1.Changes of Serum Tumor Necrosis Factor a and Interleukin 1B in the Sepsis of Neonates.
Mi Yeon LEE ; Yeon Kyun OH ; Ji hyun CHEY
Journal of the Korean Pediatric Society 1995;38(10):1307-1314
No abstract available.
Humans
;
Infant, Newborn*
;
Interleukins*
;
Sepsis*
;
Tumor Necrosis Factor-alpha*
2.Transcutaneous Oxygen and Carbon Dioxide Monitoring in Critically Ill Neonates.
Du Young CHOI ; Yong Kweon KIM ; Yeon Kyun OH
Journal of the Korean Pediatric Society 1990;33(9):1202-1208
No abstract available.
Carbon Dioxide*
;
Carbon*
;
Critical Illness*
;
Humans
;
Infant, Newborn*
;
Oxygen*
3.Statistical study on the incidence and mortality rate of low birth weight infant.
Sun Ae KANG ; Jae Kag CHOI ; Yeon Kyun OH
Journal of the Korean Pediatric Society 1992;35(12):1690-1695
No abstract available.
Humans
;
Incidence*
;
Infant, Low Birth Weight*
;
Infant, Newborn
;
Mortality*
;
Statistics as Topic*
4.A Clinical Observation of Neonatal Hyperbilirubinemia due to ABO Incompatibility.
Mi Jung KOH ; Young Kyun LEE ; Jin Hong PARK ; Yeon Kyun OH
Journal of the Korean Pediatric Society 1990;33(9):1194-1201
No abstract available.
Hyperbilirubinemia, Neonatal*
5.A Case of Wilson-Mikity Syndrome.
Jung Suk LEE ; Young Kyun LEE ; Hyang Suk YOON ; Yeon Kyun OH
Journal of the Korean Pediatric Society 1990;33(5):675-679
No abstract available.
6.Clinical analysis on newborn infants treated with mechanical ventilation.
Yeon Sim KIM ; Dae Ho CHOI ; Cheol Woo PARK ; Yeon Kyun OH
Journal of the Korean Pediatric Society 1991;34(10):1346-1355
No abstract available.
Humans
;
Infant, Newborn*
;
Respiration, Artificial*
7.Ultrasonographic Diagnosis by Pyloric Volume Measurement in Congenital Hypertrophic Pyloric Stenosis.
Soon Kil LEE ; Jae Wha OH ; Yeon Kyun OH ; Chang Guhn KIM
Journal of the Korean Pediatric Society 1994;37(11):1595-1599
Real-time ultrasonogram was performed in 31 Pt. with CHPS, who was admitted at the pediatric department of Wonkwang University hospital from January 1991 to June 1993. Those who had positive results of pyloric volume for diagnosis of CHPS and were confirmed by surgery. The results were at follows: 1) The average ultrasonographic measurements of pyloric muscle thickness, pyloric diameter, pyloric length were 4.9+/-1.09mm, 14.42+/-2.69mm, 19.17+/-2.37mm, and pyloric volume was 3.26+/-1.39ml. 2) The diagnostic reliabilities with the ultrasonographic measurements of muscle thickness (>4mm), pyloric diameter (>12mm) and pyloric length (>15mm) by Stunden's criteria in 31 cases were compared, which were not significant difference among them. 3) In ultrasonographic measurements of 31 cases for diagnosis of CHPS, positive results with 3 parameters were 80.6% and with 2 parameters and double tract signs were 87.1%. So. we conclude pyloric volume greater than 1.4ml was the most reliable parameter, which was satisfied 100% with diagnosis of CHPS.
Diagnosis*
;
Pyloric Stenosis, Hypertrophic*
;
Ultrasonography
8.A Case of Hereditary Spherocytosis.
Yeon Kyun OH ; Byeong Ho LEE ; Young Ha KIM ; Moon Ki CHO
Journal of the Korean Pediatric Society 1986;29(9):93-99
No abstract available.
9.A Case of Potter Syndrome Type I.
Jin Hong PARK ; Mi Jeong KOH ; Yeon Kyun OH ; Chan CHOI
Journal of the Korean Pediatric Society 1989;32(8):1150-1154
No abstract available.
10.The Effects of Glutamate Receptor Antagonists on Cultured Cerebral Cortical Neurons of Neonatal Mouse Damaged by Oxidative Stress.
Dae Ho CHOI ; Yeon Kyun OH ; Seung Taek PARK
Journal of the Korean Pediatric Society 1999;42(8):1096-1103
PURPOSE: To evaluate neurotoxic effects induced by oxygen-radicals, which were generated by adding xanthine oxidase(XO) and hypoxanthine(HX), and protective effects of glutamate receptor antagonist such as MK-801 and 6-cyano-7-nitroquinoxaline(CNQX). METHODS: Dissociated cell cultures were prepared from cerebrum of neonatal mouse. Tissues were dissected and diced into small pieces in phosphate buffered saline and were incubated at 37degrees C. Isolated cells were resuspended in Eagle's minimum essential medium and plated poly-L-lysine coated plastic coverslips in 96 well multichambers at a cell density of 3x105 cells/well. Cells were grown in a 5% CO2/95% air atmosphere at 37degrees C. Cytotoxic effects were examined in cerebral cortical neurons cultured for 3 hours in media containing various concentration of XO and HX. The protective effects of glutamate receptor antagonist were also examined by MTT assay and neurofilament enzymeimmunoassay(EIA). Microscopic examinations were also done. RESULTS: Oxygen radicals markedly induced decrement of the cell viability of cultured mouse cerebral cortical neurons in a dose-dependent manner. Midpoint cytotoxicity value was 30mU/ml XO/0.1mM HX, when mouse cerebral cortical neurons were incubated for 3 hours with various concentrations of XO and HX. The number of cells and neurites was decreased when cerebral cortical neurons were cultured for 3 hours in a medium containing 30mU/ml XO/0.1mM HX. MK- 801 was very effective in blocking oxidant-induced neurotoxicity, while CNQX falied to show any protective effect in these cultures. CONCLUSION: It is suggested that oxygen radicals are neurotoxic, and selective N-methyl-D-aspartate antagonists such as MK-801 are very effective in protecting neurotoxicity induced by oxygen radicals in cultured cerebral cortical neurons of neonatal mouse.
6-Cyano-7-nitroquinoxaline-2,3-dione
;
Animals
;
Anoxia
;
Atmosphere
;
Cell Count
;
Cell Culture Techniques
;
Cell Survival
;
Cerebrum
;
Dizocilpine Maleate
;
Excitatory Amino Acid Antagonists*
;
Glutamic Acid*
;
Ischemia
;
Mice*
;
N-Methylaspartate
;
Neurites
;
Neurons*
;
Oxidative Stress*
;
Plastics
;
Reactive Oxygen Species
;
Receptors, Glutamate*
;
Xanthine