1.Statistical analysis of scientific papers published by postgraduate in Beijing Neurosurgical Institute from 2001 to 2010
Rui LI ; Xiaoyan CHENG ; Yazhuo ZHANG
Chinese Journal of Medical Education Research 2012;11(1):21-24
ObjectiveThe aim of this paper is to investigate more effective ways in postgraduate academic training and research management by analysis of the scientific papers published in graduate school period.MethodsThe categories,quantity and quality of the scientific papers published by postgraduate students in Beijing Neurosurgical Institute from 2001 to 2010 were analyzed statistically.ResultsThe quantity of papers published by postgraduate students has been stably improved year by year,and the quality of the papers has shown an obvious tendency of increasing.ConclusionsAn outstanding research capability of the whole institute,the strict demand of supervisors and the reasonable encouraging systems in scientific research management are all the guarantee of the improvement of academic research ability of postgraduate students in Beijing Neurosurgical Institute.
2.Investigation and analysis of job burnout level of nurses with different education degrees
Min ZHANG ; Xiuhong LI ; Yazhuo XUE
Chinese Journal of Practical Nursing 2013;29(30):43-45
Objective To understand the job burnout conditions of nurses with different education levels in Ningyang county,analyze the influence of education level on job burnout,in order to find strategies to relieve the job burnout,reduce burnout,increase working enthusiasm,then further lower nurse turnover rate and stabilize of the nurse team.Methods A total of 150 nurses in the first hospital of Ningyang county participated in the investigation using Maslach Burnout Inventory (MBI) in December 2012.The survey data underwent statistical analysis.Results The results show that in the dimension of emotional exhaustion,education level showed main effect.While in the dimension of depersonalization and personal accomplishment,the education level showed no main effect.Conclusions Education levels have a significant impact on job burnout of nurses,mainly in the emotional exhaustion dimension.Hospital managers should pay attention to job burnout of nurses with college degree,reduce their occupational burnout through positive changes in personal and organizational factors.
3.Study on social discrimination and its influencing factors of patients with menial disorders
Xiuhong LI ; Qiuju TIAN ; Yazhuo XUE
Chinese Journal of Behavioral Medicine and Brain Science 2014;23(7):655-657
Objective To describe the public discrimination against patients with mental disorders,and to explore its influencing factors.Methods This study was a descriptive study.A total of 1 378 public received the survey.The survey instruments include general information questionnaire and assessment scale of discrimination against patients with mental disorders.Results The scores of the scale of discrimination against patients with mental disorders was (2.07± 0.61).The score of risk dimension was higher(2.17±0.87),and the ability dimension was lower(1.65±0.64).Multiple regression analysis showed that factors influencing the total score of the scale were type of investigation objects,age,gender,educational background,contact degree and life connection degree to the patients with mental disorders.Conclusion Because psychiatric patients had perceived stigma,and social demographic factors,clinical factors,social and psychological factors could influence their perceived stigma,so the nurse should pay more attention to discrimination against patients,and reduce or eliminate the discrimination toward the patients,then promote recovery of the patients.
4.Relationship of the old people with hypertension and metabolic syndrome
Li LIU ; Ruoyu WANG ; Yazhuo LIU ; Xiaojie SUN
Chinese Journal of Primary Medicine and Pharmacy 2015;22(1):32-35
Objective To analyze the morbidity of the old people with hypertension and metabolic syndrome (MS),the characteristics of MS components distribution,and correlation hypertension and MS.Methods 438 old patients over 60 with hypertension were selected randomly from cheek-up crowd in the physical examination center of Affiliated Zhongshan Hospital of Dalian University in 2013.Abdominal girth,height,body mass were measured,and then calculated BMI.The indicators such as FPG,TC,TG,HDL-C,LDL-C were detected and analyzed.Results The total morbidity of MS in the old people with hypertension was 37.7%,39.0% from male people,36.7% from female people,and there was no difference between genders(x2 =0.46,P > 0.05).The level of BMI,abdominal girth,FPG,and TG in the old people with MS were higher than the people without MS(t =4.83,8.53,5.08,7.29,all P <0.05),and HDL-C was lower than the people without MS(t =-9.67,P < 0.05).The level of FPG in women was higher than that in men apparently(x2 =5.82,P < 0.05),and the level of HDL-C was lower than that in men apparently (x2 =8.73,P < 0.01).The risk factors to MS include BMI,abdominal girth,FPG,TG (OR =2.139,1.106,2.156,2.315,all P <0.05),and HDL-C is protective factor to MS(OR =0.039,P <0.05).Conclusion Hypertension might increase MS morbidity of old patients.Hypertension related with MS closely.The risk factors include BMI,abdominal girth,FPG,TG,on the other hand HDL-C is protective factor to MS.
