1.The type Ⅴ bone contusion of knee: MRI diagnosis and clinical significance
Yaoqu HUANG ; Shouguo ZHOU ; Xianwei PAN
Chinese Journal of Radiology 2010;44(2):172-175
Objective To explore the MRI appearances of type Ⅴ bone contusion of knee, and explore the diagnostic value and clinical significance of MRI. Methods A retrospective review of 1672 consecutive MRI examinations of acutely injured knees was performed to screen patients with type Ⅴ bone contusion. The MRI findings of them were analyzed by two musculoskeletal radiologists. Results The type Ⅴ bone contusion of knee was found in 43 (2.6%)patients, involving both the inferomedial patella and the anterolateral femoral condyle. Bone contusion was defined as low signal on T_1WI, intermediate or slight hypointense signal on T_2WI,and high signal intensity on fat saturation PDWI, which could be easily detected on axial, sagittal or coronal MR images. Other concomitant specific MR findings included fracture in 9 patients, chondral injury in 29 patients, and lateral patellar subluxation or complete dislocation in 27 patients. Injury of the medial retinaculum was diagnosed and classified in 37 cases, which could be observed best on axial images. Conclusions MRI was accurate in detecting the type Ⅴ bone contusion and that is very helpful for diagnosis and treatment of transient lateral patellar dislocation,and should be used as a routine examination for knee trauma. Axial MR examination should be performed to evaluated the medial patellar retinaculum injury when type Ⅴ bone contusion was found.
2.Study on changes of cytokines in patients with acute pancreatitis
Caoqun HUANG ; Weidong ZHU ; Yaoqu ZHONG ; Canli YE
Chinese Journal of Primary Medicine and Pharmacy 2009;16(7):1157-1158
Objective To study the clinical significance and changes of serum TNF-α、IL-6、IL-8、PAFand AGT-Ⅱ in patients with severe acute pancreatitis(SAP). Methods Serum TNF-α、IL-6、IL-8、PAF、AGT-Ⅱ values of all patients were measured by ELISA and radioimmunoassay. 30 cases with mild AP(MAP group),50 cases with SAP(SAP group) and 30 non-pancreatitis patients as control group. Results The level of TNF-α, IL-6, IL-8, PAF, AGT-Ⅱ of acute phase and recovery phase in SAP group and the MAP group were significantly higher than the normal control group(all P < 0.01); the level of TNF-α、IL-6、IL-8、PAF and AGT-Ⅱ of acute phase in SAP group were significantly higher than the MAP group(all P <0.05); the level of TNF-α、IL-6、IL-8、PAF and AGT-Ⅱ of re-covery phase in SAP group were significantly lower than the acute phase(all P <0.05);the level of TNF-α、IL-6、IL-8、PAF and AGT-Ⅱ of died in SAP group were significantly higher than the survivors (all P < 0.05~0.01). Conclu-sion The level of TNF-α、IL-6、IL-8 with the severity of SAP's condition and prognosis is closely related, The level of AGT-Ⅱ in SAP group were significantly higher than the MAP group.
3.Application of dynamic APACHEⅡscore and POSSUM score in patients with severe acute pancreatitis
Weidong ZHU ; Weiye GAO ; Manyue ZHENG ; Yaoqu ZHONG ; Chaoqun HUANG
Chinese Journal of Primary Medicine and Pharmacy 2009;16(2):225-226
Objective To discuss the value of combining the physiological and operative severity score for enumeration of mortality and morbidity(POSSUM)and acute physiology and chronic health evaluation Ⅱ(APACHE Ⅱ)in severe acute pancreatitis(sAP).Methods 60 cases of SAP were divided into surgery group(n=15)and non-surgical group(n=45),Non-surgical group was vahde with APACHE Ⅱ score,the surgery group with POSSUM score,decided to continue conservative treatment or surgery treatment,Observation of two ways with the complications and death.Results The rates of compHcafions and death were(0.37±0.08)and(0.27±0.09)in Single-operation group(n=15)higher than(0.76±0.14)and(0.61±0.15)in surgical group(n=11)(t1=3.125,t2=3.211,P<0.01);APACHEⅡ score of mortality in operation group and non-surgical group were no significant difference(x2=2.28,x2=1.98,P>0.05);APACHE Ⅱ score were(10.12±6.27)in survival group(n=46)were lower than (25.75±7.90)in death group(n=14)(t=2.525,P<0.05.Conclusion The score of dynamic APACHE Ⅱ has better effect to judge the timing of surgery,and the score of POSSUM has high value to predict post-operative complications and deaths occurred in patients with severe acute pancreatitis.
4.MRI features and differential diagnosis of real and pseudo-tears of lateral meniscus at the insertion site of meniscofemoral ligament
Yaoqu HUANG ; Xiaomei ZHAO ; Qionghui WU ; Yonggen ZOU
Chinese Journal of Radiology 2016;50(4):269-273
Objective To analyze MRI features of real tears and pseudotears of posterior horn of the lateral meniscus (PHLM) at the insertion site of meniscofemoral ligament(MFL), and to discuss main points of differential diagnosis. Methods MR images of 32 patients with PHLM tears and 30 patients with anterior cruciate ligament tears but without PHLM tears confirmed by arthroscopy were analyzed retrospectively. Another 20 asymptomatic volunteers as controls underwent MR examination and analyzed. The number of consecutive slices displaying longitudinal increased signal in sagittal images and the length in axial images were evaluated. The one?way analysis of variance, χ2 test and ROC curve were used to analyze diagnostic value of different MRI findings. Results Longitudinal line with abnormal increased signal (pseudotear) was found in 82.0% (41/50) normal insertion site of MFLs. The typical MRI finding of real tears was peripheral longitudinal linear high signal in PHLM which reached the margin of articular surface. In sagittal images, longitudinal linear high signal was shown in (5.8 ± 1.2) slices in knees of real tears, which was more than (2.6±1.1) slices and (2.7±1.4) slices in pseudo?tear groups (F=60.9, P<0.01). The area under ROC curve was 0.96 for differentiating real tear from pseudo-tear using the number of consecutive slices displaying longitudinal increased signal in sagittal images. With a threshold of five or more consecutive images with abnormal longitudinal increased signal as the positive standard of continuous?line sign, the overall sensitivity, specificity and accuracy for diagnosing real tear were 90.6%(29/32), 90.2%(37/41) and 90.4%(66/73), respectively. The axial images showed that the length of increased signal line in the outer of PHLM was (16.4±4.9) mm in patients with real tears, which was longer than pseudo?tear groups with length of (8.1 ± 3.2) mm and (6.0 ± 3.1) mm (F=17.0, P<0.01). The area under ROC curve was 0.92 for differentiating real tear from pseudo?tear using the length in axial images. The zip sign was defined when its length was not less than 10 mm. The sensitivity, specificity and accuracy of the zip sign was 84.4%(27/32), 90.2%(37/41) and 87.7%(64/73) respectively. In coronal images, high signal of MFL attachment insertion was shown in 71.9%(23/32), 60.0%(15/25) and 10/16 cases, there was no significant difference (χ2=0.98, P=0.61). Conclusion The continuous?line sign and zip sign are characteristic findings of PHLM tears at the insertion site of MFL attachment, which are valuable for differential diagnosis with pseudotears at the insertion site of MFL.