To evaluate the health risk of the workplace environment of a general hospital toward the hospital workers, a questionnaire survey on the perception of risk at the workplace environment and environmental measurements at 27 locations with 240 workers in the hospital were made from October 25th, 1993 to October 30th, 1994. The results were as follows; 1. By the environmental measurements, 86 workers(36%) were found to be exposed to poor or harmful degree of general illumination, 193 workers(80%) were exposed to poor or harmful local illumination, 34 workers(14%) were exposed to poor or harmful degree of thermal condition and l80 workers(75%) were exposed to poor or harmful noise level, but nobody was exposed to poor or harmful dust and toluene concentration. Also nobody was exposed to poor or harmful level of radiation or anticancer/antibiotic agents. 2. The subjective perceptions on the environmental conditions felt by the workers were different from the objective findings by the environmental measurements. The workers underscored the poor illumination state and overscored the dust concentrations. Also workers oversensitized about the thermal condition, the noise level, the radiation level, the toluene concentration and anticancer/antibiotic agents. 3. The sources of noise were the dialogue(179 workers) and the office instruments(131workers). The sources of dust came from the clothes(108 workers) and the building materials(79 workers). 4. The questionnaire survey showed that the 28 workers were exposed to poor or harmful level of the antibiotics, 10 workers to alkali or acid and 6 workers to drug dust in the pharmacy but the above findings could not be proved by the environmental measurements.
Alkalies ; Anti-Bacterial Agents ; Dust ; Hospitals, General* ; Lighting ; Noise ; Pharmacy ; Surveys and Questionnaires ; Toluene

In this study, we distinguished urban and rural areas in Naju-si, Jeollanam-do, grasped the characteristics of those areas, and investigated the depression-related factors in Naju-si based on this. This study used Community Health Survey data from 2017 to 2019. To investigate the factors affecting the depression in Naju-si local residents, the odds ratio was calculated using a complex sample logistic regression model. As a result of confirming the factors affecting the prevalence of depression in Naju-si residents, the risk of depression was significantly higher at 1.59 (95% confidence interval [CI], 1.02–2.50) for women, 2.14 (95% CI, 1.20–3.83) for recipients of basic livelihoods, 2.35 (95% CI, 1.46–3.79) for those who did not practice walking, and 2.00 (95% CI, 1.23–3.26) for those who slept less than 5 hours. It is necessary to select high-risk groups as a regional-specific project to resolve the mental health disparities in Naju-si and to intervene in early depression prevention through support for mental health support services.

Objectives: The landscape of work environments has undergone rapid transformation in the wake of the COVID-19 pandemic. This study aims to identify oral health issues among mobile platform workers, analyze the risk factors within their working environment, and promote their oral health. Methods: A purposive sampling approach was employed to select fifteen participants, including replacement drivers, delivery drivers, and delivery couriers/messengers operating within Seoul’s mobile platform workforce. In-depth interviews were conducted between August and November 2023, with all sessions recorded and transcribed. Utilizing grounded theory methodology, data analysis progressed through stages of open coding, axial coding, and selective coding, ultimately leading to the construction of a paradigm model. Results: The majority of participants were male (93.3%), with an average age of 58.7 years. The paradigm model revealed low tooth brushing rates among mobile platform workers. This phenomenon was attributed to a poor brushing environment and a lack of willingness to brush, with the related context being the poor working environment. Intervention conditions included support for tooth brushing, oral health education, and oral examinations. Implementing an action-interaction strategy, which involves problem-solving pathways and a strong motivation to improve, resulted in improved tooth brushing rates. Conclusions To promote the oral health of mobile platform workers, it is essential to improve the environment for tooth brushing, particularly by increasing the availability of restrooms and related facilities as brushing spaces. Additionally, It is necessary to develop oral health policies and implement interventions based on an understanding of the working environment of mobile platform workers.

Recently, through the development of the primer extension preamplification(PEP) method which amplifies the whole genome, simultaneous multiple DNA analysis has become possible. Whole genome from each single cell can be amplified using 15 base oligonucleotide random primer. The greatest advantage of PEP-PCR is the ability to investigate several loci simultaneously and confirm results by analysing multiple aliquots for each locus. This technique led to the development of preimplantation genetic disease diagnosis using blastomere from early embryo, sperm, polar body and oocyte. In this study, we applied PEP-PCR in 20 cases of single amniocyte and 20 cases of single chorionic villus cell for the clinical application of the prenatal and preimplantational genetic diagnosis. We analysed 7 gene loci simultaneously which are 46, 47 exons related to dystrophin gene, two VNTR (variable number tandem repeat) markers using 5'toysIII, 3'CA related to dystrophin gene and DYZ1, DYZ3, DYS14 regions on chromosome Y. In all the tests, 97.5% of PEP-PCR amplifications with single cells were successful. We obtained 38/40 (95%) accuracy in gender determination through chromosome analysis comparison. Therefore, these results have significant implications for a sperm or oocyte analysis and prenatal or preimplantational genetic diagnosis.
Blastomeres ; Chorionic Villi ; Diagnosis ; DNA ; Dystrophin* ; Embryonic Structures ; Exons ; Genome ; Oocytes ; Polar Bodies ; Spermatozoa

We experienced a case of transient right-sided heart failure after angioplasty of membranous obstruction of the inferior vena cava confirmed by sonography and an inferior vena cavogram. Angioplasty involved the use of a self-expandable metallic stent, but after successful recanalization of the obstruction , the patient became dyspneic. Chest radiography revealed mild cardiomegaly with pulmonary congestion, but this was resolved spontaneously. For the prevention of serious heart failure, we recommend preprocedural evaluation of cardiac function.
Angioplasty* ; Cardiomegaly ; Estrogens, Conjugated (USP) ; Heart Failure* ; Humans ; Radiography ; Stents ; Thorax ; Vena Cava, Inferior*