5.Investigative study on awareness rate of mental health knowledge in Tai'an city community
Xiuhong LI ; Xueqin ZHANG ; Hui ZHANG ; Yazhuo XUE
Chinese Journal of Behavioral Medicine and Brain Science 2015;24(1):78-79
Objective To know the status of mental health knowledge in Tai'an city community,and thus to provide the basis for the popularization of community about mental health knowledge.Methods A self-designed mental health knowledge questionnaire was used to survey 151 cases of community residents.Results The community mental health knowledge score was (6.73±2.72),and lower than the average.The mental health knowledge score had significant difference between male (6.26±2.50)and female (7.15±2.85) (t=-2.026,P<0.05).The mental health knowledge score also showed significant difference in community residents with different age,culture degree and occupation (P< 0.05).Conclusion The community residents in Tai'an city generally lack of mental health knowledge.The relevant departments should actively take effective measures to popularize the mental health knowledge in different groups so as to enhance public awareness of mental health knowledge and thus to do better in prevention and control of mental disorders.
6.Research and Development of A Kinect Based Virtual System for Upper Limb Rehabilitation.
Weili DING ; Yazhuo ZHENG ; Yuping SU ; Xiaoli LI ; Xiuli WEI
Journal of Biomedical Engineering 2015;32(3):563-568
We developed a rehabilitation system by using the virtual reality technique and the Kinect in this paper. The system combines rehabilitation training with HMI and serious game organically, and provides a game and motion database to meet different patients' demands. Extended interface of game database is provided in two ways: personalized games can be developed by Virtools and Flash games which are suitable for patients' rehabilitation can be download from the Internet directly. In addition, the system provides patients with flexible interaction and easy control mode, and also presents real time data recording. An objective and subjective evaluation method is proposed to review the effectiveness of the rehabilitation training. According to the results of short questionnaires and the evaluation results of patients' rehabilitation training, the system compared with traditional rehabilitation can record and analyze the training data, which is useful to make rehabilitation plans. More entertainment and lower cost will increase patients' motivation, which helps to increase the rehabilitation effectiveness.
Computer Simulation
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Humans
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Internet
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Rehabilitation
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instrumentation
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methods
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Upper Extremity
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physiopathology
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User-Computer Interface
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Video Games
7.Correlation Between Shear Wave Elasticity and Collagen Fiber in Breast Disease
Zhili WANG ; Lu SUN ; Yazhuo HU ; Ye LI
Chinese Journal of Medical Imaging 2014;(10):721-724
Purpose To study the differences of shear wave elasticity and the content of collagen fiber between benign breast lesions and malignant breast lesions, and to analyze the correlation between shear wave elasticity and the content of collagen fiber. Materials and Methods 106 patients with 116 breast lesions who were referred to PLA General Hospital for ultrasound-guided biopsy or surgery underwent shear wave elasticity examination, the biopsy specimen underwent Van Gieson (VG) dye and Image-Pro Plus 5.1 software was used to quantitatively analyze the content of collagen fiber. Results Malignant lesions exhibited signiifcantly higher max elasticity, mean elasticity, and elasticity ratio between lesions and surrounding parenchyma (140.43±70.16) kPa, (63.11±33.68) kPa, 3.49±1.95 than benign lesions (54.64±48.53) kPa, (34.52±25.23) kPa, 2.25±1.48 (t=5.329, 4.382 and 4.487, P<0.01). The content of collagen fiber of malignant lesions was signiifcantly higher than that of benign lesions (t=8.437, P<0.01). There was a positive correlation between max elasticity and the content of ifber collagen (r=0.746, P<0.05). Conclusion The elasticity of breast lesions has a close correlation with the content of collagen ifber, and collagen ifber might play an important role in the development of breast carcinoma.
8.Correlation between grey scale ultrasonographic feature and estrogen receptor, progesterone receptor and human epidermal growth factor receptor-2 expression in infiltrating ductal cancer of breast
Min CHEN ; Junlai LI ; Danfei SONG ; Yan ZHANG ; Yazhuo LI ; Lixin WEI
Chinese Journal of Ultrasonography 2008;17(4):333-335
Objective To evaluate the relationship between the grey scale ultrasonographic feature and estrogen receptor(ER),progesterone receptor(PR)or human epidermal growth factor receptor-2(HER-2)expression in infiltrating ductal cancer(IDC)of breast.Methods Seventy-three patients with IDC confirmed pathologically were involved in this study.The specimens wete examined immunohistochemistically to judge the expression of the related factors.ER,PR and HER-2 expression of the mastectomy specimens were determined with immunohistochemical staining technique.The correlation between the ultrasonographic features and ER,PR or HER-2 positive expression was analyzed. Results The ER positive rate in lesions with the spicule sign,echogenic halo or posterior shadowing were higher than in lesions without the spicule sign,echogenic halo or posterior shadowing(P<0.01).The HER-2 positive rate in lesion with the calcifications and lymphadenectasis in axillary was higher than that in lesions without calcifications,or lymphadenectasis in axillary(P<0.05).Conclusions A certain correlation exists between the ultrasonographic features and ER,HER-2 expression in patients with IDC.
