Objective To analyze the influence of individualized health education on self nursing ability of patients with colon stoma.Methods 120 patients with colon stoma were divided into the observation group and the control group,60 cases in each group.The patients of the control group were given conventional basic knowledge education,and the patients of the observation group were given personalized custom health education.Self score,health responsibility score,HAMD score,Barthel index,postoperative complications of the two groups of patients were compared.Results The observation group with self realization (32.16 ±7.25)points,health responsibility (28.62 ± 7.99)points,Barthel index (47.56 ±30.11 )points,HAMD score (3.15 ±1.44)points,stoma necrosis rate (1.67%)mucosal prolapse rate (0.00%),stoma retraction rate (3.33%)and stoma hernia rate (1.67%)were significantly better than the control group with self realization (27.98 ±9.53)points,health responsibility (24.87 ± 8.03)points,Barthel index (33.37 ±24.49)points,HAMD score (5.99 ±3.66)points,stoma necrosis rate (13.33%)mucosal prolapse rate (11.67%),stoma retraction rate (23.33%)and stoma hernia rate (15.00%), with statistically significant difference (t =2.71,2.56,2.83,7.56,χ2 =4.32,5.46,8.72,5.35,all P <0.05). Conclusion To implement personalized health education on health behavior of the patients with colon stoma has a positive role,to promote the stability of the patient's condition,strengthen the patient's awareness of disease,improve patient self -care ability,reduce the occurrence of complications.

A sophisticated effort is made to uplift the clinical nursing quality in hospitals, which aims at improving hospital nursing quality by means of enhancing the management functionality of the nursing department, enhancing nursing systems, implementing clinical paths, and quality service campaigns. These efforts are designed to effectively improve hospital nursing quality.

Hypofractionated conformal radiotherapy is capable to deliver much higher doses to the cancer than is possible with standard techniques. Recently there is data suggesting that the early stage nonsmall cell lung cancer ( NSCLC) which is not suitable to surgery is likely to benefit from this regimen, with low lung toxicity. Manyphase Ⅰ-Ⅱ studies showed that the patients with locally advanced NSCLC are well-tolerated to hypofractionated conformal radiotherapy. The model of radio-physic and relative clinical studies suggest that hy-pofractionation would not increase the risk of radiation pneumonitis compared to standard therapy.

OBJECTIVE:To establish the quality control standard of anticancer herbal suppository METHODS:The polygonaceae and cantharidin were qualitatively and quantitatively detected by TLC and UV-spectrophotometry respectively RESU_LTS:TLC was suitable for qualitative analysis of polygonaceae and UV-spectrophotometry for quantitative analysis of cantharidin CONCLUSION:TLC and UV-spectrophotometry can be used in quality control of this preparation

Objective To evaluate the efficacy and prognostic factors of radiotherapy in 162 patients with stage I and II non-small cell lung cancer(NSCLC).Methods Between December 1982 and August 1992, 168 patients with stage I and II NSCLC were treated, with 116 confirmed by histopathology and 52 by cytopathology. All patients received radiotherapy to a dose of 40-76 ?Gy and were followed up for more than five years. Results The overall 1-, 3- and 5-year survival rates were 67.6%, 28.0% and 15.7%. Absence of concurrent disease and Karnofsky performance status ≥80 were favorable prognostic factors. Conclusions Radiotherapy is effective for stage I and II non-small cell lung cancer patients who are contraindicated for surgery. Higher dose of radiotherapy is recommended to improve the local control and survival rate.

Objective To systematically evaluate the efficacy and safety of intracoronary abciximab administration as compared to intravenous in percutaneous coronary intervention (PCI) .Methods A search was conducted in PubMed ,EMBASE ,OVID ,CBM , CNKI and VIP for the randomized controlled trials (RCTs)of intracoronary abciximab administration versus intravenous in PCI , from the date of their establishment to September 30 ,2013 ,and the domestic relevant papers published in recent 1 year were also searched manually ,the bibliographies of the included studies were searched too .According to the criteria of the cochrane Hand-book ,two reviewers evaluated the quality of the included RCTs and extracted data independently ,and then the extracted data were analyzed by using RevMan 5 .1 software .Results 8 RCTs involving 10 articles with 4 150 patients who treated with PCI were in-cluded .The results of meta-analysis showed that :(1) Compared intravenous administration and intracoronary abciximab administra-tion ,there were no significant differences in the two groups for the major adverse cardiovascular event (MACE) and the mortality (OR=0 .78 ,95% CI 0 .54-1 .14 ,P=0 .20) ,(OR=0 .56 ,95% CI 0 .24-1 .30 ,P=0 .18) .(2)Compared with intravenous adminis-tration ,intracoronary abciximab administration were not associated with any excess of major bleeding complications :(OR=1 .26 , 95% CI 0 .78-2 .02 ,P=0 .35) .Conclusion Compared with standard abciximab regimen of intravenous bolus ,intracoronary admin-istration had equivalent effects in clinical outcomes in patients undergoing PCI ,and did not increase the incidence of bleeding events .

