1.Application of Immunohistochemical Stain for Granulocytic Sarcoma.
Yeong Ju WOO ; Chan Hwan KIM ; Jong Eun JOO
Korean Journal of Pathology 1994;28(1):30-37
Granulocytic sarcoma is a rare localized tumor composed of granulocytic precusor cells. Granu-locytic sarcoma occurs in a variety of clinical conditions and it is often misdiagnosed histologically. Differential diagnosis frorh lymphoma or nonhematopoietic malignancies such as undifferentiated carcinoma or sarcoma is difficult in the routing histologic examination. An evaluation of clinical and histopathologic features was done on 4 cases of granulocytic sarcoma which were diagnosed at Pusan Paik Hospital from 1988 to 1992. During the period, 282 cases of myelogenous leukemia were diagnosed. Immunohistochemical reaction for lysozyme, myelopero-xidase, leukocyte common antigen, epthelial membrane antigen and cytokeratin was assessed comparing to lymphoma and undifferentiated carcinoma. The histologic features of the granulocytic sarcoma revealed thin nuclear membrane, fine chromatin pattern and one or two small nucleoli. It also often involved the vascular wall and infiltrated the native structures without destruction. Immunohistochemical stain revealed that all(4 cases) of granulocytic sarcoma showed diffuse and strong positivity for myeloperoxidase, and partial but strong positivity for lysozyme. One case of granulocytic sarcoma was negative and 3 cases revealed focal positive reaction for LCA, and all 4 cases was negative for cytokeratin and EMA. In summary, careful observation under light microscopy with immunohistochemical stain for myeloperoxidase, lysozyme, and LCA is helpful in the differential diagnosis of granulocytic sarcoma from malignant lymphoma and cytokeratin and EMA is useful for differential diagnosis from undifferentiated carcinoma.
Diagnosis, Differential
2.Antimicrobial Effects of Nano-Silver Gauze against Common Bacterial Isolates.
Sun Min LEE ; Eun Kyoung YANG ; Eun Yup LEE ; Yeong Dae KIM ; Chulun L CHANG
Korean Journal of Nosocomial Infection Control 2006;11(2):87-91
BACKGROUND: Silver has been used for disinfection and sterilization. We aimed to confirm the in-vitro antibacterial effects of nanocrystalline silver-coated gauze. METHODS: Fourteen clinical isolates each of Escherichia coli and Acinetobacter baumannii were used. Bacterial suspensions made in tryptic soy broth were exposed to Ordinary and silver-coated gauze. Bacteria were then harvested from the gauze immediately and after 24 h incubation, cultured on blood agar plates and eunmerated for viable counts. The number of colonies was converted into common logarithms for comparison. RESULTS: The number of colonies recovered from silver-coated gauze was significantly lower than those recovered from ordinary gauze when harvested immediately after exposure (E. coli, 3.06 vs 1.73; A. baumannii, 3.13 vs 1.98; P<0.001). After 24 h incubation of exposed gauze, silver-coated gauze produced less than 1 CFU/mL, whereas ordinary gauze produced a number of colonies significantly higher than it did immediately after exposure (E. coli, 4.13; A. baumannii, 4.46; P<0.001). Conclusion: Compared with ordinary gauze, silver-coated gauze was shown to have 99.99% antibacterial effect.
Acinetobacter baumannii
;
Agar
;
Bacteria
;
Disinfection
;
Escherichia coli
;
Silver
;
Sterilization
;
Suspensions
3.The major aortopulmonary collateral arteries in pulmonary atresia with ventricular septal defect: chest radiologic findings.
