1.The clinical application of comprehensive treatment and prognosis guide in children with febrile seizures caused by upper respiratory infections
Chinese Journal of Primary Medicine and Pharmacy 2014;21(18):2729-2730
Objective To investigate the effect of comprehensive treatment and prognosis guide in children with febrile seizures caused by upper respiratory infections.Methods 58 cases of children with febrile seizures caused by upper respiratory infections were divided into the two groups using a random number table method,and the control group received routine first aid and treatment,while the observation group took comprehensive treatment and prognosis guide.The clinical efficacy and recurrence were compared.Results The observation group's abatement of fever time,seizures disappear time and average length of stay was (30.15 ±2.78)h,(4.25 ±0.63)d and (6.51 ±0.52) d,which were significantly less than those of the control group [(45.43 ± 3.14) h,(7.11 ± 0.72) d and (10.02 ± 0.67) d] (t =10.21,9.62,10.30,all P < 0.05) ; The observation group's relapse rate was 13.79% after treatment,significantly lower than 31.03 % of the control group (x2 =11.23,P < 0.05).Conclusion The comprehensive treatment combined with prognosis guide has significant effect in the treatment of children with febrile seizures caused by upper respiratory infections,which can significantly improve clinical symptoms,reduce relapse after treatment.So it has a better clinical value.
2.Application of Multimedia Technique Binding Interconnection Network in Surgery Medical Teaching
Chinese Journal of Medical Education Research 2006;0(08):-
This paper has introduced the application of multimedia technique binding interconnection network in surgery medical teaching.The level of teaching and administration in surgery medical teaching have been highly raised by making manufacture medical multimedia courseware,setting up the routes of Chinese-English languages information query and internal-international academic communication,building up the systems of surgery medical test,daily administration and learning in Web.
3.Design on Evaluation Index System of Teaching Quality in Military Medical Universities
Chinese Journal of Medical Education Research 2003;0(04):-
By adopting the Delphi index and AHP,the evaluation standard,index design and allocation of index are studied and discussed,which has strengthened the scientificity and measurability of the index system.
4.Comparative study on the effects of suspension and pillow elevation on limb swelling after elbow surgery
Lingyun MO ; Guiling PENG ; Yejun ZHA
Modern Clinical Nursing 2013;(11):49-50
Objective To compare the clinic effects of suspension and pillow elevation on limb swelling after elbow surgery. Methods One hundred patients receiving operations on elbow fracture were randomly divided into experiment group(suspension elevation)and the control group(pillow elevation)to eliminate limb swelling,50 cases in each group.The forearm circumference(10 cm below elbow)were measured 1-5d after operation,the circumferences on the first day and the fifth day recorded for comparing effects of the limb swelling elimination.Results The circumferences on the 1st day and 5th day of the suspension elevation group and the pillow elevation group were(2?53±0?76)cm,and(4?19±2?36)cm,respectively.The differences in circumference between the two groups were statistically significant(P<0?05).Conclusion The suspension elevation is more effective in promoting venous circulation and eliminating swelling,so it is conducive for the elbow fracture patients in early functional exercise?
5.Treatment of the old terrible triad of the elbow without operative history
Yejun ZHA ; Xieyuan JIANG ; Maoqi GONG
Journal of Peking University(Health Sciences) 2016;48(2):224-229
Objective:To introduce the surgical techniques and treating results of the old “terrible triad”of the elbow.Methods:A retrospective analysis of 1 1 cases of old “terrible triad”of the elbow treated by the author from March 2009 to February 2014 were performed,with 9 males and 2 females;mean age was (31.82 ±8.66)years (17-45 years).The average time after injury was (6.36 ±2.50) weeks (4-12 weeks),with 7 cases on the left and 4 right.The combined injury included 2 cases with distal radius fractures,1 with ankle fractures,fractures of the distal radius and the head injury (minor epidural hematoma,no surgery),and 1 with Pilon fractures and L4 fractures (fixed at local hospital). All the patients had elbow stiffness and joint dislocation,and 2 patients had symptoms of ulnar nerve. Mason classification of radial head fractures:2 cases were type Ⅰ,5 were type Ⅱ,4 were type Ⅲ. Classification of the coronoid process:Regan &Morrey:1 was type Ⅰ,10 were type Ⅱ;according to O’Driscoll classification,all the fractures were tip fracture,one was the first subtype,10 were the second subtype.The elbow were released,the coronoid process were fixed by lasso suture combined with Kirschner wires.Radial head fractures were resected in 1 case,and replaced in 1 case,3 cases with no
treatment,6 cases with osteotomy and 3.0 mm headless compression screw (HCS)fixation.The lateral collateral ligament complex and the common extensor tendon were repaired to the humeral lateral epicon-dyles,No.2 Ethibon was used in 2 cases through bone holes,and suture anchorsin the other 9 cases.All the patients were fixed by Stryker DJDⅡhinged external fixator to protect the bone and soft tissue.Re-sults:The average follow-up time was (38.36 ±21.92)months (19-77 months).All the patients had no obvious pain,instability and ulnar nerve symptoms in the last follow-up.The average elbow flexion was 134.09°±12.41°(100°-140°),average extension was -15.91°±14.46°(-40°-0°),range of flexion and extension was 118.18°±23.80°(70°-140°).Average pronation was 70.91°±26.63° (20°-90°),supination was 70.91°±26.63°(20°-100°).The range of motion (ROM)of forearm rotation was 150.91°±43.00°(40°-180°).Average Mayo elbow performance score (MEPS)was 96.36 ±5.04 (85 -100).X-ray showed that no degenerative changes.Five patients had heterotopic os-sifications,according to Hastings and Graham grading:1 case was grade Ⅰ,3 cases were grade ⅡA, 1 case was ⅡB.Conclusion:The old “terrible triad”of elbow with no operative history is difficult to treat.The elbow’s functions and stabilization can be recovered by thorough elbow release,repair of coro-noid process and anterior capsule,radial head fractures,lateral collateral ligament and the common ex-tensor tendon insertion,combined with hinged external fixator.Joint stiffness and heterotopic ossification are common complications.
