1.Effects of health education under the concept of health quotient on self-management ability and medication compliance among ulcerative colitis patients
Yashuo FAN ; Huabo LIAO ; Mingjie SUN ; Shuangxi ZHANG
Chinese Journal of Modern Nursing 2019;25(13):1659-1662
Objective? To explore the effects of health education under the concept of health quotient on self-management ability and medication compliance among ulcerative colitis patients. Methods? From December 2015 to December 2017, we selected 140 ulcerative colitis patients at Nanyang City Center Hospital of the Affiliated Hospital of Zhengzhou University as subjects by convenience sampling. All of the patients were divided into observation group and control group with the method of random number table, 70 cases in each group. Control group adopted routine health education, while observation group carried out health education under the concept of health quotient which implemented health education using five dimensions of health quotient concept as start points. The intervention effects of patients of two groups, self-management ability and medication compliance, were compared with the Adult Health Self-Management Skill Rating Scale (AHSMSRS) and Morisky Medication Adherence Scale before (on admission) and after (reexamining three months after discharge) intervention. Results? Before intervention, there were no statistical differences in the dimension scores of AHSMSRS of patients between two groups (P> 0.05). After intervention, the scores of AHSMSRS both groups all increased compared with those before intervention;the scores of diet management, sport management, responses to the diseases, resource usage, self-efficacy and environment self-management and the total score of AHSMSRS in observation group after intervention were higher than those in control group with statistical differences (P<0.05). After intervention, the fine rate of medication compliance of observation group was 95.71% statistically higher than that (85.71%) of control group (P<0.05). Conclusions? Health education under the concept of health quotient can improve self-management ability and medication compliance among ulcerative colitis patients which is worthy of being spread in clinical application.
2.Application of health education using new media in nursing outside the hospital among colon cancer patients
Yashuo FAN ; Huabo LIAO ; Mingjie SUN ; Shuangxi ZHANG
Chinese Journal of Modern Nursing 2020;26(6):779-784
Objective:To explore the effects of health education using new media in nursing outside the hospital among colon cancer patients.Methods:From January 2016 to December 2018, this study selected 86 colon cancer patients at Nanyang Central Hospital as subjects by convenience sampling. A total of 43 patients between January 2016 to June 2017 were in control group, and 43 patients from July 2017 to December 2018 were in observation group. Control group carried out health education outside the hospital, while observation group implemented health education using new media outside the hospital for six months. The effects were compared with the knowledge need questionnaire for cancer patients, Champion Health Belief Model Scale (CHBMS) and the Strategies Used by People to Promote Health (SUPPH) .Results:Six months after discharge, the scores of knowledge need questionnaire of patients in observation group and control group were (41.24±7.64) and (51.94±9.62) respectively ( t=5.712, P<0.01) ; the score of CHBMS of patients in observation group and control group were (118.10±31.53) and (92.20±28.23) respectively ( t=4.013, P<0.01) ; and the score of SUPPH of patients in observation group and control group were (98.37±17.17) and (80.45±17.45) respectively ( t=4.800, P<0.01) ; the differences were all statistical. Conclusions:The application of health education using new media in nursing outside the hospital among colon cancer patients can improve patients' health knowledge need, rebuild the health belief and increase self-management efficacy.
3.Genome-wide identification and effect of MdPEPC family genes during axillary bud outgrowth in apple (Malus domestica Borkh.).
Jiuyang LI ; Congjian SHI ; Yashuo SUN ; Caizhen GAO ; Yaohui ZHANG ; Ming TAN ; Bowen LIANG
Chinese Journal of Biotechnology 2022;38(10):3728-3739
The PEPC family proteins are ubiquitous in various plants and play an important role in the process of photosynthetic carbon assimilation and have many non-photosynthetic biological functions. However, PEPC genes have not been reported in apple. In this study, the members of apple MdPEPC family were identified based on the new apple genome data by bioinformatics analysis, and their expression patterns in different tissues and the apple axillary bud transcriptome treated by decapitation and TDZ (cytokinin) were analyzed in order to explore the role of MdPEPC genes in apple axillary bud outgrowth. The results showed that 6 MdPEPC family members were identified in apple, which distributed on 6 different chromosomes, and had similar physicochemical characteristics. Phylogenetic tree and sequence alignment analysis showed that the MdPEPC could be divided into two subgroups (Group Ⅰ and Group Ⅱ), in which four members in MdPEPC family were clustered into Group Ⅰ, belonging to plant-type PEPCs. However, MdPEPC4 and MdPEPC5 were clustered into Group Ⅱ with AtPPC4, belonging to bacterial-type PEPCs. There were 7 pairs of fragments repeats among MdPEPC members, but no tandem repeats existed. The promoter cis-acting element analysis showed that MdPEPC genes were not only affected by light and stress, but also regulated by multiple hormones. The expression profiles showed that all MdPEPCs except MdPEPC4 and MdPEPC5 were expressed in different apple tissues. Transcriptome data analysis showed that the expression levels of MdPEPC1 and MdPEPC3 were up-regulated after decapitation and TDZ treatment, whereas MdPEPC2 was significantly down-regulated at 48 h after treatments. In conclusion, MdPEPC1, MdPEPC2 and MdPEPC3 were selected as the candidate genes involved in axillary bud outgrowth regulation for further study.
Malus/metabolism*
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Gene Expression Regulation, Plant
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Phylogeny
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Decapitation
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Family
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Plant Proteins/metabolism*
4.Treatment of Respiratory Diseases with Banxia Houputang: A Review
Jiren AN ; Xinyue YANG ; Jixian SONG ; Qi CHEN ; Cuiling JIA ; Mengfan SUN ; Yashuo ZHAO ; Ensheng JI
Chinese Journal of Experimental Traditional Medical Formulae 2023;29(5):236-245
Respiratory diseases are common, frequently-occurring clinical diseases. As the prevalence rate is increasing year by year, they have become a problem that seriously affects public health. The diseases are mainly located in the lung by traditional Chinese medicine (TCM) syndrome differentiation. Lung governs Qi and controls breathing and is also an organ for the storage of phlegm. Clinically, phlegm and Qi are often used for the treatment. Banxia Houputang (BHT), originated from Synopsis of the Golden Chamber (《金匮要略》), was used to treat plum-stone Ai (globus hystericus) at first. It is composed of Rhizoma Pinelliae, Cortex Magnoliae Offcinalis, Poria, Rhizoma Zingiberis Recens, and Folium Perillae, and treats diseases with the core pathogensis of mutual obstruction of phlegm and Qi. BHT has the effects of moving Qi, dissipating mass, descending adverse Qi, and resolving phlegm, which basically correspond to the pathological characteristics of the lungs. Clinical studies have confirmed that modified BHT can be used either alone or in combination with western medicine to treat chronic pharyngitis, asthma, chronic obstructive pulmonary disease, pneumonia, obstructive sleep apnea, upper airway cough syndrome and other respiratory diseases, with significant effects. It effectively improves the symptoms and signs of the diseases and reduces the recurrence rate. Basic research has shown that BHT plays anti-inflammatory, anti-oxidative stress, anti-apoptotic, autophagy-regulating, and iron overload-regulating roles by regulating the targets in multiple pathways. This paper, by combing the relevant literature in recent years, conducted a systematic review on BHT from the three aspects of syndrome analysis, clinical treatment research and mechanism research, with a view to providing theoretical basis and reference for the mechanism research of BHT in treating respiratory diseases and for expanding its clinical application.