1.A Comparison of Side for Termination, and Continuation Rate for Various Kinds of Oral Contraceptive Pill.
Sung Kwan LEE ; Doo Hie KIM ; Min Hae YEH ; Soon Ho HONG
Korean Journal of Preventive Medicine 1970;3(1):51-96
No abstract available.
2.Hair diameter measurement methods: micrometer caliper versus phototrichogram
Jae Hyun PARK ; Yeh Hong HO ; Kotchamol MANONUKUL
Archives of Aesthetic Plastic Surgery 2023;29(2):97-101
Background:
Hair diameter is a crucial element in deciding the treatment and predicting the prognosis of hair transplantation in patients with hair loss.
Methods:
Ten female volunteers participated in this study. Three sites at different horizontal positions of the scalp were chosen for measurement: midoccipital, mastoid, and temporal. Three boxes of 1 cm2 were marked from superior to inferior along the midline of each site, and five anagen hairs ≥10 cm long were randomly sampled from each box. The thickness of each collected hair was measured at three positions along the hair length: 1 cm, 5 cm, and 10 cm from the surface of the skin. The diameters of the hairs were measured using a micrometer caliper and a Folliscope phototrichogram, and the measurements were compared.
Results:
The average thickness of all hairs was 76.90±12.29 μm when measured with the caliper and 108.78±19.97 μm when measured with the phototrichogram. There was a statistically significant difference between the two measurement methods (P<0.001). The average hair thickness from the three areas (midoccipital, mastoid, and temporal) showed a significant difference between the caliper and the Folliscope hair measurements (P<0.001): midoccipital area (caliper, 74.46±9.71 μm; Folliscope, 109.03±19.59 μm), mastoid area (caliper, 76.36±10.67 μm; Folliscope, 103.73±18.67 μm), and temporal area (caliper, 79.89±15.18 μm; Folliscope, 113.59±20.43 μm).
Conclusions
Measuring hair thickness using a phototrichogram, which generates a measurement of the long-axis dimension, is clinically useful in the treatment of patients with hair loss and patients undergoing hair transplantation.
3.Intramuscular gentamicin improves the efficacy of ciprofloxacin as an antibiotic prophylaxis for transrectal prostate biopsy.
Henry S S HO ; Lay Guat NG ; Yeh Hong TAN ; Mavis YEO ; Christopher W S CHENG
Annals of the Academy of Medicine, Singapore 2009;38(3):212-216
INTRODUCTIONInfection-related complications after transrectal ultrasound guided prostatic biopsy (TRPB) could be life threatening. Our centre observed sepsis after TRPB despite prophylactic oral ciprofloxacin. We reviewed all cases of post-TRPB sepsis with their bacteriology and evaluated if the addition of intramuscular (I/M) gentamicin to standard prophylaxis before TRPB could reduce its incidence.
MATERIALS AND METHODSIn a single urological centre, we performed an interventional study that compared a prospective group with retrospective control. The latter is known as the "cipro-only" group included consecutive patients who underwent TRPB between 1 September 2003 and 31 August 2004. The addition of I/M gentamicin 80 mg half an hour before TRPB started on 1 September 2004. All subsequent patients who underwent TRPB until 31 August 2005 were included in the "cipro+genta" group. Patients who did not receive the studied antibiotics were excluded.
RESULTSThere were 374 patients in the "cipro+genta" group and 367 patients in the "cipro-only" group with comparable profiles. There were 12 cases of post-TRPB sepsis in the "cipro-only" group and 5 cases in the "cipro+genta" group. Ciprofloxacin-resistant Escherichia coli (E. coli) was the only pathogen isolated in both groups. In the "cipro-only" group, 9 patients had positive blood cultures and 8 were sensitive to gentamicin. In the "cipro+genta" group, the only positive E. coli was gentamicin-resistant. One patient in the "cipro+genta" group was admitted to the intensive care unit with septicaemia.
CONCLUSIONThe addition of I/M gentamicin to oral ciprofloxacin is a safe and effective prophylactic antibiotic regime in reducing the incidence of post-TRPB sepsis.
