Granulocytic sarcoma is a rare localized tumor composed of granulocytic precusor cells. Granu-locytic sarcoma occurs in a variety of clinical conditions and it is often misdiagnosed histologically. Differential diagnosis frorh lymphoma or nonhematopoietic malignancies such as undifferentiated carcinoma or sarcoma is difficult in the routing histologic examination. An evaluation of clinical and histopathologic features was done on 4 cases of granulocytic sarcoma which were diagnosed at Pusan Paik Hospital from 1988 to 1992. During the period, 282 cases of myelogenous leukemia were diagnosed. Immunohistochemical reaction for lysozyme, myelopero-xidase, leukocyte common antigen, epthelial membrane antigen and cytokeratin was assessed comparing to lymphoma and undifferentiated carcinoma. The histologic features of the granulocytic sarcoma revealed thin nuclear membrane, fine chromatin pattern and one or two small nucleoli. It also often involved the vascular wall and infiltrated the native structures without destruction. Immunohistochemical stain revealed that all(4 cases) of granulocytic sarcoma showed diffuse and strong positivity for myeloperoxidase, and partial but strong positivity for lysozyme. One case of granulocytic sarcoma was negative and 3 cases revealed focal positive reaction for LCA, and all 4 cases was negative for cytokeratin and EMA. In summary, careful observation under light microscopy with immunohistochemical stain for myeloperoxidase, lysozyme, and LCA is helpful in the differential diagnosis of granulocytic sarcoma from malignant lymphoma and cytokeratin and EMA is useful for differential diagnosis from undifferentiated carcinoma.
Diagnosis, Differential

Purpose: This study aimed to understand and explore the work experiences of Generation Y nurses in hospital organizations. Methods: Participants were nine nurses with generation Y working in the hospital. Data were collected through individual interviews from December 2, 2022 to June 30, 2023. The transcripts were coded and analyzed using Colaizzi's phenomenological method. Results: A total of 33 formulated meanings were derived from the meaningful 50 statements of nine study participants, and then categorized them into 12 themes with a collection of five theme clusters. Conclusion This study found that Generation Y nurses experienced role confusion and physical and mental burden as they caught in the middle in other generations. Even they were wondering whether to continue working as a nurse, which seems that it is crucial to establish a recognition and compensation system to maintain Generation Y nurses in the field. In addition, Generation Y nurses have been found to endure difficult hospital work and demonstrate patience even when working alone, while also deriving strength from their colleagues. Therefore, it is necessary to establish a program for intergenerational harmony among nurses.

Purpose: This study aimed to understand and explore the work experiences of Generation Y nurses in hospital organizations. Methods: Participants were nine nurses with generation Y working in the hospital. Data were collected through individual interviews from December 2, 2022 to June 30, 2023. The transcripts were coded and analyzed using Colaizzi's phenomenological method. Results: A total of 33 formulated meanings were derived from the meaningful 50 statements of nine study participants, and then categorized them into 12 themes with a collection of five theme clusters. Conclusion This study found that Generation Y nurses experienced role confusion and physical and mental burden as they caught in the middle in other generations. Even they were wondering whether to continue working as a nurse, which seems that it is crucial to establish a recognition and compensation system to maintain Generation Y nurses in the field. In addition, Generation Y nurses have been found to endure difficult hospital work and demonstrate patience even when working alone, while also deriving strength from their colleagues. Therefore, it is necessary to establish a program for intergenerational harmony among nurses.

Purpose: This study aimed to understand and explore the work experiences of Generation Y nurses in hospital organizations. Methods: Participants were nine nurses with generation Y working in the hospital. Data were collected through individual interviews from December 2, 2022 to June 30, 2023. The transcripts were coded and analyzed using Colaizzi's phenomenological method. Results: A total of 33 formulated meanings were derived from the meaningful 50 statements of nine study participants, and then categorized them into 12 themes with a collection of five theme clusters. Conclusion This study found that Generation Y nurses experienced role confusion and physical and mental burden as they caught in the middle in other generations. Even they were wondering whether to continue working as a nurse, which seems that it is crucial to establish a recognition and compensation system to maintain Generation Y nurses in the field. In addition, Generation Y nurses have been found to endure difficult hospital work and demonstrate patience even when working alone, while also deriving strength from their colleagues. Therefore, it is necessary to establish a program for intergenerational harmony among nurses.

Purpose: This study aimed to understand and explore the work experiences of Generation Y nurses in hospital organizations. Methods: Participants were nine nurses with generation Y working in the hospital. Data were collected through individual interviews from December 2, 2022 to June 30, 2023. The transcripts were coded and analyzed using Colaizzi's phenomenological method. Results: A total of 33 formulated meanings were derived from the meaningful 50 statements of nine study participants, and then categorized them into 12 themes with a collection of five theme clusters. Conclusion This study found that Generation Y nurses experienced role confusion and physical and mental burden as they caught in the middle in other generations. Even they were wondering whether to continue working as a nurse, which seems that it is crucial to establish a recognition and compensation system to maintain Generation Y nurses in the field. In addition, Generation Y nurses have been found to endure difficult hospital work and demonstrate patience even when working alone, while also deriving strength from their colleagues. Therefore, it is necessary to establish a program for intergenerational harmony among nurses.

