Severe acute lung injury (ALI), leading to respiratory failure caused by H1N1 infection, developed in a 34-year-old man during a work-up for non-small cell lung cancer. Although he fully recovered through instant treatment with oseltamivir, mechanical ventilation was required again, 7 days later, due to subsequent diffuse alveolar hemorrhage (DAH). Finally, his condition improved and he was able to move out of the intensive care unit. However, multiple pulmonary metastatic nodules appeared over a period of one month, suggesting the aggressive nature of lung cancer. Although he was discharged after chemotherapy, his prognosis seemed poor, considering the rapidity of growth of the lung cancer. It is important to recognize that DAH can occur after acute lung injury caused by influenza virus.
Acute Lung Injury ; Adult ; Carcinoma, Non-Small-Cell Lung ; Hemorrhage ; Humans ; Influenza, Human ; Intensive Care Units ; Lung Neoplasms ; Orthomyxoviridae ; Oseltamivir ; Prognosis ; Respiration, Artificial ; Respiratory Insufficiency