1.A Case of Nevus Comedonicus Syndrome.
Korean Journal of Dermatology 2012;50(5):481-482
No abstract available.
Nevus
2.Drug Hypersensitivity Syndrome Associated Dapsone.
Korean Journal of Dermatology 2012;50(5):475-476
No abstract available.
Dapsone
;
Drug Hypersensitivity
3.Expression of Epidermal Growth Factor Receptor and Transforming Growth Factor-beta1 Type II Receptor in Oral Leukoplakia and Squamous Cell Carcinoma.
Tae Yeon KIM ; Jong In YOOK ; Jin KIM
Korean Journal of Pathology 1997;31(12):1247-1255
Growth stimulatory/inhibitory factors and their receptors are the important mediators of control of epithelial cell proliferation and differentiation. The aim of this study was to observe the distribution of epidermal growth factor receptor (EGFR) and transforming growth factor-beta1 type II receptor (TbetaRII) during carcinogenesis of oral squamous cell carcinoma (OSCC). Formalin fixed, paraffin embedded tissue from 25 oral leukoplakias (OL) and 15 OSCC was immunostained by avidin-biotin complex method. In OSCC, the carcinomatous area and the adjacent dysplastic/ hyperplastic area were examined. In OL, the hyperplasia and the epithelial dysplasia were examined. Monoclonal anti-EGFR Ab and polyclonal anti-TbetaRII Ab were applied. EGFR was mainly expressed in the basal layer and was increased with epithelial dysplasia in OL. TbetaRII was not detected in the basal cell layer and dysplastic area in OL. In contrast, the dysplastic area adjacent to OSCC showed positivity in the entire layer including the dysplastic area. In all cases of OSCC, both EGFR and TbetaRII showed positive reactions. EGFR was increased with the progression to the malignancy, and the expression pattern of TbetaR II was altered to be positive in the basal cell layer with progression to malignancy. These results suggest that the expression of EGFR appeared to be an early event and TbetaR II may be related to malignant transformation during oral carcinogenesis. The expression pattern of EGFR and TbetaR II may contribute to predict the risk of the development of carcinoma in oral premalignant lesions.
Carcinogenesis
;
Carcinoma, Squamous Cell*
;
Epidermal Growth Factor*
;
Epithelial Cells
;
Formaldehyde
;
Hyperplasia
;
Leukoplakia, Oral*
;
Paraffin
;
Receptor, Epidermal Growth Factor*
4.A Fifteen-year Epidemiological Study of Ventriculoperitoneal Shunt Infections in Pediatric Patients: A Single Center Experience.
Yeon Kyung KIM ; Hyung Jin SHIN ; Yae Jean KIM
Korean Journal of Pediatric Infectious Diseases 2012;19(3):141-148
PURPOSE: Ventriculoperitoneal (VP) shunt insertion is an important treatment modality in children with hydrocephalus. VP shunt infection is a major complication and an important factor that determines the surgery outcome. This 15-year study was performed to evaluate the epidemiology of VP shunt infections in pediatric patients treated at our center. METHODS: A retrospective review of medical records was performed in patients 18 years old or younger who underwent VP shunt insertion surgery from April 1995 to June 2010. RESULTS: Three hundred twenty-seven VP shunt surgeries were performed in a total of 190 pediatric patients (83 females, 107 males). The median age of the patients was 2.4 years (range, 0.02-17.9 years). Having a malignant brain tumor was the most frequent cause for VP shunt insertion. The shunt infection rate was 6.7% (22/327) per 100 operations and 9.5% (18/190) per 100 patients, and the incidence rate was 0.45 infection cases per 100 shunt operations-year. The most common pathogen was coagulase-negative staphylococcus (n=7) followed by methicillin resistant Staphylococcus aureus (n=1). Ten cases were treated with vancomycin and beta-lactam antibiotic (cephalosporin or carbapenem) combination therapy and 7 cases were treated with vancomycin monotherapy. The median duration of antibiotic treatment was 26 days (range, 7 to 58 days). Surgical intervention was performed in 18 cases (18/22, 81.8%). CONCLUSION: Epidemiologic information regarding VP shunt infections in pediatric patients is valuable that will help guide proper antibiotic management. Additional studies on the risk factors for developing VP shunt infections are also warranted.