Administration, Oral ; Adult ; Aged ; Antibiotic Prophylaxis ; methods ; Biopsy ; Ciprofloxacin ; administration & dosage ; therapeutic use ; Drug Resistance, Bacterial ; Escherichia coli ; drug effects ; isolation & purification ; Gentamicins ; administration & dosage ; Humans ; Injections, Intramuscular ; Male ; Middle Aged ; Prospective Studies ; Prostate ; diagnostic imaging ; pathology ; Rectum ; Ultrasonography
4.Tamoxifen and the Risk of Parkinson's Disease in Female Patients with Breast Cancer in Asian People: A Nationwide Population-Based Study.
Chien Tai HONG ; Lung CHAN ; Chaur Jong HU ; Chien Min LIN ; Chien Yeh HSU ; Ming Chin LIN
Journal of Breast Cancer 2017;20(4):356-360
PURPOSE: Whether tamoxifen affects the risk of neurodegenerative disease is controversial. This nationwide population-based study investigated the risk of Parkinson's disease (PD) associated with tamoxifen treatment in female patients with breast cancer using Taiwan's National Health Insurance Research Database. METHODS: A total of 5,185 and 5,592 female patients with breast cancer who did and did not, respectively, receive tamoxifen treatment between 2000 and 2009 were included in the study. Patients who subsequently developed PD were identified. A Cox proportional hazards model was used to compare the risk of PD between the aforementioned groups. RESULTS: Tamoxifen did not significantly increase the crude rate of developing PD in female patients with breast cancer (tamoxifen group, 16/5,169; non-tamoxifen group, 11/5,581; p=0.246). Tamoxifen did not significantly increase the adjusted hazard ratio (aHR) for subsequently developing PD (aHR, 1.310; 95% confidence interval [CI], 0.605–2.837; p=0.494). However, tamoxifen significantly increased the risk of PD among patients followed up for more than 6 years (aHR, 2.435; 95% CI, 1.008–5.882; p=0.048). CONCLUSION: Tamoxifen treatment may increase the risk of PD in Taiwanese female patients with breast cancer more than 6 years after the initiation of treatment.
Asian Continental Ancestry Group*
;
Breast Neoplasms*
;
Breast*
;
Female*
;
Humans
;
National Health Programs
;
Neurodegenerative Diseases
;
Parkinson Disease*
;
Proportional Hazards Models
;
Tamoxifen*
5.F508 amino acid deletion mutation of CFTR gene in Korean lung cancer patients.
Yun Young JUNG ; Hong Il HA ; Soon Hee JUNG ; Min Goo LEE ; Hyean Woo LEE ; Joon Ho YOON ; Jong Whan CHOI ; Byung Il YEH
Experimental & Molecular Medicine 2001;33(1):29-31
Mutations of the transmembrane conductance regulator (CFTR) gene in cystic fibrosis lead to dysfunction of the lung, pancreas, and sweat glands, etc. To investigate the possibility of the relationship between lung cancer and the mutations of CFTR gene, we determined amino acid sequences using reverse transcription-polymerase chain reaction (RT-PCR) and DNA sequencing. In this study, the deletion mutation of 508th amino acid in one of nine lung caner patients was found confirming that CFTR gene mutation exists in a Korean lung cancer patient.
Adult
;
Aged
;
Cystic Fibrosis Transmembrane Conductance Regulator/*genetics
;
Female
;
Human
;
Korea
;
Lung Neoplasms/*genetics
;
Male
;
Middle Age
;
*Sequence Deletion
;
Support, Non-U.S. Gov't
6.Thirty Years of Bone Marrow Transplantation in the Singapore General Hospital.
Colin PHIPPS ; Aloysius Yl HO ; Yeh Ching LINN ; Sathish GOPALAKRISHNAN ; Ai Leen ANG ; Jing Jing LEE ; Hong Yen NG ; Francesca Wi LIM ; Priscilla Sm GOH ; Yvonne Sm LOH ; Patrick Hc TAN ; Liang Piu KOH ; Mickey Bc KOH ; Lai Heng LEE ; Yeow Tee GOH ; Yong Wan ONG ; William Yk HWANG
Annals of the Academy of Medicine, Singapore 2016;45(7):315-317
Bone Marrow Transplantation
;
history
;
methods
;
HLA Antigens
;
immunology
;
Hematopoietic Stem Cell Transplantation
;
history
;
methods
;
History, 20th Century
;
History, 21st Century
;
Hospitals, General
;
Humans
;
Peripheral Blood Stem Cell Transplantation
;
history
;
methods
;
Singapore
;
Transplantation Conditioning
;
history
;
methods