No abstract available.
Catalase ; Erythrocytes* ; Glutathione Peroxidase ; Humans ; Infant, Newborn* ; Superoxide Dismutase

No abstract available.
Anemia, Hemolytic, Autoimmune* ; Child* ; Hepatitis, Chronic* ; Humans

PURPOSE: Leptin, the product of the ob gene is primarily by adipose tissue but also by the human placenta. Leptin may also have a role as a regulator of fetal growth and development during normal pregnancy as well as in pregnancies associated with anomalous fetal growth. Our study aimed to discover whether or not leptin concentration in neonatal cord blood correlates with maternal disorder(preeclampsia, antenatal steroid). METHODS: Seventy newborns - twenty of preeclampsia, twenty of antenatal steroid treatment, ten of diabetes mellitus, twenty of neonatal asphyxia- and their mother were enrolled in this study. Gestational age, birth weight, length and placental weight were measured. Maternal age and weight were measured. Cord blood and maternal venous samples were collected and serum was separated and stored at -70dgreesC. Leptin was measured by radioimmunoassay. RESULTS: Neonatal cord leptin concentration was significantly elevated in infants whose mothers received antenatal steroid, preeclamptic mothers and diabetic mothers Also, neonatal cord leptin concentration was correlated with maternal serum leptin concentration in those maternal disorders. Cord blood leptin concentration in neonatal asphyxia group was significantly elevated, but wasn't significantly correlated with their maternal serum leptin concentration. CONCLUSION: Neonatal cord leptin concentration was significantly increased in mothers with preeclampsia, diabetes mellitus, and exposure of the antenatal steroid. We find that maternal disorders affected leptin concentration in cord blood, and that increased cord blood leptin in neonatal asphyxia was shown to be a product of fetus.
Adipose Tissue ; Asphyxia ; Birth Weight ; Diabetes Mellitus* ; Fetal Blood* ; Fetal Development ; Fetus ; Gestational Age ; Humans ; Infant ; Infant, Newborn ; Leptin* ; Maternal Age ; Mothers ; Placenta ; Pre-Eclampsia* ; Pregnancy ; Radioimmunoassay

No abstract available.
Hydranencephaly*

No abstract available.
Central Nervous System Infections* ; Central Nervous System*

No abstract available.

No abstract available.
Histiocytosis*

The diagnosis of congenital heart disease includes rare and diverse disorders. Children with congenital heart disease represent a growing population: The incidence of congenital heart defects is almost 1 in 100 live births, and of these, approximately 23 of 1000 newborns will require invasive treatment or will die as a consequence of their diagnosis by 1 year of age. Because of improved interventions, >1 million adults are now living with congenital heart disease. Selected congenital heart defects (or the process of their repair) lead to an increased risk for adult cardiovascular disease compared with the general population. Now we reviewed the methods of assessment for differential diagnosis of congenital heart diseases.
Adult ; Cardiovascular Diseases ; Child ; Diagnosis ; Diagnosis, Differential* ; Heart Defects, Congenital ; Heart Diseases* ; Heart* ; Humans ; Incidence ; Infant, Newborn ; Live Birth

VATER association of vertebral defects, imperforate anus, tracheoesophageal (T-E) fistula with esiphageal atresia, and radial and renal dysplasia are utilized to identify this complex. Other anomalies are vascular anomalies (cardiac defects and single umbilical artery), and prenatal and postnatal growth deficiency, defects of external genital and urinary tract as well as bone defects (preaxial lower extremity anomalies, supernumerary digits, rib anomaly). This pattern of malformation generally occurs sporadically in an otherwise normal family, and may occur as a part of a broader pattern, such as the trisomy 18, del (4p, 6q, and 13q) syndromes, and sirenomelia. As inversion of chromosome does not lose of genetic materials, phenotypic abnormalities does not occur. But rare cases have been reported. We report a neonate who had multiple congenital anomalies, including the VATER association defects associated with an unusual chromosomal abnormality, a paracentric inversion of chromosome 6 : 46, XY, .inv (6)(q11q16).
Anus, Imperforate ; Chromosome Aberrations ; Chromosomes, Human, Pair 6 ; Ectromelia ; Fistula ; Humans ; Infant, Newborn ; Lower Extremity ; Ribs ; Trisomy ; Urinary Tract

No abstract available.
Animals ; Pertussis Vaccine* ; Rats* ; Streptozocin* ; Whooping Cough*