OBJECTIVES: This study aimed to identify the effect of mental health on frequency of falls (single and recurrent falls) among elderly adults. METHODS: Data were drawn from the 2015 Korean Community Health Survey. A chi-square test was conducted to compare differences in fall frequency according to health-related behaviors, chronic diseases, and mental health. Subsequently, multinomial logistic regression analysis was used to identify the effects of mental health on single and recurrent falls based on variables found to be significant in the chi-square test. RESULTS: Recurrent falls were found to be more risky than single falls. Depression was significantly related to single falls (odds ratio [OR], 1.27; 95% confidence interval [CI], 1.12 to 1.44). Depression (OR, 1.56; 95% CI, 1.38 to 1.76), sleep disorder (5 hours or less: OR, 1.12; 95% CI, 1.02 to 1.23; more than 9 hours: OR, 1.24; 95% CI, 1.07 to 1.44, respectively), and subjective stress (OR, 2.30; 95% CI, 1.90 to 2.78) were significantly related to recurrent falls. CONCLUSIONS The study’s findings suggest that specialized fall prevention programs are needed to address different types of falls in elderly adults. To prevent recurrent falls, systematic treatment strategies and rehabilitation training must improve physical function and mental health.

OBJECTIVES: The objective of this study was to identify the factors associated with suicidal ideation among the elderly living alone received the elderly care service in a rural area. METHODS: This study was surveyed 206 the elderly living alone who received the elderly care service in G-gun, Jeollanamdo. The collected data were socio-demographic and health-related characteristics, family support and suicidal ideation. The used methods for statistical analysis were used t-test, analysis of variance, Pearson's correlational analysis and the multiple logistic regression analysis. RESULTS: In univariate analysis, the suicidal ideation of the elderly living alone was statistically significant associated with age, monthly income, sufficiency of sleeping, depression, stress, activities of daily living, instrumental activities of daily living, perceived health status and family support. As a result of multiple regression analysis, the associated factors with suicidal ideation were age, depression, stress and the activities of daily living. CONCLUSIONS: The suicidal ideation of the elderly living alone in the rural area was associated with age, mental health and independency of living. It will be needed the multidisciplinary approaches to prevent the suicidal ideation and attempts of the elderly living alone.
Activities of Daily Living ; Aged* ; Depression ; Family Characteristics ; Humans ; Jeollanam-do ; Logistic Models ; Mental Health ; Suicidal Ideation*

OBJECTIVES: This study aimed to identify the effect of mental health on frequency of falls (single and recurrent falls) among elderly adults. METHODS: Data were drawn from the 2015 Korean Community Health Survey. A chi-square test was conducted to compare differences in fall frequency according to health-related behaviors, chronic diseases, and mental health. Subsequently, multinomial logistic regression analysis was used to identify the effects of mental health on single and recurrent falls based on variables found to be significant in the chi-square test. RESULTS: Recurrent falls were found to be more risky than single falls. Depression was significantly related to single falls (odds ratio [OR], 1.27; 95% confidence interval [CI], 1.12 to 1.44). Depression (OR, 1.56; 95% CI, 1.38 to 1.76), sleep disorder (5 hours or less: OR, 1.12; 95% CI, 1.02 to 1.23; more than 9 hours: OR, 1.24; 95% CI, 1.07 to 1.44, respectively), and subjective stress (OR, 2.30; 95% CI, 1.90 to 2.78) were significantly related to recurrent falls. CONCLUSIONS The study’s findings suggest that specialized fall prevention programs are needed to address different types of falls in elderly adults. To prevent recurrent falls, systematic treatment strategies and rehabilitation training must improve physical function and mental health.

Masclura tricuspidata, also called as Cudrania tricuspidata, is one of the most common Moraceae family plants in East Asia. Its trivial name follows mulberry due to the similar morphology. Investigation of the bioactive constituents of M. tricuspidata leaves yielded a new xanthone derivative along with twenty known compounds through various chromatographic techniques. A new compound was defined as mascluraxanthone (3), a prenylated xanthone glucoside on the basis of 1D and 2D NMR and MS data. Twenty known compounds were identified as four xanthone derivatives (1-2 and 4-5), two flavans (6-7), six flavanol derivatives (8-13), a flavonone (14) and seven flavonol derivatives (15-21). Among the isolated compounds, flavanol and flavonoid derivatives with 3′,4′-OH groups showed antioxidant and anti-tyrosinase activities. Conclusively, the leaves of M.tricuspidata are rich in aromatic compounds including xanthones and flavonoids. In addition, these constituents showed antioxidant and anti-tyrosinase potentials, which might be useful for oxidative stress related diseases.

A 36-year-old pregnant woman was referred for amniocentesis at 19.5 weeks gestation because of advanced maternal age and evidence of increased risk for Edward syndrome in the maternal serum screening test. Cytogenetic analysis of the cultured amniotic fluid cells revealed mosaicism for ring chromosome 11: 46,XX,r(11)[65]/45,XX,-11[16]/46,XX[34]. Parental karyotypes were normal. A targeted ultrasound showed intrauterine growth restriction (IUGR). Cordocentesis was performed to characterize the ring chromosome and to rule out tissue specific mosaicism. Karyotype was confirmed as 46,XX,r(11) (p15.5q24.2)[229]/45,XX,-11[15]. And a few new form of ring were detected in this culture. The deletion of subtelomeric regions in the ring chromosome were detected by fluorescent in situ hybridization (FISH). The pregnancy was terminated. The fetal autopsy showed a growth-retarded female fetus with rocker bottom feet. We report a case of prenatally detected a de novo ring chromosome 11.
Pregnancy ; Female ; Humans