Subcapsular hematoma of the liver in the neonate is an uncommon clinical presentation, although these tumors are frequently found upon perinatal autopsy. We describe the sonographic and MR findings of a subcapsular hematoma of the liver in a neonate having a clinical history of an inserted umbilical venous catheter, necrotizing enterocolitis and sepsis, and we also include a review of the relevant literature.
Autopsy ; Catheters ; Enterocolitis, Necrotizing ; Hematoma* ; Humans ; Infant, Newborn* ; Liver* ; Sepsis ; Ultrasonography

No abstract available.
DNA* ; Mycobacterium tuberculosis* ; Mycobacterium* ; Polymerase Chain Reaction*

No abstract available.
Poliomyelitis*

Microorganisms of conjunctival sac, lacrimal sac, and nasal cavity were studied in 86 patients with obstruction in the lacrimal system. We analyzed the data of bacteriologic culture and its antibiotic sensitivity. The results were as follows; 1. Staphylococcus epidermidis was the most common microorganism in conjunctival sac, lacrimal sac, and nasal cavity. 2. There was no correlation among the organisms in conjunctival sac, lacrimal sac, and nasal cavity. 3. Staphylococcus epidermidis and Staphylococcus aureus were most sensitive tocephalothin and cefatoxim.
Humans ; Nasal Cavity* ; Staphylococcus aureus ; Staphylococcus epidermidis

Cyclic guanosine monophosphate adenosine monophosphate (cGAMP) synthase (cGAS) detects human immunodeficiency virus (HIV) and produces cGAMP to induce cytokines. Reverse transcribed DNA of HIV is critical for triggering innate immune responses as inhibitor of HIV reverse transcriptase blocked the induction of interferon-beta by the virus. Furthermore, knockout of cGAS in human or mouse cell lines abrogated the production of cytokines by HIV infection highlighting the essential role of cGAS in detection of HIV and other retroviruses.
Adenosine Monophosphate ; Animals ; Cell Line ; Cytokines ; DNA ; Guanosine Monophosphate ; HIV Infections ; HIV Reverse Transcriptase ; HIV* ; Humans ; Immunity, Innate ; Interferon-beta ; Mice ; Retroviridae

Posturographic examination is commonly used by clinicians to evaluate standing balance. Because it is perfomed with double leg standing, it cannot sensitively detect the minor balance problem like functional ankle instability. This study aims to evaluate the test retest reliability of the single leg balance test using Tetrax posturography and its correlation with modified star excursion balance test (mSEBT). 30 healthy participants (16 male, 14 female, mean age 26.3+/-3.3) were volunteered for this study. We manufactured a specially designed wood plate to assess their single leg standing balance. It was set on each of the 4 force plates of Tetrax posturography (Sunlight Medical Ltd., Ramat Gan, Israel). Stability index were measured based on each single leg stance. Participants performed the single leg balance test on Tetrax posturography in three different times, and they also performed the mSEBT. The test retest reliability of stability index measured by Tetrax posturography was assessed by the intraclass correlation coefficient, and its correlation with the normalized composite distance of mSEBT was assessed by Pearson correlation coefficient. The single leg balance test using Tetrax posturography showed good test retest reliability. There was a negative correlation between the stability index of Tetrax posturography and the normalized composite distance of mSEBT, based on right and left leg stance, respectively. These findings suggest that Tetrax posturography is a useful and reliable tool for single leg balance assessment.
Ankle ; Ankle Injuries ; Female ; Humans ; Leg* ; Male ; Postural Balance ; Proprioception ; Wood

Cystic masses of the adrenal gland are unusual in the fetus and most are secondary to hemorrhage. Cysticneuroblastoma is extremely rare, and in contrast to solid neuroblastoma, follows a benign course, is diagnosedearlier, and rarely presents with metastatic lesions(1-4). We report one case of cystic neuroblastoma diagnosedprenatally by ultrasound(US) and magnetic resonance(MR) imaging, and include a review of the literature.
Adrenal Glands ; Fetus ; Hemorrhage ; Neuroblastoma*