6.The Protective Effects of Polypeptides from Chlamys farreri against UVB Radiation
Yejun YU ; Xiaoping LIU ; Chunbo WANG
Chinese Journal of Dermatology 1994;0(05):-
Objective To study the protective effects of th e polypeptides isolated from Chlamys farreri(PCF)against ultraviolet B radiatins.Methods An oxidative damage model of HeLa epi thelial cell line irradiated by ultraviolet B(UVB 7.15?10 -5 J /cm 2 )was established.The HeLa cells were randomly divided into six groups:control group,UVB radiated groups(radiated control,0.5%PCF,1%PCF,2%PCF,1%Vit C).The enzymic activities of HeLa cells were tested by MTT methods,the apoptosis rate an d death rate of HeLa epithelial cells and the content of free calcium in those cells were tested by using flow cytometry(FCM).The contents of MDA and the activities of GSH-Px ,SOD,CAT in the supernatants of cells were determin ed by biochemical methods.Results The results indicated that polypept ides fromChlamys farreri could enhance the activities of GSH-Px,SOD,CA T and decrease the contents of MDAin the su pernatants of HeLa cells,increase t he concentration of cellular free calciumin the cells,and decrease the rates of apoptosis and cell death of the cells .Conclusions The PCF has the protective effects on the HeLa cells irradiated by ultraviolet B.The mechanism of th is effects of PCF may be mediated by e-liminating the free radicals,by increasing the activities of antioxidative enzymes to inhibit the oxidativ e damages caused by UVB .
7.Effects of Mycobacterium Phlei on Funcitonal States of Th_1/Th_2 in Patients with COPD and Preventive Effects on AECOPD
Haiping HUANG ; Jun WU ; Yejun YIN
Chinese Journal of Pharmacoepidemiology 2007;0(02):-
Objective:To investigate the effects of Mycobacterium Phlei on functional states of Th_1/Th_2 in patients with chronic obstructive pulmonary disease(COPD),and clinical effects on the prevention of acute exacerbation of chronic obstructive pulmonary diseases(AECOPD).Method:60 patients with COPD of gradeⅡwere randomly divided into a treatment group and controlled group.The controlled group were given a routine therapy,while the treatment group were given utilins in addition to the routine treatment.The contents of?-interferon(IFN-?) and interleukin-4(IL-4) in their peripheral blood and their clinical efficacy were observed before and after the treatment.Result:Before and after the treatment, IFN-?/IL-4 ratio in the treatment group was 1.39?0.20 and 1.94?0.31 respectively(P
8.Comparison of two surgical approaches used in elbow arthrolysis
Yejun ZHA ; Xieyuan JIANG ; Manyi WANG
Chinese Journal of Orthopaedic Trauma 2010;12(6):542-547
Objective To compare the posterior midline approach and the combined lateral and medial approach usually used in elbow arthrolysis. Methods From January to December in 2009, 41 cases of elbow stiffness were treated and fully followed up by the same team in our hospital. The posterior midline approach was used in 21 cases, 15 males and 6 females, with an average age of 35.8 years (16 to 70 years). In this group, the total flexion-extension arc was < 30° in 12 cases, 31° to 60° in 7 cases, and 61° to 90° in 2 cases. Eight cases had ulnar symptoms. The combined lateral and medial approach was applied in 20 cases, 8 males and 12 females, with an average age of 38. 8 years (16 to 51 years). In this group, the total flexion-extension arc was < 30° in 11 cases, 31° to 60° in 7 cases, and 61° to 90° in 2 cases. Five cases had ulnar symptoms. Results The 41 cases were followed up for 4 to 15 months (average, 7.9 months). In the posterior approach group, the mean preoperative flexion-extension ROM (27.6°± 25.7°) was improved to the postoperative 111.4°± 25.6°, the mean preoperative rotation ROM ( 152.9°± 46. 9°) to the postoperative 168.1°± 19. 1°, and the mean preoperative MEPS score (65.5 ± 11.5) to the postoperative 95.7 ±6.4. In the combined approach group, the mean flexion-extension ROM was improved from 35.5°± 25.0° preoperatively to 116. 5°± 19.1° postoperatively, the mean rotation ROM from 138.0°±55.7° preoperatively to 148.5°± 45.6° postoperatively, and the mean MEPS score from 66. 3 ± 13.0 preoperatively to 97.3 ± 7.0 postoperatively. The differences were statistically significant between preoperation and postoperation in both groups ( P < 0. 05), but not statistically different between the 2 groups in the preoperative or postoperative values ( P > 0. 05). In the posterior approach group, 5 patients had huge hematoma, 3 had wound dehiscence at the posterior elbow, and the others all had mild hematoma. But in the combined approach group, no wound complications were noted. Conclusion The combined lateral and medial approach should be used as far as possible in the elbow arthrolysis to avoid the likely complications when the posterior midline approach is used.
