[Objective] To discuss the nursing to the common complications in perioperational period of lung cancer treated with ultrasonic guidance transdermal radiofrequency ablation(RFA). [Method] 12 cases of peripheral lung cancer treated with ultrasonic guidance transdermal RFA, took active mental nursing, closely cooperated in operation, strictly observed the disease condition after operation, had good nursing of perioperational period, and were strengthened on observation of complications and prevention. [Result] 12 cases had smooth operation, part of them had pain at puncture spot, fever, little aerothorax and hydrops, with blood in sputum at cough, and were relieved timely with active observation and clinical nursing, without other severe complications, final y they were discharged from hospital upon recovery, without death in perioperational period. [Conclusion] The ultrasonic guidance RFA is a safe and effective method to treat peripheral lung cancer with little invasion; the nursing point is to closely observe disease condition before and after operation, and do wel general nursing.

BACKGROUND:Mesenchymal stem cel s are the seed cel s for tendon tissue engineering which can be obtained in large quantities, but how to induce in vitro is a key technology.
OBJECTIVE:To explore the effect of platelet-rich plasma on the proliferation and col agen production of in vitro cultured mesenchymal stem cel s.
METHODS:The rabbit mesenchymal stem cel s were separated ad cultured. The high-dose platelet-rich plasma group, middle-dose platelet-rich plasma group and low-dose platelet-rich plasma group were set to induce the mesenchymal stem cel s, and the blank control group was set as control.
RESULTS AND CONCLUSION:The proliferation of mesenchymal stem cel s in the high-dose platelet-rich plasma group, middle-dose platelet-rich plasma group and low-dose platelet-rich plasma group was high, and in rapid growth with big increase amplitude, and there was no significant difference in the proliferation when compared with the blank control group (P<0.05). The effect was positively correlated with the culture time, and after cultured for a certain time, the effect was in dose-dependent manner, as higher dose platelet-rich plasma had more significant effect on the proliferation of the cel s. The results indicate that platelet-rich plasma can significantly promote the synthesis of col agen type Ⅰ and Ⅲ of mesenchymal stem cel s, the higher the dose, the more significant the effect on the col agen.

Objective To evaluate the value of magnetic resonance cholangiopancreatography(MRCP) in the diagnosis of biliary obstruction diseases by comparison with endoscopic retrograde cholangiopancreatography (ER-CP). Methods A total of 36 patients with biliary obstruction diseases underwent both MRCP and ERCP. To review the images obtained from ERCP and MRCP ,the diagnosis were compared according to pathology. MRCP and ERCP in the diagnosis and treatment of biliary obstruction disease were analysed. Results 36 patients including 16 biliary tumors, 15 cholelithiases,and five other diseases were analysed. The diagnosis accuracy of MRCP and ERCP for bil-iary obstruction diseases were 86.1% and 91.7 %, there was no significant difference( P > 0.05). Conclusion MR-CP can accurately define the obstructively sites, identify the obstructive causes and is a noninvasive and reliable exam-ination for biliary obstruction diseases.

Objective To compare the clinical effects and safety of olanzapine and aripiprazole in the treatment of schizophrenia .Methods From February 2015 to February 2017 ,100 patients with schizophrenia were chosen in the Third People's Hospital of Yuyao .The patients were randomly divided into A group ( treated with olanzapine ) and B group ( treated with aripiprazole ) , with 50 patients in each group .The clinical efficacy , PANSS score,blood lipid levels and blood glucose level before and after treatment ,and the incidence of adverse effects of the two groups were compared.Results The total effective rates of A group and B group were 86.00％,90.00％, respectively,there was no statistically significant difference between the two groups (χ2 =1.36,P>0.05).There were no statistically significant differences in the PANSS scores after treatment between the two groups ( t=3.17,2.96, 4.21,2.75,3.56,4.01,4.55,4.49,4.71,5.07,4.26,4.92,all P>0.05).After treatment,the levels of FBG,TC and TG of A group were statistically significantly higher than those before treatment (t=3.04,2.68,4.01,P<0.05). The levels of FBG,TC and TG after treatment of B group were significantly lower than those of A group (t=4.81, 3.35,4.14,all P<0.05).The incidence rates of lethargy ,dizziness,insomnia,nausea,vomiting and constipation of A group were 28.00％,38.00％,8.00％,6.00％,36.00％,respectively,which of B group were 2.00％,10.00％, 12.00％,8.00％,10.00％,respectively,and the incidence rates of lethargy ,dizziness and constipation of B group were significantly lower than those of A group (χ2 =9.32,8.77,10.24,all P<0.05),and there was no statistically significant difference in the incidence rates of insomnia ,nausea and vomiting between the two groups (χ2 =2.16, 1.12,all P>0.05).Conclusion Olanzapine and aripiprazole in the treatment of schizophrenia possess the same clinical effects and safety;but aripiprazole can efficiently relieve the influence of blood lipid metabolism and reduce the risk of adverse drug reactions .

Objective: To explore the mediating effect of the childbirth self-efficacy between mindfulness level and fear of childbirth in pregnant women. Methods: A total of 285 pregnant women were measured with five facet mindfulness questionnaire(FFMQ), childbirth attitude questionnaire(FOC), and the short form of the Chinese childbirth self-efficacy inventory(CBSEI-C32). Results: The scores of mindfulness level, fear of childbirth, outcome expectancy and self-efficacy expectancy were(127.51±11.12), (31.44±8.84), (109.36±30.52)and(110.02±30.03), respectively.Pearson correlation analysis showed that mindfulness level was positively correlated with outcome expectancy and self-efficacy expectancy(r=0.247, r=0.235, both P<0.01), while negatively correlated with fear of childbirth(r=-0.274, P<0.01). Outcome expectancy and self-efficacy expectancy were negatively correlated with fear of childbirth(r=-0.251, r=-0.233, both P<0.01). The mediating effect of outcome expectancy and self-efficacy expectancy between mindfulness level and fear of childbirth was significant(P<0.01), and the mediating effect sizes were 17.8% and 15.6%, respectively. Conclusion Childbirth self-efficacy partly mediates mindfulness level and fear of childbirth in pregnant women.