Objective To study the therapeutic effects of acupuncture therapy for prevent pain of replantation of severed finger. Methods Totals of 80 patients were randomly divided into two groups from March 2012 to March 2014. Patients in the treatment group were treated with acupuncture therapy, and patients in the control group were treated with routine care. Results The pain scores of 4, 6, 12, 24 and 48 hours after the treatment in the treatment group were (2. 13 ± 0. 33), (2. 75 ± 0. 67), (3. 25 ± 0. 59), (3. 43 ± 0. 78) and (2.85 ±0.62), which were significantly lower than those in the control group (t =2. 421, 2. 270, 7. 223, 7. 614, 4. 106, respectively;P<0. 05). In the treatment group, one case had vascular crisis, with an incidence of 2. 5%. In the control group, four cases had vascular crisis, with an incidence of 15. 0%, there was a significant difference between the two groups (χ2 =2. 165,P<0. 05). One case in the treatment group had diclofenac sodium suppositories, with an incidence of 2. 5%. While seven cases had diclofenac sodium suppositories, with an incidence of 17. 5% in the control group, there was a significant difference between the two groups (χ2 =2. 287,P<0. 05). Conclusions Acupuncture therapy can significantly reduce postoperative pain and reduce the incidence of vascular crisis, it is worthy of promotion.