1.Prevalence of Syphilis in Normal Population in Korea ( 1987 - 1991 ).
Yeon Sang CHOI ; Hee Joon YU ; Sook Ja SON
Korean Journal of Dermatology 1994;32(5):866-871
BACKGROUND: According to the areas and people that are examined, there are many differences in the prevalence of syphilis in Korea. However, the reactive rate of the serologi test for syphilis showed an increase in the 1960s, and it has deerea@sed from the beginning of the 1970s. OBJECTIVE: Comparing the results of tke serologic test for syphilis which lotad been performed for the 5 years(1987-1991) on the physical examines and pregnant women who were considered as healthy, with the results with normal people, who were considered as healthy, which had been already reported, we tried to observe the change of reactive rate of serologic test for syphili. METHODS: The serologic test for syphilis, including serum VDRL test and serum TPHA test, were carried out on 25,254 healthy adults(20,405 were physical examineea eamined at National Medical Center and 4,849 were pregnant women delivered at National Medical Cer ter). RESULTS: The reaetive rate of serum VDRL test was 0.8% in 25,25 the althy adults(physical examinees 0.8%, pregnant women 0.7%). There were no stistically differerces between the annual incidences. 85.5% of VDRL-reactive subjects showed low VDRL titers(below 1:4) by the quantitative serum VDRL test, The biologic false positive reaction of serum VDRL test was 29(19.5%) in 149 VDRL-reactive subjects, using serum TPHA test as a standard. CONCLUSION: This study suggested thai, there was a decrease in the prevslence of syphilis in Korea.
Asian Continental Ancestry Group
;
False Positive Reactions
;
Female
;
Humans
;
Incidence
;
Korea*
;
Pregnant Women
;
Prevalence*
;
Serologic Tests
;
Syphilis*
2.A Case of Bilateral Herprs Zoster.
Seung Yeon LEE ; Yeon Sang CHOI ; Hee Joon YU ; Sook Ja SON
Korean Journal of Dermatology 1994;32(6):1119-1122
Herpes zoster is characterized by several groups of vesicles situateu unilaterally within the distribution of the cranial or spinal nerve coming from one posterior ganglion Biateral involvement and recurrence are rare, and zoster involves two widely separated regions at on time are even rarer. We report a case of bilateral eupes zoster. A 5-years-old female patient was presented with painful bilateral grouped vesicles on an erythematous base along the dermatome of Lt T2 and Rt T5. Tzanck smear revealed multinucleated giant cells, and histopathologic findings were consistent with herpetic infection. She was successfully treated by administration of acyclovir without any significant cornplications.
Acyclovir
;
Female
;
Ganglion Cysts
;
Giant Cells
;
Herpes Zoster*
;
Humans
;
Recurrence
;
Spinal Nerves
3.Therapeutic Effect of Topical Ciclopiroxolamine on Onychomycosis.
Seung Yeon LEE ; Yeon Sang CHOI ; Hee Joon YU ; Sook Ja SON
Korean Journal of Dermatology 1995;33(3):504-509
BACKGROUND: Ciclopiroxole.minsolution or cream is the topical in imycotic agent which has been known to have the ability to penetrate the horny skin and nail keratin. OBJECTIVES: The purpose of this study was to evaluate the pierapeutic effect of 1% ciclopiroxolamine solution on onychomycosis. METHODS: 1% ciclopiroxolamie solution was applied topically to hentire surface of t,he diseased nail at least twice a day for 12 to 36 weeks according to the verity of nail involvement and degree of improvement in 21 cases of onychomycoses. RESULTS: 1. With only topical application of 1% ciclopiroxolamine solutior, 4 out of 21 cases(67%) showed 25% or more reduction of the affected nail area, and 8 out of 21 cases(38%) showed 50% or more reduction of the affected nail area. 2. There was no significant difference in the degree of improvem of according to the duration of disease. 3. Therapeutic effect was relat.ively high on Candida albicans, while it was relatively low on Aspergillus species. 4. 3 out of 7 cases of mild(up to 30%) involvement showed a 7% or more reduction of the affected nail, while 4 out of 6 cases of severe(60-100%) involvement showed a 25% or less reduction of the affected nail. 5. As side effects during the topical application of 1% ciclopiroxol nr ne solution, periungualer ythema appeared in 3 cases, and a burning sensation in 4 of 21 cases. CONCLUSION: 1% ciclopiroir olaniine solution could be tried as an effctive therapeutic agent on onychomycosis for the patient who would not be tolerable to oral an ifiigal medication for associated systemic diseases or who does not want oral medication.
Aspergillus
;
Burns
;
Candida albicans
;
Humans
;
Onychomycosis*
;
Sensation
;
Skin
4.Transthoracic-Extrapleural Approach for Microsurgical Thoracic Discectomy with Video Assistance: Technical Report of Three Cases.
