Anti-Bacterial Agents ; pharmacology ; Child ; Dyspepsia ; drug therapy ; Erythromycin ; analogs & derivatives ; pharmacology ; therapeutic use ; Gastroesophageal Reflux ; drug therapy ; Gastrointestinal Motility ; drug effects ; Humans ; Motilin ; pharmacology ; Receptors, Gastrointestinal Hormone ; drug effects ; Receptors, Neuropeptide ; drug effects

Objective To investigate the different expression of NF-κB p65 Protein in placental tissues between premature delivery and term delivery and to explore the significance of nuclear factor kB (NF-κB) protein expression in preterm delivery. Methods Fifty premature delivery pregnant women and thirty term delivery pregnant women ( were enrolled in this study. According to the way of delivery , the patients were divided into two groups. The expression of NF-κB p65 protein was analyzed by using immunohistochemistry method in the placental tissues. Results In the term delivery, NF-κB p65 was mainly negative or weak positive expressed in the cytoplasm of cells in the placental tissues. There was no demonstrable difference in immunostaining of the NF-kB p65 subunit in the placental tissues including chorion, umbilical cord and fetal membranes before and after labor ( P ＞ 0.05 ). In the premature delivery, NF-κB p65 was strongly expressed in the cytoplasm and nuclear of cells. The expression of NF-κB p65 protein in chorion and fetal membranes from premature delivery( 18% ,56% ) was significantly higher than that from normal pregnant women (6.7% ,13.3%, P ＜0.01 ). But no significant change was found for NF-κB p65 expression in umbilical cord in pregnant women with or without premature delivery ( P ＞ 0.05 ). And in fetal membranes and deciduas, there was a significant increase in the staining of immunoreactive NF-κB p65 in preterm(52.9% ,58.8% ) by caesarean section compared to tissues obtained from term delivery( 13.3%,6.7%, P ＜0.01 ). In chorion and fetal membranes, there was significant increases in the staining of immunoreactive NF-κB p65 in preterm ( 24.2%, 57.6% ) by vaginal dehvery compared to tissues obtained term delivery (6.7%, 13.3%, P ＜0.01 ). Conclusion In this study, the expression of NF-κB p65 did not show significant change in term delivery before and after labor. NF-κB p65 in premature delivery was higher than term delivery, and it had no relationship with the delivery ways.

OBJECTIVE:To improve the level of patent protection of traditional Chinese medicine in China.METHODS:Analysis was made on the reasons for the lag of patent protection of traditional Chinese medicine on the basis of its current situation.RESULTS&CONCLUSION:The current Patent Law in China is unfit for the technical features of traditional Chinese medicine,and therefore hinders the patent protection.It is suggested that special regulations should be made for patent protection of traditional Chinese medicine.

OBJECTIVE:To provide reference for Chinese pharmaceutical manufacturing enterprises to better understand and reasonable utilize the pharmaceutical administrative protection.METHODS:The essence and connotation of pharmaceutical administrative protection were defined by analyzing its origin,development and the regulations;and its role,shortcomings and future development were analyzed.RESULTS & CONCLUSIONS:Pharmaceutical administrative protection is a key part of pharmaceutical intellectual property protection system and plays a very important role in protecting pharmaceutical intellectual property and promoting the development of pharmaceutical industry.Yet it remains to be further improved in view of its shortcomings.

As the repeated emergence of accounting communication distortion and criminal behaviors among accounts,the absence of accounts′ professional ethics is drawing increasing attention from the general public.The professional ethics absence is partially related to the imperfect self-discipline of accountants.However,self-discipline by its own can never solve the absence of accounts′ professional ethics to some extent.Certain social factors are also responsible,which are analyzed in this thesis,aiming to provide a welcoming external environment for the improvement of professional ethics among accountants.

OBJECTIVE:To discuss the routes for research and development of traditional Chinese medicine.METH?ODS:Comparative and multi-phase thinking methods were used to analyze the difference and commonness between tradi?tional Chinese medicine and Western medicine,then the research and development goals and routes of traditional Chinese medicine were established.RESULTS&CONCLUSION:Research and development of tradition Chinese Medicine should be carried forward on the basis of"tradition",that is modern methods combined with traditional theories,or modern methods combined with modern theories.In other words,the same goal can be achieved by different routes.

OBJECTIVE:To make sure who is liable for Adverse Drug Reactions(ADRs)and what kind of legal obligation should they bear and how to bear.METHODS:The concerned laws and regulations were studied by literature research method and comparative study method.RESULTS:The legal obligations involved in ADRs were tort liability and administrative liability.The obligation attribution principles were different.The fault principle should be applied to the unpredicted“develop_ mental danger”of drugs.CONCLUSION:The compensatory and relieving acts related to ADRs damages should be formulated in China.

OBJECTIVE:To provide references for China in the formulation of international marketing strategy of tradi?tional Chinese medicine(TCM).METHODS:Related literatures were referred to and the current international marketing con?cepts of Chinese traditional medicine in China were analyzed.RESULTS&CONCLUSION:The internationalized target market for TCM is indefinite,the international market demand is unknown,the propaganda is without a definite aim,and the language platform for international academic communication is insufficient.It is suggested that the target market for TCM should aimed at general nursing,chronic and stubborn diseases,the efficacy and safety of TCM should be verified by control experiment and cost-effectiveness analysis,the international communication abilities of TCM and its practitioners should be improved so as to facilitate the internalization of TCM.

OBJECTIVE:To study the content and feature of licensed pharmacist qualification examination abroad in order to provide the evidence for the reform of licensed pharmacist qualification examination in China.METHODS:The relevant literature was referred to and a comprehensive analysis was made.RESULTS &CONCLUSION:Strict control over the inclusion criteria in the examination should be strengthened in China.The content and the types of questions should be adjusted to test the real competency of the examinees.The targeting role of the examination should be reinforced,and monitoring as well evaluating system should be established to upgrade the degree of openness.Foreign graduated pharmacological students and pharmacists should be allowed for licensed pharmacist qualification examination in China and registered.The association of licensed pharmacists should play its full potentials.

Objective To design a software for multiplex video-laparoscope image management. Methods The system adopts ACCESS DBMS and uses Visual C++6.0 based on MFC to develop programs on platform of Windows XP. Results The software has the function of playback and manifold images process. Conclusion The user interface is sententious and intuitive, so the system is true of the operation habits of doctors.