1.Anti-Amyloid Imaging Abnormality in the Era of Anti-Amyloid Beta Monoclonal Antibodies:Recent Updates for the Radiologist
So Yeong JEONG ; Chong Hyun SUH ; Jae-Sung LIM ; Yangsean CHOI ; Ho Sung KIM ; Sang Joon KIM ; Jae-Hong LEE
Journal of the Korean Society of Radiology 2025;86(1):17-33
Lecanemab and donanemab have received full U.S. Food and Drug Administration (FDA) approval, and subsequently, lecanemab has been approved by the Korean FDA and it has recently entered commercial use in Korea. This has increased interest in anti-amyloid immunotherapy for Alzheimer’s disease. Anti-amyloid immunotherapy has shown potential to modify the progression of the disease by specifically binding to amyloid β, a key pathological product in Alzheimer’s disease, and eliminating accumulated amyloid plaques in the brain. However, this treatment can be accompanied by a side-effect, amyloid-related imaging abnormalities (ARIA), which requires periodic monitoring by MRI. It is crucial to detect ARIA and accurately assess the severity by radiology. The role of the radiologist is important in this context, requiring proficiency in basic knowledge of ARIA, and in diagnosing/evaluating ARIA. This review aims to comprehensively cover aspects of ARIA, including its definition, pathophysiology, incidence, risk factors, assessment of severity by radiology, differential diagnosis, and management.
3.Parathyroid Identification With Near-Infrared Autofluorescence in Thyroid Surgery
Yeong Joon KIM ; Hyoung Shin LEE ; Kang Dae LEE
Korean Journal of Otolaryngology - Head and Neck Surgery 2025;68(3):133-137
Hypoparathyroidism is one of the major complications of total thyroidectomy. This complication can occur when the parathyroid tissue is unintentionally removed or the parathyroid vessels is ligated. Early mapping and localization of the parathyroid tissue would be helpful to prevent such unintended complication. The authors introduce the procedures of parathyroid identification with Near-infrared autofluorescence performed in our institution.
4.Early Administration of Nelonemdaz May Improve the Stroke Outcomes in Patients With Acute Stroke
Jin Soo LEE ; Ji Sung LEE ; Seong Hwan AHN ; Hyun Goo KANG ; Tae-Jin SONG ; Dong-Ick SHIN ; Hee-Joon BAE ; Chang Hun KIM ; Sung Hyuk HEO ; Jae-Kwan CHA ; Yeong Bae LEE ; Eung Gyu KIM ; Man Seok PARK ; Hee-Kwon PARK ; Jinkwon KIM ; Sungwook YU ; Heejung MO ; Sung Il SOHN ; Jee Hyun KWON ; Jae Guk KIM ; Young Seo KIM ; Jay Chol CHOI ; Yang-Ha HWANG ; Keun Hwa JUNG ; Soo-Kyoung KIM ; Woo Keun SEO ; Jung Hwa SEO ; Joonsang YOO ; Jun Young CHANG ; Mooseok PARK ; Kyu Sun YUM ; Chun San AN ; Byoung Joo GWAG ; Dennis W. CHOI ; Ji Man HONG ; Sun U. KWON ;
Journal of Stroke 2025;27(2):279-283
5.Anti-Amyloid Imaging Abnormality in the Era of Anti-Amyloid Beta Monoclonal Antibodies:Recent Updates for the Radiologist
So Yeong JEONG ; Chong Hyun SUH ; Jae-Sung LIM ; Yangsean CHOI ; Ho Sung KIM ; Sang Joon KIM ; Jae-Hong LEE
Journal of the Korean Society of Radiology 2025;86(1):17-33
Lecanemab and donanemab have received full U.S. Food and Drug Administration (FDA) approval, and subsequently, lecanemab has been approved by the Korean FDA and it has recently entered commercial use in Korea. This has increased interest in anti-amyloid immunotherapy for Alzheimer’s disease. Anti-amyloid immunotherapy has shown potential to modify the progression of the disease by specifically binding to amyloid β, a key pathological product in Alzheimer’s disease, and eliminating accumulated amyloid plaques in the brain. However, this treatment can be accompanied by a side-effect, amyloid-related imaging abnormalities (ARIA), which requires periodic monitoring by MRI. It is crucial to detect ARIA and accurately assess the severity by radiology. The role of the radiologist is important in this context, requiring proficiency in basic knowledge of ARIA, and in diagnosing/evaluating ARIA. This review aims to comprehensively cover aspects of ARIA, including its definition, pathophysiology, incidence, risk factors, assessment of severity by radiology, differential diagnosis, and management.
7.Anti-Amyloid Imaging Abnormality in the Era of Anti-Amyloid Beta Monoclonal Antibodies:Recent Updates for the Radiologist
So Yeong JEONG ; Chong Hyun SUH ; Jae-Sung LIM ; Yangsean CHOI ; Ho Sung KIM ; Sang Joon KIM ; Jae-Hong LEE
Journal of the Korean Society of Radiology 2025;86(1):17-33
Lecanemab and donanemab have received full U.S. Food and Drug Administration (FDA) approval, and subsequently, lecanemab has been approved by the Korean FDA and it has recently entered commercial use in Korea. This has increased interest in anti-amyloid immunotherapy for Alzheimer’s disease. Anti-amyloid immunotherapy has shown potential to modify the progression of the disease by specifically binding to amyloid β, a key pathological product in Alzheimer’s disease, and eliminating accumulated amyloid plaques in the brain. However, this treatment can be accompanied by a side-effect, amyloid-related imaging abnormalities (ARIA), which requires periodic monitoring by MRI. It is crucial to detect ARIA and accurately assess the severity by radiology. The role of the radiologist is important in this context, requiring proficiency in basic knowledge of ARIA, and in diagnosing/evaluating ARIA. This review aims to comprehensively cover aspects of ARIA, including its definition, pathophysiology, incidence, risk factors, assessment of severity by radiology, differential diagnosis, and management.
9.Parathyroid Identification With Near-Infrared Autofluorescence in Thyroid Surgery
Yeong Joon KIM ; Hyoung Shin LEE ; Kang Dae LEE
Korean Journal of Otolaryngology - Head and Neck Surgery 2025;68(3):133-137
Hypoparathyroidism is one of the major complications of total thyroidectomy. This complication can occur when the parathyroid tissue is unintentionally removed or the parathyroid vessels is ligated. Early mapping and localization of the parathyroid tissue would be helpful to prevent such unintended complication. The authors introduce the procedures of parathyroid identification with Near-infrared autofluorescence performed in our institution.
10.Parathyroid Identification With Near-Infrared Autofluorescence in Thyroid Surgery
Yeong Joon KIM ; Hyoung Shin LEE ; Kang Dae LEE
Korean Journal of Otolaryngology - Head and Neck Surgery 2025;68(3):133-137
Hypoparathyroidism is one of the major complications of total thyroidectomy. This complication can occur when the parathyroid tissue is unintentionally removed or the parathyroid vessels is ligated. Early mapping and localization of the parathyroid tissue would be helpful to prevent such unintended complication. The authors introduce the procedures of parathyroid identification with Near-infrared autofluorescence performed in our institution.

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