9.Diagnosis and treatment of the missed adolescent humeral capitellar fracture
Yejun ZHA ; Xieyuan JIANG ; Maoqi GONG
International Journal of Surgery 2015;42(11):743-748,封3
Objective To introduce the diagnosis and treatment of the missed adolescent humeral capitellar fracture malunion.Methods Retrospectively analyzed 6 cases with missed adolescent capitellar fracture malunion treated by the author from Jul.2010 to Mar.2015 and their follow-up results.Among them, 5 were male and 1 was female.The average age is (14.33 ± 1.86) years, 4 were left-side and 2 were right.Results The average time from injury to the operation is (8.67 ± 3.88) months.Before operation, the average elbow flexion was (91.67° ±7.53°), the average elbow extension was (40.0° ± 8.94°), the average range of flexion and extension activities was (51.67° ±11.69°).Forearm rotation was not limited.Average M EPS score was (80.83 ± 4.92).Released the elbow in 3 cases with additional medial incision.The fragment was fixed by HCS.The lateral collateral ligament was repaired by suture anchors (2 cases) or by trans-os suture(4 cases).Three cases were fixed by DJDⅡ Stryker hinged external fixatorswhich were removed after 8 weeks.The average postoperative follow-up time was (39.33 ± 20.42) months.Postoperatively, the average elbow flexion was (138.33° ±7.528°), the average elbow extension was (5.0° ± 4.472°), the average range of flexion and extension activities was (133.33° ±9.832°).Forearm rotation is not limited.The average MEPS score was 100.Conclusions The adolescent capitellar fracture is prone to be missed and cause malunion, elbow stiffness or other complications which is very difficult to deal with.By complete elbow release, osteotomy and internal fixation, the lateral collateral ligament repair, and hinged external fixator if necessary, the final elbow function can be improved.
10.Radial nerve injury secondary to use of hinged elbow external fixators
Maoqi GONG ; Yin ZHU ; Yejun ZHA ; Ting LI ; Xieyuan JIANG
Chinese Journal of Trauma 2013;(5):411-415
Objective To discuss causes and treatment outcomes of radial nerve injury related to hinged external fixators applied to the elbow,enhance understanding of the injury and thereby reduce its clinical incidence.Methods The study involved five cases who experienced radial nerve injury in the wake of application of unilateral hinged external fixators to the elbow.Exploration and neurolysis was perfomed at 3-12 weeks after injury since no signs of nerve recovery.Afterwards,follow-up was made for all cases.Results Causes of radial nerve injury were as follows:proximal humerus Schanz screws stretched and compressed radial nerve by tethering soft tissues into cicatricial bands in two cases; distal humerus Schanz screws compressed radial nerve by tethering soft tissues adjacent to radial nerve to cicatricial bands in one case; distal humerus Schanz screws compressed radial nerve in motion of the elbow by tethering thickened intermuscular septa and further forcing the enlargement of muscle force in two cases.Forces of muscles supplied by radius nerve reached fourth or fifth rank at postoperative one-year follow-up.Conclusions Radial nerve is vulnerable in the application of unilateral hinged external fixators to the elbow due to its special path and relative stability.Accordingly,injury to radial nerve can be reduced and even avoided by knowing its anatomy features and standardizing the operation in use of external fixators.Exploration and treatment immediately after the confirmation of radial nerve injury can achieve good prognosis.