1.Research siblings identification by Identiffler system and automatic STR genetic
Yanxia GUO ; Yanrong KANG ; Wanshui LI ; Song CHEN ; Guochen ZHANG ; Kaihui LIU ; Yandong GUO ; Jiali LI ; Hongling GUO ; Jinping HAO ; Lu LIU ; Jian YE ; Xiaoyu XU ; Yuan OU ; Jian ZHANG ; Xiaojian LIN ; Hua WANG ; Yashen ZHAI ; Ruihua MI
Chinese Journal of Forensic Medicine 2009;24(6):368-371
Objective To evaluate the probability of siblings identification in Identifiler system by using the software of automatic analysis.Methods Using the software of automatic analysis in siblings jdentification.STP genetic typing of 151 pairs of full siblings and 31224 pairs of unrelated individuals from manual simulation were analyzed in 15 STR loci of ldentifiler system.Results Kin probability(W_(FS))of 39.07% full siblings were more than 99.999% while W_(FS) of unrelated individual pairs were 0% .W_(FS) of 60.93% full siblings and 21.3% unrelated individual pairs were all at the range from 99.999% to 1% .W_(FS) of 78.7% unrelated individual pairs 0% full siblings individuals were less than 1% .Therefore,there were notability difference between full siblings and unrelated individual pairs.In addition,testing of 15 STR loci of Identifiler system,it suggested that the pair were siblings when the locus number of the entirely-same is not less than 5 or that of the entirely-different is not more than 1,and that the pair were unrelated individuals when the locus number of the entirely-different is not less than 6 or that of the entirely-8alne is not more than 1.Conclusion The software of automatic analysis and the Identifiler system call be used to siblings identification.
2.Advances in the diagnosis and treatment of ureterosciatic hernia
Zhen ZHAO ; Fei LUO ; Yatong CHEN ; Yashen WANG ; Jian LI
Journal of Modern Urology 2024;29(4):375-378
Ureterosciatic hernia is a rare type of pelvic floor herniation with no typical symptoms. The resulting ureteral obstruction may lead to hydronephrosis and complications such as urinary tract infection and urosepsis.Fewer than 40 ureterosciatic hernia cases have been reported all over the world. Active surveillance, manual reduction, ureteral stenting and surgical repair are common treatment options. Among them, the safety and effectiveness of laparoscopic herniorrhaphy have been recognized. This article review the advances in the diagnosis and treatment of ureterosciatic hernia.