1.Combined Use of Traditional Chinese and Western Medicine for Chronic Pelvic Inflammatory Diseases: A Meta-analysis
Minghui FAN ; Fengli ZHANG ; Ye REN
Acta Medicinae Universitatis Scientiae et Technologiae Huazhong 2010;39(1):127-129
Objective To evaluate the clinical effectiveness of combined use of traditional Chinese and Western medicine for chronic pelvic inflammatory diseases.Methods By searching in the major databases of CNKI,ISI Web of Knowledge,VIP Information and Pubmed,we collected data of randomized controlled trials pertaining to combined use of traditional Chinese and Western medicine in the treatment of chronic pelvic inflammatory diseases.Results Twenty-five randomized controlled trials involving totally 3081 patients were collected according to the inclusion criteria,and meta-analysis of the data indicated that combined use of traditional Chinese and Western medicine can be of great value in the management of chronic pelvic inflammatory diseases in comparison with exclusive use of Western medicine [combined odds ratio(OR)was 3.20 with 95% confidence interval(CI)(2.74,3.73),Z=14.85,P<0.01].Conclusion The clinical evidence derived from the analysis suggests that the combination of traditional Chinese and Western medicine for chronic pelvic inflammatory diseases can be effective with good security.
2.The effects of radiation-induced heart injury on cardiac troponin I and endothelin-1 and the preventive and therapeutic effect of fluvastatin
Fengyun FAN ; Bingfang ZHANG ; Jiangfeng YE
Medical Journal of Chinese People's Liberation Army 1983;0(05):-
Objective To investigate the effect of radiation-induced heart injury on cardiac troponin I (cTnI)and endothelin-1(ET-1) and observe the preventive and therapeutic effect of fluvastatin. Methods Healthy female SD rats were randomly divided into three groups: control group(c), irradiation alone group(R) and fluvastatin therapeutic group (F). Rats of F group had been gastrogavaged with fluvastatin at dose of 20mg?kg -1?d -1 from 1week before irradiation to the end of the experiment. In C group and R group, rats were gastrogavaged with the same volume isotonic sodium chloride. The rats of R and F group were irradiated with accelerator linear at a dose of 20Gy thoracically. Rats were executed at 5,15,30d and 60d after irradiation, then cTnI in serum and ET-1 in blood plasma were detected. Results On 5d, the content of cTnI in R group increased significantly than that in C group(P
3.Ameliorated piggyback liver transplantation
Qiuyan ZHANG ; Lin FAN ; Qifa YE
Chinese Journal of Hepatobiliary Surgery 2015;21(4):278-280
Classical piggyback liver transplantation (CPBLT) is an advanced technique based on standard orthotopic liver transplantation (SOLT),which has more advantages compared to the SOLT.However,there are still some problems with CPBLT to be solved,such as complicated surgical procedures,postoperative hepatic venous outflow obstruction and thrombosis.Recently,in order to solve these problems,modifications have been made,being named ameliorated piggyback liver transplantation (APBLT).The APBLT solved above-mentioned problems,and expanded the application of PBLT.Therefore,this article describes the technique of these ameliorations,and discusses their individual characteristics.
4.Causes of Conversions to Open Surgery in Patients Receiving Gynecological Laparoscopic Operations:Report of 45 Cases
Xuemei FAN ; Qiushi ZHANG ; Ming YE
Chinese Journal of Minimally Invasive Surgery 2005;0(07):-
Objective To study the causes of conversion to open surgery in patients receiving gynecological laparoscopic operations. Methods From January 2002 to December 2007,totally 2630 patients received gynecological laparoscopy in our hospital; 45 of them were converted to open surgery. The data of the 45 cases were analyzed. Results The causes of conversion to open surgery included uterus myoma located at specific locations (25 cases,55.6%),severe pelvic-abdominal adhesion (10 cases,22.2%),uterine horn pregnancy (3 cases,6.7%),ovarian tumors (3 cases,6.7%),surgical injury (3 cases,6.7%) ,and adenomyoma with requirement for uterus conservation (1 case,2.2%). Conclusions Peculiar locations of uterine myoma and severe pelvic-abdominal adhesion are the main causes of conversion to open surgery during gynecological laparoscopy. Detailed preoperative evaluation can decrease the rate of the conversion rate. Right timing of the conversion may reduce complication rate.
5.A new steroidal glycoside from Lygodium japonicum
Leihong ZHANG ; Chunlin FAN ; Xiantao ZHANG ; Zhiqi YIN ; Wencai YE
Journal of China Pharmaceutical University 2006;(6):491-493
To investigate the chemical constituents from the aerial parts of Lygodium japonicum. Methods:Various chromatographic techniques were employed for isolation and purification of the constituents. The structures were elucidated by chemical evidence and spectral methods. Results:A new stigmasterol glycoside,(24R)-stigmastan-3β,5α,6β-triol 3-O-β-D-glucopyranoside (1),together with three known phenolic glycosides:6-O-p-coumaroyl-D-glucopyranose (2),6-O-caffeoyl-D-glucopyranose (3),1-O-(E)-caffeoyl-β-D-gentiobiose (4) were obtained and identified by spectroscopic methods. Conclusion:All compounds were isolated from Lygodiaceae for the first time.