Typhoid fever is a bacteremic disease and many organs, including intestine, liver, bone, lung, thyroid, kidney, spleen, heart and pancreas may be invaded by the organism. Acute pancreatitis associated with typhoid fever sometimes needs prolonged total parenteral hyperalimentation and antibiotic treatment. Systemic Candida infections are usually encountered as opportunistic infections in a setting of immunologic depression. The authors report a case of Candida parapsilosis fungemia associated parenteral nutrition in acute pancreatitis associated with typhoid fever. A 17 year-old man was transfered to Pusan national university hospital on May 4th, 1998 under diagnosis of salmonella sepsis. High fever, nausea, vomiting and diarrhea developed 10 days before entery. On admission, serum amylase, lipase and transaminase showed elevation. The patient was treated with antibiotics(ceftriaxon) and total parenteral hyperalimentation was done under diagnosis of acute pancreatitis and hepatitis associated with typhoid fever. On 3rd hospital day, body temperature returned to normal but abdominal pain, nausea and vomiting continued. On 18th hospital day, high fever recurred and ceftriaxon was re-administered. Three days later, body temperature returned to normal. On 25th hospital days, culture of blood and catheter tip was positive for C. parapsilosis. On 27th hospital days, sudden onset high fever, pnumonic infiltration, confusion, hypotension, oliguria and azotemia developed. On 34th hospital day, sudden onset ventricular fibillation developed. On 35th hospital day, the patients died. We report a case of candida fungemia in acute pancreatitis and hepatitis associated with typhoid fever.
Abdominal Pain ; Adolescent ; Amylases ; Azotemia ; Body Temperature ; Busan ; Candida* ; Catheters ; Ceftriaxone ; Depression ; Diagnosis ; Diarrhea ; Fever ; Fungemia* ; Heart ; Hepatitis* ; Humans ; Hypotension ; Intestines ; Kidney ; Lipase ; Liver ; Lung ; Nausea ; Oliguria ; Opportunistic Infections ; Pancreas ; Pancreatitis* ; Parenteral Nutrition ; Parenteral Nutrition, Total ; Salmonella ; Sepsis ; Spleen ; Thyroid Gland ; Typhoid Fever* ; Vomiting

Invasive fungal infection remains a major cause of morbidity and mortality in immunocompromised patients. Invasive fungal sinusitis can present as a Tolosa-Hunt syndrome (THS) or orbital apex, leading to frequent misdiagnosis. Accurate diagnosis of fungal infection invading the cavernous sinus or orbital apex is essential to reduce mortality through early antifungal treatment and reduce the risk of worsening with steroid treatment due to misdiagnosis of THS. Herein, we report a case of invasive fungal sinusitis mimicking THS.

PURPOSE: Cyclins, and their associated cyclin dependent kinases, regulate progression of the cell cycle through the G1 phase and into the S-phase during the DNA replication process. Cyclin E regulation is an important event in cell proliferation. Despite its importance, abnormalities of these genes and their protein products have yet to be found in lits asoociation with lung cancer. MATERIALS AND METHODS: The relationships between expression of cyclin A, cyclin B1, cyclin D1, cyclin D3, and cyclin E and clinicopathologic factors were investigated in 103 cases with non-small cell carcinomas, using immunohistochemical analysis. RESULTS: The positive immunoreactivity was observed in 51 cases (50%) for cyclin A, 33 cases (32%) for cyclin B1, 83 cases (81%) for cyclin D1, 19 cases (18%) for cyclin D3, and 11 cases (11%) for cyclin E. Expression of cyclin E was significant for lymph node metastasis (p=0.004, Chi-square test). There was no relationship between cyclin A, B1, D1, and E and histological typing, tumor size, lymph node metastasis, or pathological tumor, node and metastasis staging. CONCLUSION: These findings suggest that the expression of cyclin E played a role, to some degree, in the lymph node metastasis.
Adenocarcinoma ; Carcinoma, Squamous Cell ; Cell Cycle ; Cell Proliferation ; Cyclin A ; Cyclin B1 ; Cyclin D1 ; Cyclin D3 ; Cyclin E ; Cyclin-Dependent Kinases ; Cyclins ; DNA Replication ; G1 Phase ; Lung ; Lung Neoplasms ; Lymph Nodes ; Neoplasm Metastasis