2.Delayed Non-arteritic Anterior Ischemic Optic Neuropathy Following Acute Primary Angle Closure.
Kyoung Nam KIM ; Chang Sik KIM ; Sung Bok LEE ; Yeon Hee LEE
Korean Journal of Ophthalmology 2015;29(3):209-211
No abstract available.
Female
;
Glaucoma, Angle-Closure/complications/surgery
;
Humans
;
Middle Aged
;
Optic Neuropathy, Ischemic/complications/*diagnosis
3.Delayed Non-arteritic Anterior Ischemic Optic Neuropathy Following Acute Primary Angle Closure.
Kyoung Nam KIM ; Chang Sik KIM ; Sung Bok LEE ; Yeon Hee LEE
Korean Journal of Ophthalmology 2015;29(3):209-211
No abstract available.
Female
;
Glaucoma, Angle-Closure/complications/surgery
;
Humans
;
Middle Aged
;
Optic Neuropathy, Ischemic/complications/*diagnosis
4.The effect of aging on red blood cell memobrane lipid peroxidation in diabetic patients.
Hyung Joon YOO ; Sung Hee IHM ; Byung Tae KIM ; Yeon Bok CHANG ; Moon Gi CHOI ; Sung Woo PARK
Journal of Korean Society of Endocrinology 1993;8(3):281-286
No abstract available.
Aging*
;
Erythrocytes*
;
Humans
;
Lipid Peroxidation*
5.A report of two cases of mucoepidermoid carcinoma.
Joon Hee KIM ; Yong Bok KIM ; Chul Soo KIM ; Dong Soon KIM ; Re Hwe KIM ; Chang Ho KIM ; Yeon Lim SUH
Tuberculosis and Respiratory Diseases 1993;40(1):58-66
No abstract available.
Carcinoma, Mucoepidermoid*
6.The sustaining effect of three polymers on the release of chlorhexidine from a controlled release drug device for root canal disinfection.
Young Bin BOK ; Doug Youn LEE ; Chang Young LEE ; Kyung Nam KIM ; Kee Yeon KUM
Journal of Korean Academy of Conservative Dentistry 2004;29(6):548-554
The aim of this in vitro study was to evaluate the suitability of using chitosan, poly (lactide-co-glycolide) (PLGA), and polymethyl methacrylate (PMMA) to control the release of chlorhexidine digluconate (CHX) from a prototype of controlled release drug device (CRD) for root canal disinfection. Four different prototypes with different formulations were prepared. Group A (n = 12); The device (absorbent paper point) was loaded with CHX as control. Group B (n = 12); same as group A, but the device was coated with chitosan. In Groups C and D, the device was treated in the same way as group A and then coated three times with 5% PMMA (Group C, n = 12), or coated three times with 3% PLGA (Group D, n = 12). The devices were randomly allocated to experimental groups of 12 each. All CRD prototypes were soaked in 3 mL distilled water. The concentrations of CHX were determined using a UV spectrophotometer. The surface characteristics of each prototype were observed using a scanning electron microscope. The result showed that release rate of CHX was the greatest in the non-coated group, followed by the chitosan-coated group, the PLGA-coated group, and the PMMA-coated group (P < 0.05). Pores were observed on the surface of the prototypes that were coated with PLGA and PMMA. When the pore size was smaller, the release rate was lower. This data indicate that polymer coating can control the release rate of CHX from the CRD prototypes.
Chitosan
;
Chlorhexidine*
;
Dental Pulp Cavity*
;
Disinfection*
;
Polymers*
;
Polymethyl Methacrylate
;
Water
7.Internal Carotid Artery Aneurysm Presenting with Unilateral Nasal Hemianopsia.
Kyoung Nam KIM ; Chang Sik KIM ; Yeon Hee LEE ; Sung Bok LEE
Journal of the Korean Ophthalmological Society 2014;55(9):1406-1411
PURPOSE: To report a case of unilateral nasal hemianopsia caused by a large internal carotid artery aneurysm. CASE SUMMARY: A 56-year-old female presented with large cupping in the left optic nerve head detected incidentally during a routine check-up. She had no underlying systemic disease except hypertension. The best corrected visual acuity was 20/20 in both eyes and a slit-lamp examination showed no abnormal findings. Ophthalmoscopy showed cup/disc ratios of 0.6 in the right eye and 0.75 in the left eye. Relative afferent papillary defect or color vision defect was not observed. A Humphrey visual-field test indicated unilateral nasal hemianopsia in the left eye. Brain CT and angiography revealed a large 2.2-cm aneurysm on the left internal carotid artery. CONCLUSIONS: Internal carotid artery aneurysm should be considered as a possible cause of unilateral nasal hemianopsia in patients without intraocular lesion.
Aneurysm*
;
Angiography
;
Brain
;
Carotid Artery, Internal*
;
Color Vision Defects
;
Female
;
Hemianopsia*
;
Humans
;
Hypertension
;
Middle Aged
;
Ophthalmoscopy
;
Optic Disk
;
Visual Acuity
8.Effect of Visual Information by Ultrasound on Maternal-Fetal Attachment.
