1.Nodular Fasciitis in the Buccal Mucosa
Tetsuro Ikebe ; Yuichi Ogata ; Yasuo Takamune ; Kazutoshi Ota ; Takehisa Obayashi ; Masanori Shinohara
Oral Science International 2004;1(2):89-92
A case of nodular fasciitis which arose from the buccal submucosal region is reported. One week after an incisional biopsy, the lesion enlarged alarmingly and protruded from the submucosa. Although a sarcoma was suspected because of rapid growth, the diagnosis of the biopsy was nodular fasciitis showing a haphazard arrangement of plump fibroblasts without atypical mitoses. After complete resection, no signs of recurrence were seen.
2.Clinical features of catheter-related candidemia at disease onset.
Yusuke YOSHINO ; Yoshitaka WAKABAYASHI ; Satoshi SUZUKI ; Kazunori SEO ; Ichiro KOGA ; Takatoshi KITAZAWA ; Shu OKUGAWA ; Yasuo OTA
Singapore medical journal 2014;55(11):579-582
INTRODUCTIONEarly detection of catheter-related candidemia is necessary to ensure that patients receive prompt and appropriate treatment. The aim of the present case-control study is to investigate the clinical features of catheter-related candidemia at disease onset, so as to determine the clinical indications for empiric antifungal therapy.
METHODSAll 41 cases of catheter-related candidemia from September 2009 to August 2011 at a teaching hospital were included in the present study. To determine the characteristics that were risk factors for developing catheter-related candidemia, we compared all cases of catheter-related candidemia with all 107 cases of catheter-related blood stream infection (CRBSI) caused by non-Candida spp.
RESULTSIn comparison with CRBSI due to non-Candida spp., the duration of catheter use was significantly longer in cases of catheter-related candidemia (13.9 ± 9.0 days vs. 23.2 ± 25.2 days). There was also a significant difference in the frequency of pre-antibiotic treatment between catheter-related candidemia and CRBSI due to non-Candida spp. (97.6% [40/41 cases] vs. 44.9% [48/107 cases]). Patients with catheter-related candidemia also had significantly more severe clinical statuses (measured using the Sepsis-related Organ Failure Assessment score) than patients with CRBSI due to non-Candida spp. (7.63 ± 3.65 vs. 5.92 ± 2.81).
CONCLUSIONWhen compared to patients with CRBSI caused by non-Candida spp., patients with catheter-related candidemia had significantly more severe clinical backgrounds, longer duration of catheter use and more frequent prior administration of antibiotic agents.
Aged ; Aged, 80 and over ; Candida ; pathogenicity ; Candidemia ; diagnosis ; Case-Control Studies ; Catheter-Related Infections ; diagnosis ; Female ; Humans ; Male ; Middle Aged