Sang Ho LEE ; Sang Hyeop JEON ; Jong Yeul CHOI ; Ho Yeon LEE ; Byung Joo JUNG ; Sang Rak LIM
Journal of Korean Neurosurgical Society 2000;29(12):1677-1681
No abstract available.
Diskectomy*
5.A Case of Letterer: Siwe Disease.
Gun Yeon NA ; Sung Kwon CHOI ; Jae Bok JUN ; Sang Lip CHUNG
Korean Journal of Dermatology 1987;25(6):837-842
A 5-month-old male infantshowed greasy sealy papules on the scalp, dirty scaly papules on the trunk and scaly petechial papules on both the palms and soles since birth. When admitted to the hospital, the patient exhibited lymphadenopathy, hepatomegaly, abdominal distension, mild fever and skin eruption. The biopsy specimens from the skin and lymph node showed an infiltrate composed almost entirely of histiocytic cells with irregularly shaped nuclei and abundant, well demarcated cytoplasm. The histiocytic cells of the infiltrate were proved as Langerhans cells by electron microscopic examination and S-100 protein study. He was treated with methotrexate 30mg/m twice a week and prednisolone 40mg/m daily. Initially skin lesions and general condition were improved, but the patient expired. due to septicemia after 3 months.
Biopsy
;
Cytoplasm
;
Fever
;
Hepatomegaly
;
Humans
;
Infant
;
Langerhans Cells
;
Lymph Nodes
;
Lymphatic Diseases
;
Male
;
Methotrexate
;
Parturition
;
Prednisolone
;
S100 Proteins
;
Scalp
;
Sepsis
;
Skin
6.A Case of Prenatal Diagnosis of Congenital Fetal Goiter in Hyperthyroidism Mother.
Dong Han BAE ; Young Hwa KIM ; Kyu Yeon CHOI ; K T JANG ; Sang Yeob KIM
Korean Journal of Perinatology 1998;9(1):35-42
We report a case of prenatal diagnosis of fetal congenital goiter at 31weeks of gestation by ultrasonogram and fetal hypothyroidism confirmed at birth as thyroid function test by umbilical cord blood sampling. Maternal Graves' disease and the drugs used to treat hyperthyroidism in pregnant women can affect the fetus, causing hyperthyroidism or hypothyroidism and goiter. Fetal hypothyroidism may be caused by transplacental passage of either maternal thyrotropic-binding inhibitory immunoglobulin(TBII) antibodies or maternal treatment with propylthiouracil(PTU). Untreated fetal hypothyroidism may result in mental retardation, perceptual-motor, visual-spatial, and language developmental problems. In this article fetal thyroid function was not assessed by cordocentesis, but fetal congenital goiter was detected ultrasound. Ultrasound should be used to detect fetal goiter from 20 weeks onward. Fetal goiter should resolve when maternal PTU treatment is decreased. We have diagnosed fetal hypothyroidism in utero by ultrasonography. Significance of in utero management of fetal hypothyroidism is discussed.
Antibodies
;
Congenital Hypothyroidism
;
Cordocentesis
;
Female
;
Fetal Blood
;
Fetus
;
Goiter*
;
Graves Disease
;
Humans
;
Hyperthyroidism*
;
Hypothyroidism
;
Intellectual Disability
;
Language Development
;
Mothers*
;
Parturition
;
Pregnancy
;
Pregnant Women
;
Prenatal Diagnosis*
;
Thyroid Function Tests
;
Thyroid Gland
;
Ultrasonography
7.A Mycological Study on Dermatophytoses in Seoul During the Peroid 1985 - 1991.
Hee Joon YU ; Yeon Sang CHOI ; Young Gon BAIK ; Sook Ja SON
Korean Journal of Dermatology 1994;32(1):24-33
BACKGROUND: Dermatophytoses show marked differences in their incidences, distributions, and causative organisms by age, sex, occupations, environmental conditions and geographic distributions. OBJECTIVE: We evaluated the recent distributions of dermatophytes and compared them with the previous reports in Seoul. METHODS: We evaluated the incidences of dermatophytes according to the patient's age and sex, isolated month, and the infection sites with 387 strains of dermatophytes isolated from the various forms of dermatophytoses during the period from August 1985 to July 1991 in Seoul. RESULTS: T. rubrum was the most prevalent dermatophyte in all age groups except the first decade. The incidence of M. canis was high in age groups below 20 years old relatively high incidences of T. mentagrophytes and T. interdigitale in age groups over 30 years old. Dermatophytes were frequently isolated in summer season, but the incidence of M. canis was relatively high in October and December. T. rubrum was the most prevalent dermatophyte from all forms of dermatophytoses except tinea capitis, but the incidence of T. rubrum was relatively low in tinea corporis. The incidence of T. mentagrophytes was relatively high in tinea unguium and tinea manus, and M. canis was isolated only in tinea corporis and tinea capitis. From the cases showing more than two forms of dermatophytoses. T. rubrum was isolated for the most part. CONCLUSION: This study suggested that there was a rise in the cases of t. rubrum infections in Seoul and in recent years the prevalence of M. canis infections has markedly increased but those of E. floccosum and t. mentagrophytes have decreased.