Sung Jin KIM ; Yeon Hyeon CHOE ; Ji Eun KIM ; Kil Sun PARK ; Dae Yeong KIM
Journal of the Korean Radiological Society 1992;28(6):875-880
The chest radiographs and angiograms were retrospectively evaluated in 47 patients with pulmonary atresia (PA) and ventricular septal defect (VSD) to determine the characteristic findings of major aortopulmonary collateral arteries (MAPCSs) on the chest radiographs. Of 47 patients, 23 had MAPCAs and 24 had only PDA for blood supply of whole right and left lung. Chest radiographs enabled identification of 16 of 23 patients with MAPCAs. The most common finding of MAPCAs was inappropriately large peripheral pulmonary vasculature (n=16, 69.6%). The other findings were tortuosity of pulmonary vasculature (n=12, 52.2%), focal unevendistribution of pulmonary vasculature (n=12, 52.2%), and two descending pulmonary arteries (n=4, 17.4%). When chest radiographs showed two or more findings of MAPCAs, MAPCAs could be differentiated from PDA with statistical significance (p<0.005). It is concluded that chest radiographs may help to identify MAPCAs before angiography if two-dimensional echo ardiography suggests PA with VSD.
Angiography
;
Arteries*
;
Heart Septal Defects, Ventricular*
;
Humans
;
Lung
;
Pulmonary Artery
;
Pulmonary Atresia*
;
Radiography, Thoracic
;
Retrospective Studies
;
Thorax*
4.Phenomenological Research on the Experience of Weight Control Among Nursing Students.
Journal of Korean Academy of Adult Nursing 2009;21(6):718-732
PURPOSE: This study was conducted to discover the essence and the structure of the experiences of weight control by nursing students. METHODS: Participants were 12 nursing students who had tried losing weight at C university in Busan, Korea. The data were collected from June 17 to August 6, 2006. For the purpose of this study, focus group discussions and in depth interviews were employed. RESULTS: The collected data were analyzed by using Giorgi's method. As the results of the analysis, the following four components of experience were derived: My appearance looked abnorml; Measures for self-realization; Pursuit of my own way only; Feelings of accomplishment and self confidence. CONCLUSION: It is necessary to develop an effective weight control program with minimized side effects that are harmful to health, based on the components of the nursing students' experiences in weight control that were identified in this study.
Body Weight
;
Focus Groups
;
Humans
;
Korea
;
Qualitative Research
;
Students, Nursing
;
Weight Loss
5.Factors related to the Health related Quality of Life among Institutionalized Elders.
Journal of Korean Academy of Adult Nursing 2010;22(3):281-290
PURPOSE: This purpose of this study was to identify the factors related to the health related quality of life among institutionalized elders. METHODS: The subjects were 247 elders institutionalized among one of the four nursing homes in Busan. Data were collected through interview with four standardized questionnaires from August to October, 2008. Questionnaires were related to health related quality of life (SmithKline Beecham's Quality of Life scale, SBQoL), quality of sleep(Pittsburgh Sleep Quality index, PSQI), activity of daily living (Katz ADL Index), and depression (Geriatric Depression Scale Short Form Korea, GDSSF-K). Data were analyzed for descriptive analysis, t-test, one-way ANOVA, Pearson's correlation coefficient, and stepwise multiple regression by using SPSS/WIN 17.0 program. RESULTS: The mean HRQoL in the subjects was 6.62 +/- 0.91. Percentage of the respondents reporting sleep disorders were 72.5% and 27.1% reported being vulnerable to depression. The significant predictors of the HRQoL were sleep quality, activity of daily living (ADL), level of education, and depression. The factors accounted for 28.8% of variance in the health related quality of life of institutionalized elders. CONCLUSION: Sleep quality, activity of daily living, and depression need to be considered as the important control factors for improving the health related quality of life in the institutionalized elders.
Activities of Daily Living
;
Depression
;
Korea
;
Nursing Homes
;
Quality of Life
;
Sleep Wake Disorders
;
Surveys and Questionnaires
6.A study on T cell subsets and natural killer(NK) cells of peripheral blood in patients with various cancer.
Jin Yeong HAN ; Soon Ho KIM ; Han Chul SON ; Eun Yup LEE ; Jung Man KIM
Korean Journal of Clinical Pathology 1991;11(1):183-195
No abstract available.
Humans
;
T-Lymphocyte Subsets*
7.A morphometric study of the Korean vertebrae.
Jae Do KANG ; Kwang Yul KIM ; Keun Soo LEE ; Eun Yeong CHOI ; Bong Sun KIM
The Journal of the Korean Orthopaedic Association 1992;27(1):351-359
No abstract available.
