2.Wells’ syndrome in an 18-year-old Filipino female: A case report
Jarische Frances S. Lao-Ang ; Claudine Yap-Silva
Journal of the Philippine Dermatological Society 2020;29(1):118-121
This is a case of an 18-year-old Filipino female with no known comorbidities, who presented with a three-year history of recurrent erythematous papules, vesicles, and nodules over her bilateral side of the chin. She was initially managed as a case of infected acne vulgaris, and was given oral antibiotics such as Cloxacillin, Rifampicin, and Clarithromycin, but with minimal improvement. She was then referred to Dermatology service for further evaluation. A 3-mm skin punch biopsy on an erythematous nodule on the left chin was done, and histopathologic findings were diffuse eosinophilic infiltrates, exhibiting flame figures admixed with few lymphocytes and neutrophils, consistent with Wells’ syndrome, otherwise known as eosinophilic cellulitis. Serology also revealed elevated IgE level at 949.2 IU/mL but normal eosinophil count. Patient was then given oral corticosteroid for eight weeks, resulting in complete resolution of lesions and no residual scarring.
Wells syndrome
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Cellulitis
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Eosinophilia
3.Validation of the Malay version of Autoimmune Bullous Disease Quality of Life (ABQOL) questionnaire
Evelyn Wen Yee Yap ; Kwee Eng Tey ; Premaa Supramaniam ; Dedee Murrell ; Siew Eng Choon
Malaysian Journal of Dermatology 2020;44(1):2-13
Autoimmune blistering diseases (AIBD) represent a group of rare and chronic disorders with significant
impact on quality of life (QoL). The aim of this study was to assess the validity and reliability of the
Malay translation of the autoimmune bullous disease quality of life (ABQOL) questionnaire.
4.Comparison of the clinical profile of patients with glaucoma between private and government clinics in the Philippines.
Edgar Felipe U LEUENBERGER ; James Paul S GOMEZ ; Robert Edward T ANG ; Maria Imelda YAP-VELOSO ; Joseph Anthony J TUMBOCON ; Jose Maria D MARTINEZ ; John Mark S DE LEON ; Nilo Vincent FLORCRUZ ; Rainier Victor A COVAR ; Irene R FELARCA ; Denise Polly CHAO-PO ; Shalam SIAO-MARIANO ; Marie Joan Therese D BALGOS ; Noel D ATIENZA
Philippine Journal of Ophthalmology 2019;44(2):45-53
OBJECTIVE: To describe the demographic and clinical characteristics of patients with glaucoma managed at private and government institutions in the Philippines between 2009 and 2014.
METHODS: A research team from two private and two government institutions in the Philippines reviewed the case records of 1246 patients seen who met the following criteria: intraocular pressure of >21 mmHg, optic nerve and nerve fiber layer abnormalities, and visual field defects. For bilateral cases, we selected the eye with worse glaucoma parameters.
RESULTS: There were 600 and 646 patients in the private and government groups (mean age at presentation, 60.51 and 55.88 years), respectively, with the majority being Filipino (91%). Patients with visual acuity (VA) of 20/20 to 20/40 were more frequently observed in private centers (58.7% vs. 41.3%), while a VA worse than counting fingers was more frequently observed in government centers (66.1% vs. 33.9%). Within-group analysis showed that primary angle-closure glaucoma was the most frequent glaucoma subtype in both private (27.3%) and government institutions (37.8%). In between-group analysis showed the following to be more common in private than government centers: primary open-angle glaucoma (61.3% vs. 38.7%), normal-tension glaucoma (63.9% vs. 36.1%), ocular hypertension (92.3% vs. 7.7%), and glaucoma suspects (80.4% vs. 19.6%) while government institutions registered a larger number of primary angle-closure glaucoma (59.8% vs. 40.2%) and secondary glaucoma (70.3% vs. 29.7%) cases. Medical treatment using a single drug and multiple drugs was employed for 245 (23%) and 825 (77%) patients, respectively. Within-group analysis showed that laser iridotomy and trabeculectomy were the most commonly performed laser and surgical procedures in both institution types.
CONCLUSION: There is a contrasting profile of glaucoma between clinical institutions in the Philippines with openangle glaucoma being more predominant in private centers while closed-angle glaucoma and secondary glaucoma being more frequent in government centers. Our findings may provide important preliminary information that can aid future health studies or training programs.
Human ; Glaucoma ; Patients
5.Can Paediatric Femoral Fracture Hip Spica Application be Done in the Outpatient Setting?
Yap ST ; Lee NKL ; Ang ML ; Chui RW ; Lim KBL ; Arjandas M ; Wong KPL
Malaysian Orthopaedic Journal 2021;15(No.1):105-112
children with femur fractures. This study compares the
outcomes of spica cast application, in terms of quality of
fracture reduction and hospital charges when performed in
operating theatre versus outpatient clinics at a local
institution.