Adult
;
Arthrodermataceae
;
Humans
;
Incidence
;
Occupations
;
Onychomycosis
;
Prevalence
;
Seasons
;
Seoul*
;
Tinea Capitis
;
Tinea*
;
Young Adult
8.Dexmedetomidine Use in Patients with 33degrees C Targeted Temperature Management: Focus on Bradycardia as an Adverse Effect.
Hyo Yeon SEO ; Byoung Joon OH ; Eun Jung PARK ; Young Gi MIN ; Sang Cheon CHOI
Korean Journal of Critical Care Medicine 2015;30(4):272-279
BACKGROUND: This study aimed to investigate bradycardia as an adverse effect after administration of dexmedetomidine during 33degrees C target temperature management. METHODS: A retrospective study was conducted on patients who underwent 33degrees C target temperature management in the emergency department during a 49-month study period. We collected data including age, sex, weight, diagnosis, bradycardia occurrence, target temperature management duration, sedative drug, and several clinical and laboratory results. We conducted logistic regression for an analysis of factors associated with bradycardia. RESULTS: A total of 68 patients were selected. Among them, 39 (57.4%) showed bradycardia, and 56 (82.4%) were treated with dexmedetomidine. The odds ratio for bradycardia in the carbon monoxide poisoning group compared to the cardiac arrest group and in patients with higher body weight were 7.448 (95% confidence interval [CI] 1.834-30.244, p = 0.005) and 1.058 (95% CI 1.002-1.123, p = 0.044), respectively. In the bradycardia with dexmedetomidine group, the infusion rate of dexmedetomidine was 0.41 +/- 0.15 microg/kg/h. Decisions of charged doctor's were 1) slowing infusion rate and 2) stopping infusion or administering atropine for bradycardia. No cases required cardiac pacing or worsened to asystole. CONCLUSIONS: Despite the frequent occurrence of bradycardia after administration of dexmedetomidine during 33degrees C target temperature management, bradycardia was completely recovered after reducing infusion rate or stopping infusion. However, reducing the infusion rate of dexmedetomidine lower than the standard maintenance dose could be necessary to prevent bradycardia from developing in patients with higher body weight or carbon monoxide poisoning during 33degrees C targeted temperature management.
Atropine
;
Body Weight
;
Bradycardia*
;
Carbon Monoxide Poisoning
;
Dexmedetomidine*
;
Diagnosis
;
Emergency Service, Hospital
;
Heart Arrest
;
Humans
;
Hypothermia, Induced
;
Logistic Models
;
Odds Ratio
;
Retrospective Studies
9.Cutaneous Infection by Fusarium solani in a Patient with Burger's Disease.
Hee Joon YU ; Soo Keun LEE ; Yeon Sang CHOI ; Sook Ja SON
Annals of Dermatology 1995;7(4):332-337
Fusarium species are known as ubiquitous soil saprophytes and human skin comtaminants. Occasionally, however, they have been reported to cause a variety of infections in humans. We report herein a case of cutaneous infection by Fusarium sokmi in a patient with Burger's disease involving his right lower leg. He was treated with itraconazole 200 mg p.o. per day for 5 weeks and the skin lesion resolved without any noticeable side effects. Furthermore, there has been no evidence of recurrence of the disease 9 months after discontinuing the itraconazole. This is the first reported case of cutaneous infection by Fusarium sokmi in a patient with Burger's disease and itraconazole was an effective drug in our case.
Fusarium*
;
Humans
;
Itraconazole
;
Leg
;
Recurrence
;
Skin
;
Soil
10.A case report of castleman disease in th neck: CT and MRI finding.
Sung Sik OH ; Yeon Ok LEE ; Young Chil CHOI ; Sang Sun LEE
Journal of the Korean Radiological Society 1993;29(3):385-387
Castlernan disease is a rare lymphoproliferative disorder of uncertain cause, which most commonly involves mediastinum and rarely affects retroperitoneal, axillary or cervical lymph nodes. Authors present CT the and MRI findings of a cases of Castleman disease involving cervical lymph nodes. On CT and MR. There were multiple lymph nodes enlargement with homogeneous enhancement along the bilateral internal jugular and spinal accessory lymph node chain.
Giant Lymph Node Hyperplasia*
;
Lymph Nodes
;
Lymphoproliferative Disorders
;
Magnetic Resonance Imaging*
;
Mediastinum
;
Neck*