Objective To observe the influence of mental rehabilitation combined with family intervention on self -efficacy and quality of life of patients with schizophrenia.Methods 92 cases of schizophrenia patients were choosed to be the research object.They were divided into control group (46 cases)and observation group (46 cases) according to random number table method.The control group was given mental rehabilitation while the observation group was given the mental rehabilitation combined with family intervention treatment.The clinical efficacy of the two groups of patients was observed after six months.The patient's self -efficacy was assessed by using self -efficacy scale (GSES),and the patient's quality of life was assessed by using the quality of life scale (QLQ).Results Six months after treatment,the score of PANSS in patients with positive symptoms[(14.19 ±4.16)points],negative symptoms [(16.29 ±4.92)points],mental symptoms[(35.56 ±6.75)points]and total score[(65.84 ±15.83)points]in the observation group were lower,which were better than those of the control group[(17.37 ±5.27)points,(21.11 ± 5.64)points,(42.37 ±7.92)points and (80.85 ±18.83)points],and the differences were statistically significant(t =3.212,4.368,4.438,4.544,all P <0.05).The total effective rate was 86.96% in the observation group,which was significantly higher than 67.39% in the control group,the difference was statistically significant(χ2 =4.998,P =0.025).The self -efficacy scores of the two groups were higher than before the treatment,which of the observation group[(3.51 ±0.62)points]was better than that of control group[(2.13 ±0.48)points],the difference had statistical significance(t =5.593,P =0.000).After treatment,the patient's quality of life score such as emotional function [(59.82 ±11.38)points],cognitive function[(69.43 ±12.32)points],role function[(69.77 ±12.31 )points], physical function[(75.38 ±14.01 )points],social function[(66.28 ±13.03)points]and so on were higher than before treatment[(56.88 ±10.36)points,(42.01 ±9.29)points,(47.02 ±9.17)points,(60.34 ±10.89)points, (53.92 ±10.76)points].Results of the observation group were better than those of the control group[(53.07 ± 10.13)points,(63.02 ±11.17)points,(62.03 ±11.17)points,(67.33 ±11.74)points,(60.87 ±12.62)points], the differences had statistical significance(t =3.005,2.664,3.158,2.987,2.023,all P <0.05).Conclusion Therapy of mental rehabilitation combined with family intervention can improve the clinical curative effect of schizophrenia patients, and improve the patient's self -efficacy and quality of life.It is worthy of clinical popularization and application.

Objective To observe and explore the effect of aripiprazole(Ari)and olanzapine(Ola)on body weight and lipid metabolism in schizophrenia(SP)patients.Methods 96 patients with SP were randomly divided into two groups,48 cases in the observation group and the control group.The control group was treated with Ola,while the observation group was treated with Ari.Before and 6 weeks after treatment,the height,body weight,blood glucose (FBG),insulin(INS),low -density lipoprotein(LDL),triglycerides(TG),total cholesterol(TC)levels in the two groups were detected,insulin resistance index(IRI)and BMI were calculated.Results The differences of body weight,BMI,FBG,INS,IRI,LDL,TG,TC before treatment between the two groups were not statistically significant (t =0.161,0.564,0.277,0.078,0.092,0.124,0.421,0.245,all P >0.05).After 6 weeks treatment,FBG,INS, IRI in the observation group were (4.71 ±0.58)mmol/L,(21.85 ±12.36)μU /mL and (4.62 ±2.14),the differ-ences were not statistically significant compared with before treatment(t =0.800,0.571,0.276,all P >0.05).Those in the control group were (5.14 ±0.56)mmol/L,(28.54 ±11.25)μU /mL and (6.23 ±3.82),which were signifi-cantly higher than those before treatment(t =4.898,3.361,2.628,all P <0.05),and were also significantly higher than those in the observation group(t =3.695,2.773,2.547,all P <0.05 ).After 6 weeks treatment,the body weight,BMI,LDL,TG,TC in the observation group were not statistically significant compared with before treatment (t =0.262,0.638,0.124,0.421,0.245,all P >0.05 ),those in the control group were significantly higher than before treatment(t =2.601,3.834,5.773,5.838,4.375,all P <0.05),and were also significantly higher than those in the observation group(t =3.052,3.265,5.264,5.496,4.188,all P <0.05).Conclusion Ari treatment for SP has no significant effect on glucose and lipid metabolism and body weight in patients,and the effect of Ola treatment on patients'body weight and lipid metabolism is more significant.

Objective The epidemiological characteristics of high-altitude pulmonary thromboembolism (PTE) were investigated, and to enhance people's cognitive level of high-altitude PTE. Methods A tatal of 286 patients with PTE admitted to our hospital from May 2017 to October 2019 were selected and divided into study group (n = 143) living at high altitude of 2500 ~ 4500 m and control group (n=143) living at low altitude of 1500~2450m according to altitude.The clinical data, D-D, FIB levels, and laboratory routine examinations were compared between the two groups, and the risk factors were analyzed using univariate analysis and the independent risk factors were analyzed by multivariate logistic regression. Results The levels of D-D and FIB in the control group were significantly increased (P<0.05). Univariate analysis showed that high altitude polycythemia, hemoglobin, hypoxemia, pulmonary hypertension, D-D level, FIB level, lower extremity deep venous thrombosis, pulmonary heart disease, dyspnea and chest pain were all risk factors of PTE at high altitude. Multivariate logistic regression analysis showed that red blood cell count, HGB level, increased hemoglobin concentration, DVT and D-D level were independent risk factors of PTE at high altitude. There was no significant difference in the general data (gender, age, occupation) between the two groups (P > 0.05). Conclusion  Those were independent risk factors affecting the incidence of PTE at high altitude，including multivariate logistic regression analysis indicated that red blood cell level, HGB level, DVT, D-D, and FIB. The higher the plasma D-D and FIB levels, the recurrence interval, especially the related diseases of patients at high altitude need regular monitoring.

Objective:To evaluate the clinical application effects of a domestic bone-level implant system for restoring single tooth loss, and provide clinical evidence for the promotion and application of domestic implants.Methods:A prospective, multicenter clinical trial was conducted from April 2018 to January 2020 in three institutions: Department of Oral Implantology, School & Hospital of Stomatology, Wuhan University, Department of Stomatology, The First Affiliated Hospital of Zhejiang University School of Medicine, and Department of Stomatology, The Third Hospital of Hebei Medical University. The trial planned to include 100 patients for single tooth implantation and restoration, followed up for 1 year, to evaluate the implantation success rate and other related outcomes.Results:This study screened a total of 142 patients and ultimately included 100, comprising 43 males and 57 females with age of (47.0±12.2) years. Ninety-eight out of 100 patients completed a one-year follow-up (98.0%), while 2 patients terminated the trial early due to implant loosening (2.0%). After a one-year follow-up, the implants of the 98 patients were all functioning successfully, with a success rate of 98.0% (98/100). The patients were satisfied with the overall restoration effect.Conclusions:This study indicates that the domestic bone-level implant system has achieved favorable short-term clinical outcomes for single-tooth implantation and restoration.