Objective To investigate the clinical,imaging (CT and MRI) and pathological features of intracerebral inflammatory pseudotumour. Methods The clinical, neuroimaging and neuropathological data of a patient with intracerebral inflammatory pseudotumour were analyzed retrospectively. Results The manifestations of this patient included headache, nausea, vomiting, fever and seizures. Brain MRI showed abnormal high T1 and T2 signals in the right frontal lobe and midline shift. The resection pathology showed brain tissue swelling, loss of normal neuron outline, massive inflammatory infiltrations in perivascular spaces. Although the patient was treated with operation, dehydration and antibiotics, he died eventually.Conclusions Intracerebral inflammatory pseudotumour is an unusual disease in clinical practice. This disease is diagnosed mainly depended upon pathological examinations because of no specific clinical and imaging manifestations. The prognosis is not good although operative treatment is performed.

Objective: To investigate the clinical and pathological features of patients with cerebral amyloid angiopathy (CAA) related cerebral hemorrhage (C A AH). Methods : The clinical data of 5 patients with C A AH, including clinical manifestations, neuroimaging and topographical anatomy features were studied. Results: It was found that the onset and clinical manifestations of CAAH resembled hypertensive cerebral hemorrhage. CAAH could coexist with hypertension and hypertension might aggravate the pathological changes of CAA. Typical CAAH located in cortical and subcortical areas, but cerebral hemorrhage located in the basal ganglia and thalamus could not ruled out CAAH without the pathological confirmation of CAA. The neuroimages of some specific types of cerebral hemorrhage, such as insular cistern hematoma and subarachnoid hemorrhage, could manifest as hypertonial putaminal hemorrhage, but their outcomes were distinctly different. Conclusion: The causes of cerebral hemorrhage include hypertension and cerebral amyloid angiopathy, and CAA may have an important clinical value.

Objective: To evaluate the residual radioactivity after ¹³¹I treatment in postoperative inpatients with differentiated thyroid carcinoma (DTC) using service robot in nuclear medicine ward, and assess the time for patients to be released from isolation. Methods: From September 2017 to June 2018, 297 patients (94 males, 203 females, age: 19-80 years) with DTC who underwent ¹³¹I treatment after surgery were included. According to the purpose of treatment and the prescription dosage of ¹³¹I, patients were divided into 8 groups: 4 groups accepted ¹³¹I remnant ablation therapy (RAT) with different dosages, which were 3 700 MBq (RAT1, n=34), 4 440 MBq (RAT2, n=122), 5 550 MBq (RAT3, n=81) and 7 400 MBq (RAT4, n=27), respectively; 4 groups had ¹³¹I treatment for recurrent/metastatic lesions (RMLT), and the dosages were 3 700 MBq (n=1), 4 440 MBq (n=2), 5 550 MBq (n=14) and 7 400 MBq (n=16). At 4, 24, 48 and 72 h after ¹³¹I administration, the dose equivalent rates at 2 cm away from the patient′s neck and at 1 m away from the body were measured by the robot designed for nuclear medicine ward. Kruskal-Wallis rank sum test and Mann-Whitney U test were used to analyze the data. Results: Neck dose equivalent rates for patients with RAT at different time points (4, 24, 48 and 72 h) after ¹³¹I administration were significantly different among 4 groups (H values: 20.889-46.410, all P<0.05), as well as the body dose equivalent rates (H values: 27.181-35.497, all P<0.05). The neck dose equivalent rates at 24, 48 and 72 h after ¹³¹I administration were statistically different between group 3 and 4 for patients with RMLT (z values: 2.328-3.076, all P<0.05; data in group 1 and 2 were too limited to be compared), while there was no statistical difference for the body dose equivalent rates (z values: 0.333-1.621, all P>0.05). The radioactivity retention in patients decreased rapidly within 24 h, then slowed down gradually and became extremely low at 72 h. At 72 h after ¹³¹I administration, 96.6%(255/264) patients with RAT and 100%(33/33) patients with RMLT were lower than 23.3 μSv/h, which meant the patients could be discharged from hospitalization. Conclusions Nuclear medicine ward service robots may dynamically measure residual radioactivity in DTC patients who take ¹³¹I treatment, providing individualized isolation solutions.