1.Some characteristics of subtype HIV-1 in the south of Vietnam
Journal of Medical Research 1998;6(2):34-37
The subtypes of HIV-1 from 106 HIV infected persons were determined by using the nested PCR method. Some results might be drawn: the HIV-1 samples from 83% of the investigated persons were E subtypes. The coexistence of B- and E- subtypes were observed in 8 out of 106 examined patients (7.6%). Non E- non B subtypes HIV-1 were also shown in 5.7% of the studied subjects. 40% of the newborns of mothers suffered from HIV-1 infection were infected. Their HIV-1 were all E-subtypes.
HIV-1
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HIV Infections
2.Observing of the progression of HIV infected intravenous drug users in Hochiminh city (1995-1997)
Journal of Medical Research 2000;11(1):13-18
Preliminary survey on some parameters of immune system (humoral & cellular immunity) of 74 persons who were HIV (-) addicts in HCM city was carried out on the concentrations of immunoglobuline (Ig)/serum, Mantoux test, count of lymphocytes, T-CD4, T CD8, the result indicated that there were reduction of T-CD4 number in HIV(-) addicts, dysfunction of humoral and cellular immune in the HIV infected addicts during disease progressing. The time of progression of HIV/AIDS - IDU is rather short in this stage and the mortality rate after the first year of AIDS in HCM city was high. Further studies are necessary.
HIV
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HIV Infections
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Immune System
3.Determination of household direct costs in treatment of Shigellosis in Nha Trang, Khanh Hoa province
Yen Thi Bach Nguyen ; Thien Dinh Duong ; Dung Viet Truong ; Canh Gia Do ; Giang Bao Kim ; Thang Huu Nguyen ; Diep Bich Pham
Journal of Medical Research 2008;55(3):115-121
Background: Shigella-induced diarrhea has been considered a major health problem leading to high morbidity and mortality. This disease can lead to dire consequences; however, the true burden of the disease, including the costs and sequalae associated with shigellosis is not yet known. Objectives: (1) To describe the health seeking behavior and the way of payment of population when suffering Shigella; (2) To identify and analyze the direct household costs associated with the treatment of diarrhea due to Shigella. Subjects and method: 290 patients of all ages with positive Shigella diarrhea admitted to public health facilities in Nha Trang, Khanh Hoa province in the period from August 2002 to January 2004 were included in the study. The subjects were divided into three age groups, the first 0-5, second 5-18 and the last one was over 18 years old. Patients and their relatives were interviewed at three stages - day 7, day 14 and day 90 - to obtain all the required information. Results: 134 of 290 patients (47%) paid for using the other health care services before admission to the study\u2019s facilities. The average direct cost per episode for the patients at group aged 0-5 was 129,000 VND, group aged 6-18 was 59,267 VND and over 18 years old was 173,531 VND; it was 131.960 VND for three groups. Comparison with the average household expenditure for health care, it was higher in the poorer group and it was lower three times than the richest group. The average direct medical cost per episode was higher the average direct non-medical cost per episode for all groups. Conclusions: The average direct cost per episode of Shigellosis treatment was rather high especially the average direct cost for the treatment at the health facility. It was also high compared with the average expenditure for health per capita so that it becomes large economic burden for households.
Direct cost
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Shigella
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treatment
4.Study on the effective control of postpreal blood glucose of resistant starch cakes in patients with type 2 diabetes
Huu Dung TRAN ; Quang Hung LE ; Bao Dung VO ; Hoang Vu NGUYEN ; Thanh Bao Yen LUONG ; That Hy TON ; Phuoc Hieu DOAN ; Thi Bich Hien PHAM ; Huu Tien NGUYEN ; Hai Thuy NGUYEN
Hue Journal of Medicine and Pharmacy 2023;13(7):52-58
Background: This study was conducted on 93 volunteers with type 2 diabetes to investigate the ability of acetylated wheat starch cake containing 32.1% resistant starch to control postprandial blood glucose levels. Material and methods: The study was designed using a crossover, double-blind trial method. During each testing day, after a minimum of 12 hours of overnight fasting, each participant consumed two identical cakes containing either 80 g of acetylated wheat starch or 80 g natural wheat starch with 330ml of water within 15 minutes. Blood glucose levels were measured at baseline, 60 mins (G1), and 120 mins (G2) after ingestion. The predictive value of factors that contribute to the ability of resistant starch to control postprandial blood glucose was determined by the area under the receiver operating characteristic (ROC) curve based on the combined effect of the cake weight-to-BMI ratio (g/m²BMI) and HbA1c. Results: 60 mins and 120 mins postprandial capillary glucose levels after consuming acetylated wheat starch cake (10.4 ± 1.2 và 9.2 ± 1.2 mmol/L, respectively) were significantly lower compared with natural wheat starch cake (13.3 ± 1.8 và 11.2 ± 1.8 mmol/L, respectively) (p < 0.05). For good control of postprandial blood glucose levels, a maximum of 80 g of acetylated wheat starch can be used per serving for patients with type 2 diabetes with HbA1c ≤ 7.25 without blood glucose-lowering medication is required. Conclusion: acetylated wheat starch has better ontroled of postprandial blood glucose compared with natural wheat starch in patients with type 2 diabetes. This is very suitable in the processing of diets including resistant starch for patients with type 2 diabetes for the purpose of both supporting treatment and improving quality of life.