Brain Neoplasms
;
Child
;
Epidemiologic Studies
;
Female
;
Humans
;
Hydrocephalus
;
Incidence
;
Medical Records
;
Methicillin Resistance
;
Retrospective Studies
;
Risk Factors
;
Staphylococcus
;
Staphylococcus aureus
;
Vancomycin
;
Ventriculoperitoneal Shunt
5.A Case of Dyskeratosis Congenita in a Woman.
Chi Yeon KIM ; Tae Heung KIM ; Tae Jin YOON
Korean Journal of Dermatology 2001;39(10):1162-1165
No abstract available.
Dyskeratosis Congenita*
;
Female
;
Humans
6.A clinical & statistical analysis of the facial bone fractures.
Jin Dong KIM ; Tae Yeon KIM ; Chun Eun CHUNG
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1992;19(1):38-47
No abstract available.
Facial Bones*
7.Comparison of Mycobactericidal Activity of 12 Kinds of Disinfectants for Mycobacterium chelonae.
Jin Mee HWANG ; Yeon Joon PARK ; So Yeon KIM ; Moon Won KANG ; Byung Kee KIM
Korean Journal of Nosocomial Infection Control 2000;5(1):1-8
BACKGROUND: Cleaning and disinfection of fiberoptic bronchoscope requires careful attention, especially to mycobacterium species because the contamination of mycobacteria could raise confusion on diagnosis. Recently, we detected contamination of Wydex(R) solution used in bronchoscope washer with Mycobacterium chelonae. In this study, we evaluated the mycobactericidal effect of 12 kinds of disinfectants for M. chelonae. METHOD: To evaluate the bactericidal effect of Wydex(R) 2%, Cidex(R) 2.25%, Cidex(R) 3%, Bacteriokiller (BK) disinfectant, Perasafe(R), HICLO-S(R), Lamicine(R), ethanol, Instrusept(R), Virkon(R), Betadine(R), and Vipon(R) against M. chelonae, culture was performed after exposure of two M. chelonae strains (ATCC 35749, the type strain and the strain isolated from contaminated Wydex(R) solution) to each disinfectant solution. The growth of organism was examined for up to 8 weeks. RESULTS: Growth of M. chelonae (reference strain of ATCC 35749 and isolated strain) was observed after a week incubation for Wydex(R) 2%, Cidex(R) (2.25%, 3%) and control. For BK disinfectant and Perasafe(R), they grew after 2-3 weeks, and 3-4 weeks, respectively. For HICLO-S(R) and Lamicine(R), only the contaminated strain grew after two and three weeks, respectively. For ethanol, Virkon(R), Betadine(R), Vipon(R), and Instrusept(R) , growth was not observed from either strain. CONCLUSIONS: On the basis of these results, Instrusept(R), virkon(R), ethanol, Betadine(R), and Vipon(R) were effective for the disinfection of M. chelonae. Especially, Instrusept(R) was thought to be useful as a disinfectant for bronchoscopes because it has advantages including non-corrosiveness, chemical stability, and non-irritativeness. And additional washing with ethanol might be effective. The finding that strain isolated from contaminated bronchoscopes was more resistant to disinfectants than reference strain suggested that the more resistant strains are selected throughout the improper disinfection.
Bronchoscopes
;
Diagnosis
;
Disinfectants*
;
Disinfection
;
Ethanol
;
Mycobacterium chelonae*
;
Mycobacterium*
8.Clinical study on necrotizing lymphadenitis.
Jee Yeon JANG ; Hyun Rim CHOI ; Jin Woo KIM
Journal of the Korean Academy of Family Medicine 1992;13(6):491-502
No abstract available.
Lymphadenitis*
9.Postirradiation malignant fibrous histiocytoma(MFH) of the oralmucosa: a case report.
Jong In YOOK ; So Yeon PARK ; Jin KIM ; Choong Kook YI
Journal of the Korean Association of Oral and Maxillofacial Surgeons 1991;17(3):29-33
No abstract available.
10.Postirradiation malignant fibrous histiocytoma(MFH) of the oralmucosa: a case report.
Jong In YOOK ; So Yeon PARK ; Jin KIM ; Choong Kook YI
Journal of the Korean Association of Oral and Maxillofacial Surgeons 1991;17(3):29-33
No abstract available.