1.Physiological Changes by Half-body Bathing
Ritsuko YAMAZAKI ; Yasuki HONDA ; Ushio HARADA ; Yuji SUZUKI ; Yoshinori OHTSUKA
The Journal of The Japanese Society of Balneology, Climatology and Physical Medicine 2007;70(3):165-171
Purpose
Half body bathing is popular among young women as well as elderly people. As a matter of fact, it is reported that half body bathing has a smaller burden than whole-body bathing from the point of physical influence. To clarify the relation between bathing habitude and health maintenance, that is, as an approach to general understanding the physiological effects by repeating bathing stimuli, the physiological changes by continuing half body bathing were studied.
Methods
Half body bathing was repeated for 4 weeks in healthy female subjects (N=10, age: 30.1±4.8, height: 160.4±6.1cm, weight: 55.6±7.0kg, body mass index: 20.9±1.6kg/m2, mean±SD).
Bathing was performed for 30 minutes and 3times a week, with a level of epigastrium without immersing arms. Changes of blood flow and energy expenditure were measured during bathing at 0W and 4W.
Results and Discussion
By continuing bathing, blood flow increased more rapidly and higher during bathing, in addition, resting energy expenditure increased by 200kcal/day with a significant difference.
From these findings, it is assumed that repeated half-body bathing enhances the increase of blood flow through repeating thermal stimuli, which leads to elevated basal metabolism.
2.Soluble extract of soybean fermented with Aspergillus oryzae GB107 inhibits fat accumulation in cultured 3T3-L1 adipocytes.
Kyoung Ha SO ; Yasuki SUZUKI ; Shinichi YONEKURA ; Yutaka SUZUKI ; Chan Ho LEE ; Sung Woo KIM ; Kazuo KATOH ; Sang Gun ROH
Nutrition Research and Practice 2015;9(4):439-444
BACKGROUND/OBJECTIVES: This study was conducted to investigate the effects of fermented soybean (FS) extract on adipocyte differentiation and fat accumulation using cultured 3T3-L1 adipocytes. MATERIALS/METHODS: 3T3-L1 adipocytes were treated with FS and nonfermented soybean (NFS) extract during differentiation for 10 days in vitro. Oil red O staining was performed and glycerol-3-phosphate dehydrogenase (GPDH) activity was measured for analysis of fat accumulation. Expressions of adipogenic genes were measured. RESULTS: Soluble extract of soybean fermented with Aspergillus oryzae GB107 contained higher levels of low-molecular-weight protein than conventional soybean protein did. FS extract (50 microg/ml) inhibited adipocyte differentiation and fat accumulation during differentiation of 3T3-L1 preadipocytes for 10 days in vitro. Significantly lower GPDH activity was observed in differentiated adipocytes treated with the FS extract than those treated with NFS extract. Treatment with FS extract resulted in decreased expression levels of leptin, adiponectin, and adipogenin genes, which are associated with adipogenesis. CONCLUSIONS: This report is the first to demonstrate that the water-soluble extract from FS inhibits fat accumulation and lipid storage in 3T3-L1 adipocytes. Thus, the soybean extract fermented with A. oryzae GB107 could be used to control lipid accumulation in adipocytes.
Adipocytes*
;
Adipogenesis
;
Adiponectin
;
Aspergillus oryzae*
;
Glycerolphosphate Dehydrogenase
;
Leptin
;
Oryza
;
Soybeans*