Objectives To explore the clinical features, diagnosis and treatment of Crohn’s disease complicated by erythromelalgia (EM) in a pediatric case. Methods The clinical manifestation, results of laboratory testing and endoscopy, mutational analysis of the SCN9A gene, and the follow-up record were collected and analyzed based on review of literature to a thirteen-year-old girl with Crohn’s disease complicated by erythromelalgia. Results The patient experienced symptoms of anorexia, fatigue, diarrhea, dark red and swelling skin, increased skin temperature and burning pain in her both lower extremities during the course of disease. The endoscopic ifndings included multiple ulcerations and polypoid protrusion lesion in colon, and the pathological examination showed the local abscess formation in colonic mucosa. The mutation in SCN9A gene of the child was excluded by gene analysis. The symptoms were gradually ameliorated after treatment using prednisone and mesalazine combined with dipyridamole and low-molecular-weight heparin calcium. Conclusions Crohn’s disease complicated by erythromelalgia is rare. The pathogenesis may relate to immune factors, thrombocytosis, and hyper-coagulable states, etc. The combination of glucocorticoids, 5-aminosalicylic acid and anticoagulants may lead to a better therapeutic effect.

Objective To establish the index system of core competencies for midwife. Methods By qualitative research, semi-structured interview were carried out in 17 staffs relevant to midwifery. Results “Antenatal care”,“Intrapartum care”,“Postnatal care”, “Feminine care”, “Public health care &Integrative competency”, and “Professional quality” were established as 7 main midwifery core competency frame. Conclusions This research explores the core competency for midwife from various perspectives, and we construct the frame of index system according to national conditions. The achievement of core competencies for midwife requires policy, law and manpower resource as guarantee.