BAcKGROUND:The specific research on the interaction between feet and ground when jogging,plays an important role for a deeper understanding of the basic laws of human motion.OBJECTIVE:To test dynamic foot pressure distribution during jogging of 64 undergraduates.DESIGN,TIME AND SETTING:A single sample design,the experiment was carried out in Tianjin Normal University Sports Institute in March 2009.PARTICIPANTS:A total of 68 male collego students,without history of foot traumatic or deformities and with normal ankle joint,were involved in this study.METHODS:Totally 68 university students were analyzed by the Footacan USB2 system(RSscan,Belgium)when jogging atnormal gait(5m/s).Dynamic foot pressure was determined three times.Analysis of foot pressure distribution system could gain a complete gait cycle of foot pressure distribution,data acquisition and analysis software used footscan SOFTWARE7.0,foot process of analysis was divided into 10 regions:the first phalange,the second to the fifth phalanges,the first metatarsal,the second metatarsal,the third metatarsal,the fourth metatarsal,the fifth metatarsal,arch,medial heel and lateral heel.MAIN OUTCOME MEASURES:Foot pressure,intensity of pressure,force interval and impulse when jogging.RESULTS:The foot stress-time curve showed a single peak;foot maximum pressure located at the second metatarsal,the site of impulse descending order was the third metatarsal.the first metatarsal,heel,the first phalange,the fourth metatarsal,the fifth metatarsal,the second to the fifth phalange,arch;the distribution of both feet was similar.The pressure of right foot in the second metatarsal,the first metatarsal and the first phalange was significantly greater than the left foot;The contact phases of the full foot and deport from ground occupied 90% of support time,the pressure center was densely in the middle of half sole,the fore intarval of sole was long.The contact time of right foot was significantly larger than left foot.The biggest impulse was the site of the second metatarsal,the order from great to small was the first metatarsal,the third metatarsal,the first phalange,heel,the fourth metatarsal,arch.the second to the fifth phalange,the fifth metatarsal;the distribution of both feet was similar.The impulse of right foot was greater than left foot,while the impulse of the second metatarsal,the first metatarsal and the first phalange were greater than left foot,the difference had statistical significance.CONCLUSI0N:The largest pressure part is the second metatarsal when jogging,the pressure center in the foot locates in the middle of half sole,and the largest impulse is the second metatarsal,most of the impulse focus on the front end of the first to the third metatarsals of the half sole.It is indicated that the middle part of the footpad would be injured easily when jogging,so we should pay attention to the selection of shoes when exercising.

The paper introduces reference work in the new age from its modes, contents, characteristics and developing strategies,including establishing characteristic resources, improving quality of librarians, carrying out network consultant and information navigation, establishing collaborative digital reference, in order to provide reference for primary hospital libraries.

Antiviral Agents ; therapeutic use ; Drug Therapy, Combination ; Drugs, Chinese Herbal ; therapeutic use ; Hepatitis B, Chronic ; drug therapy ; Humans ; Interferon-alpha ; therapeutic use ; Lamivudine ; therapeutic use ; Phytotherapy

Objective To observe the therapeutic effect of treatment of cerebral apoplexy with head acupunc-ture and body acupuncture. Methods 203 cases with cerebral apoplexy were randomly divided into head acupuncture with body acupuncture group(105 cases) and body acupuncture control group(98 cases). Symptom and sign were gra-ded and comprehensive therapeutic effects were assessed. Results There were significant differences of the cure rates and the observed indices between the head acupuncture with body acupuncture group and body acupuncture control group. Conclusion The head acupuncture with body acupuncture can obviously improve the cerebral ischemia and anoxia, and increase limb motor function and ability of daily living in the patients of deep cerebral infarction.

Objective To investigate the reason for embolism in ulnar artery after the injury. Methods 32 cases with repaired ulnar arteries were studied after 3～6 months' countercheck, physical test and ultrasonography (US) were performed to examine the blood flow in ulnar arteries. Results Embolism occurred in 20 repaired arteries of 32 cases. Conclusion Embolism are prone to occur after the injury of ulnar artery.

Objective To probe the relationship on TCM syndromes and related index of metabolic syndrome.Methods 1124 people who receive physical examination were undertaken TCM syndrome differentiation,and five viscera syndromes,the deficiency syndromes,excess syndromes,cold and heat syndromes were found.The relations between TCM syndromes and waist circumference,triglycerides,high-density lipoprotein,blood pressure,fasting blood glucose were studied.Results ①The deficiency syndrome groups and the groups of metabolic syndrome related index by clustering analysis had a higher consistency.②Discriminated analysis demonstrated waist circumference,high-density lipoprotein,and diastolic blood pressure could be used to determine liver syndrome.Blood sugar could be used to determine kidney syndrome.Waist could distinguish blood deficiency syndrome.Blood glucose and systolic blood pressure could distinguish Yin deficiency syndrome.Systolic blood pressure could determine Qi stagnation syndrome.Siastolic blood pressure could determine heat syndrome.The liver syndrome group and the actual liver syndrome group had higher consistency by discriminated analysis.After establishing the discriminated equation,total correct rate of distinguishing were 57.3％,67.1％,63.8％,61.5％,52.4％,47.2％.③Receiver operating characteristic curve analysis showed that blood glucose had diagnostic significance to renal syndrome.The area under the curve was 0.562.Triglycerides,blood glucose,blood pressure had diagnostic significance to Yin deficiency syndrome.The areas under the curve were 0.541,0.556,0.580 and 0.569.Waist circumference,triglycerides,high-density lipoprotein had diagnostic significance to moisture syndrome.The areas under the curve were 0.622,0.609 and 0.605.Diastolic blood pressure had diagnostic significance to heat syndrome.The area under the curve was 0.544.Conclusion By the multifarious analytical methods,we can see that syndromes have more contacts to related index of metabolic syndrome.

