1.Emergency arteriography in extremity trauma
Yeo Sub LIM ; Hyun Sub JUNG ; See Sung CHOI ; Young Sun CHUNG ; Chahng Guhn KIM ; Jong Jin WON
Journal of the Korean Radiological Society 1986;22(5):767-771
The emergency arteriography have been performed in a total of 13 patiens with extermity trauma, including 9fractures, 3 blunting traumas, and 1 penetrating injury. over 17 months period. The indications were as follows:absent or diminishe pulse, swelling, sensory or motor deficit , and hypotension. Patients with an absent pulse,the most reliable indication of arterial injury, should have immediate arteriography. The superficial femoralartery was commonly injured especially with distal femoral shaft fracture. The most common arteriographic findingswas arterial occlusion.
Angiography
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Emergencies
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Extremities
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Humans
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Hypotension
2.Performance Evaluation of the QXDx BCR-ABL %IS Droplet Digital PCR Assay
Hee Jung CHUNG ; Mina HUR ; Sumi YOON ; Keumrock HWANG ; Hwan Sub LIM ; Hanah KIM ; Hee Won MOON ; Yeo Min YUN
Annals of Laboratory Medicine 2020;40(1):72-75
Accurate detection of BCR-ABL fusion transcripts at and below molecular response (MR) 4 (0.01% International Scale [IS]) is required for disease monitoring in patients with chronic myeloid leukemia (CML). We evaluated the analytical performance of the QXDx BCR-ABL %IS (Bio-Rad, Hercules, CA, USA) droplet digital PCR (ddPCR) assay, which is the first commercially available ddPCR-based in vitro diagnostics product. In precision analysis, the %CV was 9.3% and 3.0%, with mean values of 0.031% IS and 9.4% IS, respectively. The assay was linear in the first order, ranging from 0.032% IS to 20% IS. The manufacturer-claimed limit of blank, limit of detection, and limit of quantification were verified successfully. There was a very strong correlation between the results of the QXDx BCR-ABL %IS ddPCR assay and the ipsogen BCR-ABL1 Mbcr IS-MMR (Qiagen, Hilden, Germany) real-time quantitative PCR assay (r=0.996). In conclusion, the QXDx BCR-ABL %IS ddPCR assay can provide reliable results for CML patients.