1.Diagnostic value of multi-slice spiral CT for emergency traumatic liver and spleen rupture
Shengjun DU ; Yanning LIU ; Yazhou GAO ; Zheng XIAO ; Junkai DU
Journal of Xi'an Jiaotong University(Medical Sciences) 2015;(6):854-856,861
Objective To evaluate the diagnostic value of multi-slice spiral CT (MSCT)for traumatic spleen and liver rupture.Methods We made a retrospective analysis of 140 cases of liver and spleen injury with clinical manifestations confirmed by operation.MSCT examination results and clinical data were compared.Results Of the 140 cases,male patients outnumbered female ones,and the peak age was 10 - 30 years old.The injuries were most commonly attributed to traffic accident and falling.There were 69 (49%)cases of spleen injury,5 1 (36%) cases of liver injury,and 20 (14%)cases of both.Liver and spleen injuries showed on MSCT examination were liver and spleen laceration, hematoma within the liver and spleen as well as hematoma beneath the envelop. Conclusion MSCT has an important diagnostic value for traumatic liver and spleen rupture and thus can guide clinical treatment choice.
2.Application progress of artificial intelligence in the screening and identification of drug targets
Chao WANG ; Fu XIAO ; Miaozhu LI ; Ying PAN ; Xiao DING ; Feng REN ; Alex ZHAVORONKOV ; Yazhou WANG
Journal of China Pharmaceutical University 2023;54(3):269-281
In recent years, artificial intelligence (AI) has developed rapidly, with improved computing power and algorithms, which has greatly facilitated the collection and processing of biological, chemical information and clinical data, injecting new vitality into the research and development of new drugs.In this review, we began with a brief overview of the development and the main algorithms of AI in drug discovery.Then we elaborated through several specific cases on the various scenarios of AI application, including target identification, protein structure prediction, hit generation and optimization etc.Finally, we focused on a recent example to discuss the high efficiency of "end-to-end" application of AI.
3.Development of health service in Hunan Province.
Min HU ; Gong GUO ; Xiaohua ZHAO ; Zhenqiu SUN ; Hai GUO ; Min GAO ; Dan XU ; Yazhou XIAO ; Fang ZENG ; Youzhe ZENG
Journal of Central South University(Medical Sciences) 2011;36(7):692-696
OBJECTIVE:
To study the health service development in Hunan Province, and to find out the advantages and disadvantages, and to make tentative specific suggestions.
METHODS:
Comparison was made in Yunnan, Hunan, and Zhejiang Provinces in 4 major areas: health institutions, personnels, facilities, and funding.
RESULTS:
The overall health service of Hunan Province was good: The health resources increased, the allocations were reasonable, and the health expenditure decreased. Some problems appeared, such as backward primary health, shortage of medical talents, inefficient use of hospital beds, deducted government investment, increased business income, and large urban-rural gap.
CONCLUSION
There is urgent need to further develop health institutions and increase personnels, particularly improving the primary health care and making use of traditional Chinese medicine; improving the management of hospital beds to increase efficiency, increasing financial support to reduce the patients' burden, and ensuring the need of rural health care.
China
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Delivery of Health Care
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trends
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Health Services
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economics
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statistics & numerical data
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Health Services Administration
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Humans
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Rural Health
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economics
4.A comprehensive evaluation of the health services in Hunan Province.
Gong GUO ; Qiong HE ; Zhenqiu SUN ; Yi BAI ; Linyong XU ; Min HU ; Yazhou XIAO ; Xiaohua ZHAO ; Fang ZENG ; Youzhe ZENG
Journal of Central South University(Medical Sciences) 2012;37(5):532-536
OBJECTIVE:
To establish a comprehensive evaluation system for the development of health services, and to assess the levels of health services in 2008 and 2009 in Hunan compared with seven other provinces in central China, so as to provide a basis for hygiene management decisions.
METHODS:
In order to establish a comprehensive evaluation system, a Delphi method, a boundary value method, and an RSR method were applied, respectively, to survey indices of health service development, to screen indices, and to determine index weights. A weighted TOPSIS method was used to evaluate the development status of health services of the eight provinces.
RESULTS:
The Cronbach's alpha coefficient of the questionnaire was 0.884, indicating a proper surface validity and a content validity. The expert positive coefficient, authority coefficient and Kendall coefficient were 93.75%, 0.8117, and 0.31, respectively. A comprehensive evaluation system, which consisted of 3 primary indices, 10 secondary indices and 52 tertiary indices, was established. The result of the comprehensive evaluation showed that the health services development of Hunan Province ranked 7th and 6th among the 8 central provinces for 2008 and 2009, respectively.
CONCLUSION
The established, comprehensive evaluation system has a high reliability. Health services development of Hunan Province is relatively backward among the 8 central provinces.
China
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Health Services
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standards
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statistics & numerical data
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Humans
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Surveys and Questionnaires