1.Recombinant tissue plasminogen activator (r-TPA) in fibrin dissolution due to postoperative endophthalmitis.
Yasmin RIAZ ; Jodhbir S MEHTA ; Arosho FERNANDO ; Veronica FERGUSON
Annals of the Academy of Medicine, Singapore 2006;35(10):723-725
INTRODUCTIONThe aim of this paper was to describe the use of r-TPA for fibrin clot dissolution following endophthalmitis.
CLINICAL PICTUREA 74-year-old man presented with painful loss of vision following routine uncomplicated cataract surgery.
TREATMENTHe underwent standard treatment for postoperative endophthalmitis but despite this, developed a dense fibrin clot. He underwent further intracameral injection of r-TPA.
OUTCOMEFollowing the injection, he had complete clot dissolution within 2 hours without any complications.
CONCLUSIONR-TPA may be used effectively in the treatment of fibrin clots secondary to endophthalmitis following cataract surgery.
Aged ; Cataract Extraction ; adverse effects ; Endophthalmitis ; drug therapy ; etiology ; Fibrin ; drug effects ; Fibrinolytic Agents ; therapeutic use ; Humans ; Male ; Postoperative Period ; Recombinant Proteins ; therapeutic use ; Tissue Plasminogen Activator ; therapeutic use
Result Analysis
Print
Save
E-mail