9.Endoscopic Treatment of an Adult with Tegmental Astrocytoma Accompanied by Cerebrospinal Fluid Dissemination.
Runchun LU ; Chuzhong LI ; Xinsheng WANG ; Yazhuo ZHANG
Journal of Korean Neurosurgical Society 2017;60(3):375-379
Midbrain gliomas are relatively rare neoplasms with a generally benign prognosis, with dissemination or metastasis not previously reported. We describe here a woman, in whom magnetic resonance imaging scans showed hydrocephalus and a tegmental lesion in the upper aqueduct. Endoscopic third ventriculostomy and biopsy were performed; during surgery, a second small lesion was observed in the infundibular recess. Histologically, the two lesions had the characteristics of low grade astrocytoma, suggesting that the midbrain astrocytoma may have been disseminated via the cerebral spinal fluid to the infundibular recess. Postoperatively this patient received radiotherapy for nearly one month. Although patients with these tumors are not usually administered adjunctive therapy, radiation and, combined modality therapy, including surgery, radiotherapy, and chemotherapy, may be beneficial in patients with midbrain gliomas with dissemination.
Adult*
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Astrocytoma*
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Biopsy
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Cerebrospinal Fluid*
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Combined Modality Therapy
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Drug Therapy
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Female
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Glioma
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Humans
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Hydrocephalus
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Magnetic Resonance Imaging
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Mesencephalon
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Neoplasm Metastasis
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Neuroendoscopes
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Prognosis
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Radiotherapy
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Ventriculostomy
10.Effect of naloxone on neural functional recovery of rats with traumatic brain injury
Yanhui SUN ; He MENG ; Yazhuo ZHANG ; Qingguo LI ; Meizhen SUN ; Hongyun WANG ; Yue HE
Chinese Journal of Tissue Engineering Research 2005;9(37):162-163
BACKGROUND: As unspecific antagonist of opiate receptor, naloxone is widely used for multiple diseases which are related with abnormal release of endogenous opium. At present, researches suggest that large dosage of naloxone is used at early period can decrease death rate of patients with acute craniocerebral injury and promote neural functional recovery.OBJECTIVE: To investigate the effect of naloxone on improving the nervous function of rats with acute craniocerebral injury and to analyze effectively.DESIGN: Randomized grouping design based on the experimental animal.SETTING: Beijing Neurosurgical Institute.MATERIALS: Totally 250 SD rats were divided randomly into 0.3, 1.0,3.0, 9.0 mg/kg naloxone group, positive control group and negative control group.METHODS: Craniocerebral injured model was established with Feenly free fall struck, and the medicine was given 30 minutes after injury. The rats of the first four experimental group were injected transpeniponeally with naloxone hydrochloride by 0.3 mg/kg, 1.0 mg/kg, 3.0 mg/kg and 9.0 mg/kg respectively once a day; meanwhile, the control groups were given 2 mg citicoline sodium for injection and 0.5 mL normal saline per rat respectively. The longest time was 14 days.MAIN OUTCOME MEASURES: MNSS neural functional score was used every day. The brain edemas of 8 rats in each group were measured with wet-dry weight methods on the second and the fourth day after head trauma.RESULTS: Among 250 rats, 172 entered the final analysis. The nervous function of rats in naloxone groups was better than the two control groups (P < 0.01), and that in 1, 3 and 9 mg/kg naloxone group were better than 0.3 mg/kg group (P < 0.05), but there were no significant differences a mong the three naloxone groups (P > 0.05). The brain edemas of rats in naloxone groups were lighter than that in the control groups (P < 0.05), and that of 1, 3 and 9 mg/kg groups were lighter than 0.3 mg/kg (P < 0.05), but there were no significant differences among these three groups (P > 0.05).CONCLUSION: Naloxone can decrease the brain edemas of rats with traumatic brain injury, promote the nervous function recovery, and the treatment effect changes with the dosage during some range.Therefore, the experiment illustrates that naloxone can decrease the brain edemas of experimental brain injury in SD rats and improve the nervous function, but the effect of naloxone is associated with the dosages in some range.