Objective To investigate the usage of oral cardio-cerebrovascular Chinese patent medicine in Tiantan Community Health Service Center of Beijing (hereinafter referred to as “the centre”) during 2010-2015. Methods Varieties, dosage and sales amount of oral cardio-cerebrovascula Chinese patent medicine during 2010-2015 were analyzed through hospital information system database of the centre. DDDs, DDC and B/A values were calculated. Results Oral cardio-cerebrovascular Chinese patent medicine accounted for 23.67% of all kinds of medicine during 2010-2015. The average annual growth rate of the amount of sales was 11.96%, accounting for 48.73% of total sales. DDDs showed an upward trend over six years, including DDDs of Compound Danshen Dirpping Pills ranking the first. DDC and B/A also showed the daily cost of most of oral cardio-cerebrovascular Chinese patent medicine was less than 10 yuan. B/A value was approximately equal to 1, indicating that these kinds of medicine had better synchronization, and high frequency of usage. Oral cardio-cerebrovascular Chinese patent medicine dominated in all kinds of Chinese patent medicine during 2010-2015, which was related to the reason that most patients were old people. The frequentness during 2010-2015 in the centre did not changed much, and the structure was relatively stable. Conclusion The usage of oral cardio-cerebrovascular Chinese patent medicine in the center is reasonable, with some problems, which need to be further supervised.

BACKGROUND:Shear mechanical properties of lumbar trabecular bone should be understood in treating osteoporosis,bone remodeling,bone reconstruction,as well as the choice of fracture fixed equipment.OBJECTIVE:To explore whether the shear mechanical properties of lumbar trabecular bone is different in young and aged normal fresh cadavers.METHODS:Experimental samples were from 4 normal fresh corpse,aged 22,28,70 and 75 years,were provided by Department of Anatomy,Norman Bethune Medical University.Spinal column thoracic vertebra L_2-L_5 specimen were obtained from corpse within 1 hour and cut into 40 min×5 mm×5 mm pieces.The specimen were tested on electronic universal testing machine with speed of 5 mm/min,the shear load,stress,strain and other data would be printed automatically,and the morphology of fracture surface was observed.RESULTS AND CONCLUSION:Majority of the fracture surfaces were comminuted,minority were transverse or oblique fracture.The macroscopic observation showed that trabecular arranged compact in the thoracic vertebra cancellous bone of the youth group,which was sparse arrangement and presented with senile osteoporosis in the aged group.The shear force,shear stress and strain of the youth group was greater than that of the aged group[(37.19±3.25),(28.34±3.42) N;(1.49+0.13),(1.13±0.14) MPa;(1.40±0.50)%,(0.90±0.20)%,P＜0.05].It demonstrated that the impact mechanics properties of thoracic vertebra cancellous bone are different between the youth and aged groups.

Objective To investigate cellular and behavioral effects of adenosine A2A receptor antagonist in a rat model of levodopa-induced motor complications.Methods The hemi-parkinsonian rat model was produced by stereotaxically injecting 6-OHDA to right medial forebmin bundle(MFB).Animals were intraperitoneally treated with levodopa 50 mg/kg plus benserazide 12.5 mg/kg twice a day for 22 days levodopa + vehicle.Rotational duration was estimated.After they were sacrificed,the expression of adenosine A2A receptor was observed by immunohistochemistry and Western blot.Results CSC,reversing the shortened rotational duration induced by levodopa,prolonged the rotational duration.This effect was maintained fil the end of the treatment.The chronic levedopa treatment induced an upregulation of adenosine A2A receptor expression in the lesioned striatum (IOD,(11.55±2.75)×104).The subsequent CSC treatment decreased the adenosine A2A receptor expression to the level of control (IOD,(6.02±1.29)× 104) and PD group (IOD,(5.60±1.83)×104>,F=33.31,P<0.05).Conclusion These results suggest that adenosine A2A receptor is probably involved in the development of levodopa induced motor complications and adenosine A2A receptor antagonist could be useful in the treatment of motor comphcations in parkinsonian patients.