6.Alkaloids from the leaves of Nauclea officinalis
Long FAN ; Chunlin FAN ; Ying WANG ; Xiaoqi ZHANG ; Qingwen ZHANG ; Junqing ZHANG ; Wencai YE
Acta Pharmaceutica Sinica 2010;45(6):747-51
To study chemical constituents of the leaves of Nauclea officinalis, eight alkaloids were isolated from 95% ethanol extract by various chromatographic methods. The structures were elucidated on the basis of spectroscopic data (IR, UV, ESI-MS, 1D and 2D NMR) and identified as naucleactonin C (1), strictosamide (2), vincosamide (3), pumiloside (4), angustoline (5), angustine (6), 18, 19-dihydroangustine (7) and naucleofficine D (8). Compound 1 is a new indole alkaloid. Compounds 6 and 7 were isolated from this plant for the first time.
7.Discussion on Research and Development for Chinese Ethnic Medicine Products
Ciren LABA ; Dan ZHANG ; Fan YE ; Tingting KUANG ; Xianrong LAI
Chinese Journal of Information on Traditional Chinese Medicine 2015;(1):1-4
Ethnic medicine is an important component of traditional Chinese medicine and excellent traditional culture. New products of ethnic medicine are important application form to play therapeutic advantages of ethnic medicine, whose research and development should focus on the maintenance of characteristics of ethnic medicine. From the perspective of the research and development of ethnic medicine, this article discussed research ideas in the development of new products of ethnic medicine and put forward that attention should be paid to the experience on using the ethnic medicine, related literature studies, and ethnic medicine resource protection and utilization as well. In addition, this article put forward the research tactics in new products of ethnic medicine, such as medicinal materials, effective parts, active ingredients, the secondary development research and so on, with a purpose of improving the level of researching and developing new products of ethnic medicine.
8.Investigation of administration mechanism for science and technology development in university: in chance of the inplement of national major projects for science and technology
Ruiquan FAN ; Liheng ZHANG ; Rufei YE ; Peng WEI
Chinese Journal of Medical Science Research Management 2012;(6):389-390
In this paper,practice of major projects inplement in some universities was summarized.Also,the question of how to promote the innovation of science and technology system and establish a proper administration mechanism for science and technology in university was discussed,with the purpose of providing a reference frame for the department of science and technogoly in university.
9.Correlation of oxidized low-density lipoprotein and lectin-like oxidized low-density lipoprotein receptor-1 with pre-eclampsia
Fan ZHANG ; Yuanhua YE ; Wei PENG ; Fing ZHAN
Chinese Journal of Obstetrics and Gynecology 2009;44(2):94-98
Objective To investigate the role of oxidized low-density lipoprotein (oxLDL) and lectin-like oxidized low-density lipoprotein receptor-1 (LOX-I) in pre-ecalmpsia. Methods From June 2007 to January 2008,73 women with pre-eelampsia who delivered in the Department of Obstetrics, Affiliated Hospital of Qingdao University Medical College,were recruited, including 35 women with mild pre-eclampsia (MPE group) and 38 women with severe pre-eclampsia(SPE group). And 45 healthy pregnant women were taken as control group. Enzyme-linked immunosorbent assay (ELISA) was used to measure the plasma concentrations of oxLDL in these women. Semiquantitative RT-PCR and Western blot were used to investigate the expression of LOX-1 mRNA and protein in placenta. The expression of caspase-3 mRNA in placenta was determined using Semiquantitative RT-PCR. Results (1) The plasma concentrations of oxLDL in MPE group ( 0.42 ± 0.11 ) mg/L, SPE group ( 0.68 ± 0.12 ) mg/L, were significantly higher compared with control group (0.35 ± 0.14 )mg/L( P < 0.01 ) and the concentrations of oxLDL in MPE group were significantly higher compared with SPE group (P<0.01 ). (2) The expression of LOX-1 mRNA in placenta of MPE group(0.70 ±0.10) and SPE group(0.84 ±0.08) were significantly higher than that in control group(0.58 ± 0.11 ) ( P<0.01 ) and the expression of LOX-1 mRNA in MPE group was significantly higher than that of SPE group (P<0.01 ). (3) The expression of LOX-1 protein in placenta of MPE group (0.79±0.15 )and SPE group(0.90±0.12) were significantly higher compared with control group(0.68 ±0.11)( P<0.01 ), while the expression of LOX-1 protein of MPE group was significantly higher compared with SPE group (P <0.01 ). (4) The expression of caspase-3 mRNA in placenta of MPE group(3.82± 0.18) and SPE group(5.39±0.14) were significantly higher than that in control group(2.19±0.20) (P <0.01 ), and the expression of caspase-3 mRNA in MPE group was significantly higher than that of SPE group (P<0.01 ). (5) In pre-eclampsia groups, the levels of LOX-1 mRNA in placenta were positively correlated with the plasma concentrations of ox LDL ( r=0.93, P<0.05 ), and caspase-3 mRNA expression were positively correlated with the expression of LOX-1 mRNA in placenta( r=0.84, P<0.05). Conclusion Increased levels of oxLDL in plasma may induce excess expression of LOX-1 in placenta, which may be involved in the pathophysiological processes of pre-eclampsia.
10.A method for impedance measurements based on EEG acquisition system.
Jilun YE ; Lanlan WEI ; Fan WANG ; Yantao SONG ; Xu ZHANG
Chinese Journal of Medical Instrumentation 2014;38(4):240-250
In the bioelectric measurement, the electrode impedance detection is an important index to the signal quality evaluation and sensor electrode contact condition. In this paper, a method of accurately measuring the electrode impedance based on EEG measurement system was put forward, the method is based on the constant current source excitation signals which are added to the human body, by monitoring the human voltage to measure the electrode impedance. And different reference resistor calibration calculation in different sections was used to reduce the effect of constant current source on the precision of measurement results to improve the measurement accuracy.
Calibration
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Electric Impedance
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Electroencephalography