No abstract available.
Interleukin-6* ; Rabbits*

Heterotopic pregnancy occurs when an intrauterine pregnancy co-exists with an ectopic pregnancy. It is a potentially fatal condition, rarely occuring in natural conception cycle. But its incidence is increased since the rise in PID, pelvic surgery, IUD, and advent of assisted reproductive technology involving use of superovulatory drugs and/or in vitro-fertilization. We present a case of intrauterine twin pregnancy and right tubal pregnancy following treatment with in vitro-fertilization. The right tubal pregnancy was diagnosed after rupturing at 6th gestational weeks, and resected via laparoscopy. And healthy twin babies were delivered without complication at 38th gestational week. So we report this case with a brief review of the literatures.
Female ; Fertilization ; Humans ; Incidence ; Laparoscopy ; Pregnancy ; Pregnancy, Ectopic ; Pregnancy, Heterotopic* ; Pregnancy, Tubal ; Pregnancy, Twin ; Reproductive Techniques, Assisted

Background: In this study, we aimed to investigate the recent trends for health care indicators including maternal mortality ratio, infant mortality rate, under-five mortality rate, life expectancy, years of life lost, and healthcare resources in South Korea, North Korea, Germany, Russian Federation, Mongolia, Vietnam, China, Czech Republic, Poland, and Hungary. Methods: We used data from five sources: World Health Organization, Federal Institute for Population Research, World Bank, Organization for Economic Cooperation and Development health statistics, and national statistics. Results: In the early 1990s, health indicators continued to improve in countries that switched to the health insurance system, but the gap widened in North Korea as health indicators worsened. Conclusion The establishment of a sustainable health care system after unification of the Korean peninsula requires substantial changes in the health care system and efforts to improve the health of North Koreans.

PURPOSE: It is well known that use of intranenous methylprednisolone(IVMP)for the patients with idiopathic thrombocytopenic purpura(ITP) is not only as effective as use of intravenous gammaglobulin to mincrease platelets quickly, but also the former is less expensive than the latter. As the adequate dosage of IVMP has not been fully elucidated, we have tried to determine it. METHODS: The subjects were 35 childhood patients below 15 years of age, who were diagnosed with ITP for the first time and whose platelet count was less than 20,000/mm(3) at diagnosis. We divided them into three groups : Group A included 8 cases with IVMP dosage of 5mg/kg/day, Group B included 9 patients with IVMP dosage of 10mg/kg/day, and group C included 18 patients with IVMP dosage of 20mg/kg/day. We checked the platelet count every day after IVMP administration daily for 5 days and also observed for side effects if any. RESULTS: After IVMP administration, we obseved increasing tendency of platelets in all three groups, of which group C was more rapid and higher in increasing platelets than the other groups(p<0.05). After IVMP therapy for 5 days, cases with platelets>20,000/mm(3) were 6(75%) in group A, 7(78%) in group B, and 18(100%) in group C. Cases with platelets >50,000/mm(3) were 5(63%), 6(67%), 17(94%) in groups A, B, C, respectively, and cases with platelets> 100,000/mm(3) were 3(38%), 5(56%), 14(78%), in group A, B, C, respectively. And there were no remarkable side effects except a case of transient hypertensive headache in group C. CONCLUSIONS: We concluded that the effectiveness of IVMP therapy for increasing platelets was more rapid and higher in group C than in group A or B, and side effect was minimal.
Child* ; Diagnosis ; Headache ; Humans ; Methylprednisolone* ; Platelet Count ; Purpura, Thrombocytopenic, Idiopathic*

PURPOSE: The purpose of this study was to examine the effects of aroma-inhalation on depression, sleep, mood, and smell in stroke patients and their caregivers. METHOD: This study employed one group pretest-posttest repeated design. Data were collected at three time points: baseline(pre-test), 10 days and 20 days after the intervention(post-test1 and post-test2, respectively). The sample included a total of 23 subjects. Data were analyzed by SPSS 12.0 program using repeated measure ANOVA. RESULTS: Depression was not statistically significant difference among pre-test, post-test1 and post-test2. Sleep was improved after intervention: 37.61+/-7.41(pre-test), 41.22+/-8.26 (post-test1), 44.33+/-7.67(post-test2)(F=8.182, p=.001). Mood was significantly improved after intervention: 16.95+/-4.89(pre-test), 14.89+/-6.31 (post-test1), 12.11+/-5.04(post-test2). Smell including smell perception, discomfort due to smell and relation between age and smell was significantly improved after intervention: 2.63+/-1.20(pre-test). 2.00+/-1.16(post-test1), 1.63+/-.96(post-test2)(F=6.176, p=.006) in smell perception, 2.50+/-1.10 (pre-test). 1.81+/-.91(post-test1), 1.19+/-.40(post-test2) (F=12.26, p=.000) in discomfort due to smell and 3.53+/-1.18(pre-test). 2.59+/-1.46(post-test1), 2.53+/-1.33(post-test2)(F=4.148, p=.025) in relation between age and smell. CONCLUSION: The results suggest that aroma-inhalation may have an effect on sleep, mood and smell and can be effective nursing intervention to increase the relaxation in stroke patients and their caregivers.
Aromatherapy* ; Caregivers* ; Depression* ; Humans ; Nursing ; Relaxation ; Smell* ; Stroke*