Spine*
8.Prolonged Low-dose Chlorpromazine Therapy Induced Skin Pigmentation and Corneal and Lens Opacities.
Bokwon PARK ; Jun Yeong PARK ; YEJI JANG ; Eun Byul CHO ; Eun Joo PARK ; Kwang Ho KIM ; Kwang Joong KIM
Korean Journal of Dermatology 2018;56(9):575-577
No abstract available.
Cataract*
;
Chlorpromazine*
;
Skin Pigmentation*
;
Skin*
9.The Effect of Antihypertensive Therapy on Left Ventricular Mass in Hypertensive Patients.
Kwang Ho KIM ; Sang Man CHUNG ; Hyang In KIM ; Yong Jin JOO ; Yeong Soo LEE ; Ki Yeong KIM ; Eun Soo MOON ; Si Jun CHUNG
Korean Circulation Journal 1992;22(5):831-837
BACKGROUND: Hypertension is the major risk factor for cardiovascular disease. The increased left ventricular mass has been recognized as an independent predictor of morbidity and mortality in hypertensive patients. The assessment of the regression of left ventricular(LV) mass after antihypertensive therapy offers prognostic information. 2D echocardiography has proved a sensitive tool for the detection of the change of LV mass. METHOD: LV mass and LV mass index were measured by area-length method of 2D echocardiography in 26 hypertensive patients and 10 normal control to evaluate the effect of betablocker(group I, n=16) and angiotensin converting enzyme(ACE) inhibitor(group II, n=10) on the regression of LV mass. RESULT: There was a significant increase of LV mass and LV mass index in the hypertensive patients(199.0+/-37.7gm, 119.2+/-21.2gm/m2) compaired to the control(129.7+/-11.7gm, 87.4+/-8.8gm/m2)(p<0.01, p<0.01). After 13.1 week treatment, LV mass was significantly decreased in group I(200.9+/-35.3gm vs 164.7+/-25.4gm)(p<0.01) and group II(195.9+/-43.3gm vs 152.4+/-27.1gm)(p<0.01). The LV mass index was also significantly decreased in group I(120.3+/-20.7gm/m2 vs 98.8+/-15.5gm/m2)(p<0.01) and group II(117.5+/-22.9gm/m2 vs 91.5+/-13.6gm/m2)(p<0.01). CONCLUSION: This results showed that LV mass can be reduced in hypertensive patients who receive beta blocker and ACE inhibitor. The effect of antihypertensive therapy on LV mass should be considered in treatment of the hypertensive patients who had hypertrophied LV.
Angiotensins
;
Cardiovascular Diseases
;
Echocardiography
;
Humans
;
Hypertension
;
Mortality
;
Risk Factors
10.A Case of Late Onset Neonatal Bacteremia and Meningitis Caused by Streptococcus lutetiensis.
Ji Sook KIM ; Yoo Ra HONG ; Hee Yeong YANG ; Chi Eun OH
Korean Journal of Pediatric Infectious Diseases 2014;21(3):219-224
Invasive infection of the Streptococcus bovis group in a neonate is rare. In cases reported to date, the pathogen of neonatal S. bovis infections is usually Streptococcus gallolyticus subsp. pasteurianus (S. bovis biotype II/2). Streptococcus lutetiensis (S. bovis biotype II/1) was identified using 16S rRNA and tuf gene sequence analysis of the isolates from blood and cerebrospinal fluid (CSF) of a fever-presenting 28-day-old male. Blood culture analysis was performed using automatic equipment (VITEK 2) and identified Streptococcus infantarius supsp. infantarius, yet we were unable to get accurate results from the CSF culture. The fever subsided on the second day of hospitalization, and the patient was discharged without neurologic complication after 14 days of antibiotic therapy. In this case, we were able to accurately identify the pathogen using molecular genetic methods. To our knowledge, this is the first case of late onset neonatal bacteremia and meningitis caused by S. lutetiensis.
Bacteremia*
;
Cerebrospinal Fluid
;
Fever
;
Hospitalization
;
Humans
;
Infant, Newborn
;
Male
;
Meningitis*
;
Molecular Biology
;
Sequence Analysis
;
Streptococcus bovis
;
Streptococcus*