Materials and Methods: A total of 93 paediatric patients,
aged between 2 months to 8 years, who underwent spica
casting for an isolated femur fracture between January 2008
and March 2019, were identified retrospectively. They were
separated into inpatient or outpatient cohort based on the
location of spica cast application. Five patients with
metaphyseal fractures and four with un-displaced fractures
were excluded. There were 13 and 71 patients in the
outpatient and inpatient cohort respectively who underwent
spica casting for their diaphyseal and displaced femur
fractures. Variables between cohorts were compared.
Results: There were no significant differences in gender,
fracture pattern, and mechanism of injury between cohorts.
Spica casting as inpatients delayed the time from assessment
to casting (23.55 ± 29.67h vs. 6.75 ± 4.27h, p<0.05),
increased average hospital stay (41.2 ± 31.1h vs. 19.2 ±
15.0h, p<0.05) and average hospital charges (US$1857.14 vs
US$775.49, p<0.05). Excluding the un-displaced fractures,
there were no significant differences in the period of cast
immobilisation and median follow-up length. Both cohorts
had a similar proportion of unacceptable reduction and
revision casting rate.
Conclusion: Both cohorts presented similar spica casting
outcomes of fracture reduction and follow-up period. With
spica cast application in operating theatre reporting higher
hospital charges and prolonged hospital stay, the outpatient
clinic should always be considered for hip spica application.
6.MMR trivalent vaccine based on safety, reactogenicity and immunogenicity observed in 12-24 month-old healthy Filipino children: Evaluation of lot-to-lot consistency of a live-attenuated measles-mumps-rubella
Salvacion Gatchalian ; Margaret Lu-Fong ; Leticia Cordero-Yap ; Jossie Rogacion ; Josefina Cadorna-Carlos ; Htay Htay Han ; Hans L Bock
Pediatric Infectious Disease Society of the Philippines Journal 2011;12(2):92-96
In this double-blind, randomized single-dose study, 194 healthy Filipino children aged 12-24 months were randomized into three groups (1:1:1) to receive one of the three lots of live-attenuated measles-mumps-rubella (MMR) vaccine to assess lot-to-lot consistency in safety and immunogenicity. Adverse events were recorded during 43-day post-vaccination follow-up period. Antibody levels were measured using ELISA pre-vaccination and on Day-60. No statistically significant differences were observed across groups for overall incidences of local and general symptoms (p>0.05) or immune response rates against the three antigens (p=0.835, 0.458 and 0.222 for anti-measles, anti-mumps and anti-rubella, respectively). The three lots demonstrated consistency in their reactogenicity and immunogenicity profile.
Human
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Male
;
Female
;
Infant
;
MEASLES-MUMPS-RUBELLA VACCINE
;
ENZYME-LINKED IMMUNOSORBENT ASSAY
7.Health Promotion Board-Ministry of Health Clinical Practice Guidelines: Falls Prevention among Older Adults Living in the Community.
Thilagaratnam SHYAMALA ; Sweet Fun WONG ; Akila ANDIAPPAN ; Kah Guan Au EONG ; Anu Birla BAKSHI ; Debbie BOEY ; Tsung Wei CHONG ; Hui Ping ENG ; Noor Hafizah ISMAIL ; Tang Ching LAU ; Wei-Yen LIM ; Hsin Wei Wendy LIM ; Lydia SEONG ; Wei Chin WONG ; Kai Zhen YAP ; Sri YUDAH
Singapore medical journal 2015;56(5):298-quiz 301
The Health Promotion Board (HPB) has developed the Clinical Practice Guidelines (CPG) on Falls Prevention among Older Adults Living in the Community to provide health professionals in Singapore with recommendations for evidence-based assessments and interventions for falls prevention. This article reproduces the introduction and executive summary of the key recommendations from the HPB-MOH CPG on Falls Prevention among Older Adults Living in the Community for the information of SMJ readers. The chapters and page numbers mentioned in the reproduced extract refer to the full text of the guidelines, which are available from the Health Promotion Board website: http://www.hpb.gov. sg/cpg-falls-prevention. The recommendations should be used with reference to the full text of the guidelines. Following this article are multiple choice questions based on the full text of the guidelines.
Accidental Falls
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prevention & control
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Aged
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Environment
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Evidence-Based Medicine
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Geriatrics
;
standards
;
Health Promotion
;
methods
;
Housing
;
Humans
;
Incidence
;
Middle Aged
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Practice Guidelines as Topic
;
Risk Assessment
;
methods
;
Singapore
;
Social Class