of Men's Health 2017;35(3):170-177
PURPOSE: We investigated the protective effect of a mixture of 2 herbal extracts, KH-465, which consisted of Epimedium koreanum Nakai and Angelica gigas Nakai, on spermatogenesis in a luteinizing hormone-releasing hormone (LHRH) agonist-induced rat model of male infertility. MATERIALS AND METHODS: Seventy-five 12-week-old male Sprague-Dawley rats were randomly divided into 5 groups, containing 15 rats each: a normal control group that received no treatment and 4 experimental groups (I, II, III, and IV) in which an LHRH agonist was administered for 4 weeks to induce spermatogenic failure. Group I received distilled water, and groups II, III, and IV received 200 mg/kg/day of KH-465, 400 mg/kg/day KH-465, and depo-testosterone for 4 weeks, respectively. Weight changes of the testis and epididymis, sperm count motility, and levels of testosterone (T), free T, follicle-stimulating hormone (FSH), luteinizing hormone (LH), superoxide dismutase (SOD), and 8-hydroxy-2′-deoxyguanosine (8-OHdG) were estimated. RESULTS: Body, testis, and epididymis weight showed no significant differences among the control and experimental groups. Treatment with KH-465 increased the sperm count and motility. Serum hormone levels of T, free T, and FSH were not significantly different in the experimental groups, while the LH level was higher than in the LHRH agonist-induced control group, but not to a significant extent. Levels of SOD were higher and 8-OHdG were lower in the groups that received KH-465 than in the LHRH agonist-induced control group. CONCLUSIONS: Our results suggest that KH-465 increased sperm production via reducing oxidative stress and had a positive effect in a male infertility model.
Angelica*
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Animals
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Epididymis
;
Epimedium*
;
Follicle Stimulating Hormone
;
Gonadotropin-Releasing Hormone*
;
Humans
;
Infertility, Male*
;
Lutein*
;
Luteinizing Hormone
;
Male
;
Male*
;
Models, Animal*
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Oxidative Stress
;
Rats*
;
Rats, Sprague-Dawley
;
Sperm Count
;
Spermatogenesis*
;
Spermatozoa
;
Superoxide Dismutase
;
Testis
;
Testosterone
;
Water
4.Cytokine response in Balb/c mice infected with Francisella tularensis LVS and the Pohang isolate.
Eun Ju KIM ; Sang Hee PARK ; Young Sill CHOI ; Soo Kyoung SHIM ; Mi Yeoun PARK ; Man Suck PARK ; Kyu Jam HWANG
Journal of Veterinary Science 2008;9(3):309-315
We investigated the immune response induced by the Francisella (F.) tularensis live vaccine strain (LVS) and the Pohang isolate. After the Balb/c mice were infected intradermally (i.d) with 2 x 10(4) cfu of F. tularensis LVS and Pohang, respectively, their blood and organs were collected at different times; 0, 3, 6, 24, 72, 96, 120 and 168 h after infection. Using these samples, RT-PCR and ELISA analysis were carried out for the comparative study of the cytokines, including TNF-alpha, INF-gamma, IL-2, IL-4, IL-10 and IL-12. In the Pohang-infected mice at 120 h, the liver showed a 53 times higher level of TNF-alpha and a 42 times higher level of IFN-gamma than the respective levels at the early time points after infection. The levels of TNF-alpha and IFN-gamma induced by LVS were 5 times lower than those induced by the Pohang isolate. Also, the organs from the Pohang-infected mice showed higher levels of TNF-alpha, IFN-gamma, IL-10 and IL-12 than the levels in the LVS-infected mice. The blood from the Pohang-infected mice at 120 h revealed about a 40 times increased level of IFN-gamma, and IL-10 was also increased by 4 times at 96 h compared to an early infection time point, while IL-4 was not induced during the whole infection period. These results suggest that F. tularensis may induce a Th1-mediated immune response to in vivo infection and the Pohang isolate has a higher capacity than the LVS to induce an acute immune response in Blab/c mice.
Animals
;
*Bacterial Vaccines
;
Cytokines/*biosynthesis
;
Francisella tularensis/immunology/isolation & purification/*pathogenicity
;
Humans
;
Interferon-gamma/genetics/metabolism
;
Interleukins/genetics/metabolism
;
Korea
;
Liver/microbiology/pathology
;
Mice
;
Mice, Inbred BALB C
;
Polymerase Chain Reaction
;
Tularemia/*diagnosis/*immunology
;
Tumor Necrosis Factor-alpha/genetics/metabolism
5.Transperineal ultrasonography for evaluation of the perianal fistula and abscess in pediatric Crohn disease: preliminary study.
Jae Yeon HWANG ; Hye Kyung YOON ; Wee Kyoung KIM ; Young Ah CHO ; Jin Seong LEE ; Chong Hyun YOON ; Yeoun Joo LEE ; Kyung Mo KIM
Ultrasonography 2014;33(3):184-190
PURPOSE: To assess the feasibility and effectiveness of transperineal ultrasonography (TPUS) for the evaluation of perianal Crohn disease (PCD) in pediatric patients. METHODS: Between September 2010 and August 2013, 64 TPUS examinations were performed in 43 patients (34 males and 9 females; mean age+/-standard deviation, 13.3+/-2.4 years; age range, 6 to 17 years) to evaluate PCD. The pain severity, location, and activity of perianal fistula, the presence of an abscess, and anal canal hyperemia were retrospectively evaluated. Spearman rank correlation analysis was performed to assess the relationship between the severity of the pain and the fistula activity, the presence of an abscess, and anal canal hyperemia. RESULTS: All examinations were successfully performed. Thirty-nine examinations (60.9%) were performed without any pain experienced by the patient, 19 examinations (29.7%) with mild pain, five examinations (7.8%) with moderate pain, and one examination (1.6%) with severe pain. The pain severity was correlated with the fistula activity (P<0.01). An anterior fistula location was more common than a posterior location. Active fistulas and abscesses were identified during 30 examinations (46.9%) and 12 examinations (18.8%), respectively. Anal canal hyperemia was identified in 31 examinations (48.4%). CONCLUSION: TPUS with a color Doppler study is useful for visualizing a perianal fistula or abscess and for assessing its inflammatory activity in pediatric Crohn patients.
Abscess*
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Anal Canal
;
Crohn Disease*
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Female
;
Fistula*
;
Humans
;
Hyperemia
;
Male
;
Pediatrics
;
Perineum
;
Retrospective Studies
;
Ultrasonography*