1.EFFECT OF THE DIFFERENCE OF AEROBIC CAPACITY ON ENERGY CONTRIBUTION RATE IN WINGATE TEST
KENICHI MORI ; TOSHITSUGU YOSHIOKA ; KOUSUKE SHIRAMATSU ; YASUSHI KARIYAMA ; MITSUGI OGATA
Japanese Journal of Physical Fitness and Sports Medicine 2011;60(5):503-510
The purpose of this study was to investigate the influence of physiological factors which effect oxygen kinetics and energy system contribution on the power of Wingate test (WT), with focusing on the difference of aerobic capacity. Twenty three male track and field athletes (sprinters, long distance runners and decathletes) performed the WT on electromagnetic-braked cycle ergometer. The applied resistance was 7.5% of body weight, and the duration was 60 seconds. Moreover, aerobic capacity (maximal oxygen uptake [VO2max]) was determined by an incremental test, and anaerobic capacity (maximal accumulated oxygen deficit [MAOD]) was determined by a supramaximal constant load test. The oxygen uptake during each test was recorded by a breath-by-breath method. The participants were divided into two group which was high VO2max group (High group; n = 11) and low VO2max group (Low group; n = 12). In the results, although the VO2max was significantly higher in the High group, the MAOD was not significantly different between two groups. The oxygen uptake during WT was significantly higher in the High group, and the accumulated oxygen deficit during WT was significantly higher in the Low group. The aerobic contribution was significantly higher in the High group than in the Low group. In contrast, the anaerobic contribution was significantly higher in the Low group than in the High group. These results suggest that by the difference of aerobic capacity, aerobic and anaerobic energy supply contribution was different in WT.
2.Efficacy of palliative radiation for advanced gastric cancer patients
Shuji Hiramoto ; Ayako Kikuchi ; Akira Yoshioka ; Yuka Otsu ; Yasushi Kohigashi ; Yoko Goto ; Yurie Tsutsumi ; Masahiro Hiraoka ; Koji Ono
Palliative Care Research 2015;10(2):514-517
We have several choices against bleeding and obstruction in advanced gastric cancer patients such as surgical or endoscopic therapy. But we have few reports about palliative radiation. We conduct this study that we perform palliative radiation for unresectable advanced gastric cancer patients between April 2006 and March 2014 in single center. In the aim of the therapy, to stop gastric bleeding were 8, and to improve obstruction depend on gastric cancer were 4. Response rate of stop bleeding was 63%, and improve obstruction was 50%. Median duration of stop bleeding was 103 day, and improve obstruction was 52 day. Overall survival time was 567 day, survival time after the start of radiotherapy was 105days. Radiotherapy was limited in cases because onset time of response needed in comparison with surgical or endoscopic therapy. However, given minimally invasive therapy and a certain response, we can choice it so much more.
4.The Effects of Stamping or Printing on Tablet or Capsule Readability
Risa KATSUBE ; Yohei MANABE ; Yasushi YOSHIOKA ; Yoichi KAWASAKI ; Masatoshi OKAZAKI ; Yoshihisa KITAMURA ; Toshiaki SENDO
Japanese Journal of Drug Informatics 2018;20(2):81-89
Background: With the marked changes occurring in the medical field, such as rapid population aging, the frequency of one‐dose package use by medication‐dispensing services is increasing. Pharmaceutical companies promote the development of pharmaceutical products that can be identified based on their color, size, and imprinted information to reduce one‐dose packaging errors and difficulties in tablet identification. However, there have not been any studies about the effectiveness of such measures for aiding the identification of tablets in the clinical setting. Therefore, we examined the effects of imprinting on the ease of identification of tablets and capsules.Methods: The study was conducted over a 3‐month period and involved 39 pharmacists aged under 40. The times they needed to transcribe the characters imprinted on each tablet/capsule were measured.Results: The time needed to identify a tablet was significantly shortened by kana printing (p<0.01), whereas more time was required to identify a capsule when the text color was similar to that of the capsule. The observed transcription errors included ‘inaccurately transcribing alphanumeric characters' and ‘omitting units or other information.'Discussion: These results suggest that kana printing is effective at increasing the ease of tablet/capsule identification, which is also affected by the color of the printed text.