Objective To explore the clinical signifcance of changes of serum Ang Ⅱ,hs-CRP and BNP levels and the relationship with atrial fibrillation(AF),and the risk factors of AF recurrence.Methods 100 patients with AF were selected in this study,and they were divided into two groups:paroxysmal atrial fibrillation group (n =54),durative atrial fibrillation group(n =46),and 50 healthy subjects were selected as control.The levels of serum Ang Ⅱ,BNP were detected by radioimmunoassay,and hs-CRP was detected by immunoturbidimetry.Results The levels of Ang Ⅱ,hs-CRP and BNP in atrial fibrillation patients were significantly increased as compared to control group (P ＜ 0.01).The levels of Ang Ⅱ,hs-CRP in the durative atrial fibrillation group were higher than those in the paroxysmal atrial fibrillation group.The levels of serum Ang Ⅱ,hs-CRP were positively correlated with serum BNP level (r =0.563,0.678,all P ＜0.01).The level of serum Ang Ⅱ was positively correlated with serum hs-CRP level(r =0.626,P ＜ 0.01).Multiple logistic regression analysis revealed that hs-CRP and BNP were the important risk factors of atrial fibrillation recurrence[OR value =2.42,95％ CI(1.84 ～ 5.26) ;OR value =2.14,95％ CI(1.37 ～.86)].Conclusion The serum AngⅡ,hs-CRP and BNP may play important roles in the development of AF.hs-CRP and BNP may be the independent risk factors of AF.The detection of hs-CRP and BNP may be related to recurrence prognosis in patients with AF.

Objective To explore the relationships between Serum levels of tumor necrosis factor-alpha TNFα,1L-6,adiponectin and insulin resistance in type 2 diabetes.Methods 80 T2DM patients and 40 healthy controls were recruited.Levels of serum TNF-α,IL-6,adiponectin,plasma glucose,insulin and BMI were measured.Insulin resistance was evaluated by HOMA-IR.Results The levels of TNF-α and IL-6 in T2DM group were significantly higher than that in control group(all P＜0.05);The levels of adiponeetin in T2DM group was significantly lower than that in control group(P＜0.05).The levels of TNF-α and IL-6 were positively correlated with HOMA-IR(P＜0.05),adiponeetin was egatively correlated nwith HOMA-IR(P＜0.01).Conclusion TNF-α,IL-6 and adiponectin were closely related with insulin resistance,and should take parts in development of T2DM.

Thiazolidinedione (TZD) is a powerful insulin sensitizer in the treatment of type 2 diabetes. It acts as a ligand to the nuclear receptor PPARγ (peroxisome proliferator-activated receptor-gamma) and induces transcription of PPARγ responsive genes. TZD controls lipid synthesis and storage in adipose tissue, liver and many other tissues through PPARγ. Derivatives of TZD, such as rosiglitazone (Avandia) and pioglitazone (Actos), are more powerful than metformin or berberine in insulin sensitization. Although they have common side effects such as weight gain and edema, these did not influence the side effects in general. However, recent findings of risk for congestive heart failure and bladder cancer have indeed significantly impaired their future in many countries. European countries have prohibited those drugs and in 2011, US will terminate application of rosiglitazone in clinics and hospitals. The multiple country actions may mark the end of TZD era. As a result, there is a strong demand for identification of TZD substitute in the treatment of type 2 diabetes. In this regard, literature about PPARγ ligands and potential TZD substitute are reviewed in this article. Histone deacetylase (HDAC) inhibitor is emphasized as a new class of insulin sensitizer here. Regulators of SIRT1, CREB, NO, p38, ERK and Cdk5 are discussed in the activation of PPARγ.

Objective To evaluate the clinical effects of pulsatile perfusion on the renal inadequacy during cardiopulmonary bypass ( CPB). Methods From January 2007 to May 2010, 55 patients with renal inadequacy undergoing open heart surgery were randomized into pulsatile group ( n = 28 ) and nonpulsatile group (n =27). Following parameters were examined: urea nitrogen , creatinine,uric acid, urine volume and blood gas, electrolyte and lactic acid before arteriae aorta opening. Results The urine volume during CPB was significant higher in the pulsatile group ( P ＜0. 01). The blood lactate level before arteriae aorta opening were significant lower in the pulsatile group ( P ＜0. 01). Conclusion The pulsatile flow is better than nopulsatile flow in oxygen metabolism of renal protection.