Jee Young LEE ; Jeong Yeon CHO ; Soon Bok CHANG ; Ju Hyun PARK ; Young Ho LEE
Korean Journal of Women Health Nursing 2002;8(3):335-344
Providing visual information about the fetus to the mother by the ultrasound examination was found to be an effective nursing intervention to promote Maternal-Fetal Attachment. In keeping with the purpose of the study, to evaluate the effect of providing visual information by ultrasound on level of Maternal-Fetal Attachment, a non-equivalent experimental group quasi-experimental design was used. The data were collected using Cranley's Maternal-Fetal Attachment Scale(1981) with a research questionnaire that consisted of 16 items on general characteristics and 23 items on Maternal-Fetal Attachment from November 2, 2000 to August 11, 2001. Subjects were 126 pregnant women who were received visual information by ultrasound and 123 pregnant women who did not receive visual information by ultrasound after finishing examination. The data were analyzed by using the SPSS/PC+ window 10.0 version program. The results of this study were as follows: There was no statistical difference in general characteristics between both groups. The scores on Maternal-Fetal Attachment at second trimester show no statistical difference (t=1.123, p=0.263). The scores on Maternal- Fetal Attachment in both groups increased between the second trimester and third trimester. However, the increase was greater in the group receiving visual information by ultrasound as compared to the group which did not receive the visual information(t=-2.152, p=0.032). This result shows that providing visual information about the fetus by the ultrasound examination is effective in increasing Maternal-Fetal Attachment.
Female
;
Fetus
;
Humans
;
Mothers
;
Nursing
;
Pregnancy
;
Pregnancy Trimester, Second
;
Pregnancy Trimester, Third
;
Pregnant Women
;
Surveys and Questionnaires
;
Ultrasonography*
9.A Case of Pulmonary Alveolar Proteinosis that Improved with GM-CSF Inhalation Therapy.
Bok Soon CHANG ; Jungwon NOH ; Chang Soo OK ; Ga Yeon LEE ; Seo Young SOHN ; Sunha BAHNG ; Man Pyo CHUNG
Korean Journal of Medicine 2011;80(5):588-594
Pulmonary alveolar proteinosis (PAP) is a rare condition that is treated using whole lung lavage. A recent study suggested that granulocyte-macrophage colony stimulating factor (GM-CSF) plays roles in both the pathogenesis and treatment of PAP. We present a 69-year-old man with PAP who deteriorated despite bilateral whole lung lavage; that said, his symptoms, chest X-ray findings, and pulmonary function test improved after GM-CSF inhalation therapy over 12 months. GM-CSF therapy is an effective treatment modality for PAP.
Aged
;
Bronchoalveolar Lavage
;
Colony-Stimulating Factors
;
Granulocyte-Macrophage Colony-Stimulating Factor
;
Humans
;
Inhalation
;
Lung
;
Pulmonary Alveolar Proteinosis
;
Respiratory Function Tests
;
Respiratory Therapy
;
Thorax
10.Esculetin inhibits N-methyl-D-aspartate neurotoxicity via glutathione preservation in primary cortical cultures.
Chang Ryul LEE ; Eun Joo SHIN ; Hyoung Chun KIM ; Yeon Sik CHOI ; Taekyun SHIN ; Myung Bok WIE
Laboratory Animal Research 2011;27(3):259-263
Recently, loss of endogenous glutathione during N-methyl-D-aspartate (NMDA) receptor-mediated excitotoxic injury, and the resultant overproduction of reactive oxygen species (ROS) through an arachidonic acid cascade process in brain, have been implicated in neuronal damage in various neurodegenerative diseases. Glutathione depletion induced by L-buthionine-(S,R)-sulfoximine (BSO), an inhibitor of glutathione synthesis, is known to cause arachidonic acid-mediated excitotoxicity in primary mixed cortical cultures. The aim of this study was to investigate whether esculetin (6,7-dihydroxycoumarin), an inhibitor of lipoxygenase, protects against neurotoxicity induced by NMDA or BSO. We observed that neurotoxicity induced by NMDA but not kainic acid was attenuated by esculetin. At the same concentration (100 microM), esculetin attenuated the 45Ca2+ uptake elevation induced by NMDA. Free radical-mediated neuronal injury induced by H2O2 and xanthine/xanthine oxidase was concentration-dependently blocked by esculetin. Esculetin (1-30 microM) dose-dependently inhibited BSO-induced neuronal injury. In addition, arachidonate-induced neurotoxicity was completely blocked by esculetin. BSO also reduced glutathione peroxidase (GPx) activity, but did not change glutathione reductase (GR) activity 24 h after treatment. Esculetin dose-dependently increased GR activity, but did not alter GPx activity. These findings suggest that esculetin can contribute to the rescue of neuronal cells from NMDA neurotoxicity and that this protective effect occurs partly through NMDA receptor modulation and the sparing of glutathione depletion.
Arachidonic Acid
;
Brain
;
Glutathione
;
Glutathione Reductase
;
Kainic Acid
;
Lipoxygenase
;
N-Methylaspartate
;
Neurodegenerative Diseases
;
Neurons
;
Oxidoreductases
;
Peroxidase
;
Reactive Oxygen Species
;
Umbelliferones