Objective To determine the sensitivity and accuracy of CT do ub le-contrast arthrography (CTA) in detecting underlying soft-tissue and bony abno rmalities of recurrent anterior glenohumeral dislocations. Methods From March 19 90 to May 2003, 31 patients with the signs and symptoms of recurrent anterior in stability, which were 23 males and 8 females with an average age of 26.7 years ( ranging, 22 to 46 years), were recruited for the study. All patients suffered fr om more than three times of glenohumeral dislocations, underwent CT arthrography after intraarticular injection of air and radiographic contrast medium before o peration. The surgical procedures included open Bristow operation in 25, Bankart operation in 3, Putti-Platt operation in 2, and a combination of Bankart and ca psular tightness operation by arthroscopy in 1. Each patient also underwent arth roscopy or open surgery and the observations were compared with CTA. Results Les ions of labrum and capsulo-ligamentous complex were the two most common abnormal ities demonstrated by surgical findings, which were respectively found in 28 and 20 patients at surgery. Anterior glenoid labral abnormalities, including of tea r, detachment, degeneration, were detected on CTA in 26 of 28, 2 of glenoid labr al degeneration were undetected on CTA, and the accuracy rate diagnosis on CTA w as 93.5%, while the sensitivity of CTA was 92.8%. Capsular lesions, including of marked medial scapular insertion, glenoid marginal stripping, and loss of inter vening scapular marginal soft tissues, were detected on CTA in 19 of 20, 1 of ca psular glenoid marginal stripping was undetected on CTA, and the accuracy rate d iagnosis on CTA was 87.1%, while, the sensitivity of CTA was 95%. Subscapularis tendon abnormalities, including of tears and irregularities, were visualized in 7 cases on CTA, but only 4 of which were identified during surgery. Furthermore, all of 15 Hill-Sachs defects, 6 Bankart bony defects, and 1 rupture of supraspi natus tendon suggested by CTA, were identified during surgery. For 26 of the pat ients with above kinds of lesion resulting in recurrent anterior glenohumeral di slocation, the accuracy rate of diagnosis was 83.7%. Conclusion The utilization of CT double-contrast arthrography can improve the understanding of multiple les ions associated with recurrent shoulder dislocation, it is contributed to select proper operative procedure.

Objective To evaluate the efficacy of arthroscopic capsular release of frozen shoulder.Methods Twenty-five patients with frozen shoulder were treated arthroscopically from October 2001 to October 2003 in this hospital.The operation was performed under general anesthesia.The arthoscope was inserted through a posterior approach and the radiofrequency electrotome was inserted via an anterior approach.The synovitis of the biceps tendon and the rotator interval was thermo-coagulated.The superior glenohumeral ligament,the middle glenohumeral ligament,and the intra-capsular part of subscapularis tendon were cut to release the capsule.The combination manipulation was performed to release the residual contracture.The range of motion of the shoulder and the American Shoulder & Elbow Surgeons(ASES) scores were recorded at 3 and 6 postoperative months,respectively.Results The operative time was 75~95 min(mean,85 min).No intraoperative complications were found.As compared with preoperative conditions,the motion of inward rotation revealed no significant improvement at 1 week after operation(?~2=8.558,P=0.073) and other shoulder motions were significantly improved at different postoperative stages(P0.05).Conclusions Arthroscopic release for the treatment of frozen shoulder may obviously shorten the period of the disease and obtain good curative effects.

AIM: To detect free and hydrolysable gallic acid in Acer Truncatum Bunge by HPLC. METHODS: A method for determining gallic acid in leaves of Acer Truncatum Bunge.The operating conditions HPLC were Diamonsil C_18 column(5 ?m,4.6 mm?250 mm) at room temperature,methanol-0.025 mol/L phosphoric acid solution(15∶85) as mobile phase at a flow of 1.0 mL/min and UV detection at 272 nm. RESULTS: The contents of free and hydrolysable gallic acid were 0.045% and 1.546%,repectively.The relative standard deviations of free and hydrolysable gallic acid were 1.06% and 2.43%,respectively. CONCLUSION: The contents of free and hydrolysable gallic acid in Acer Truncatum Bunge in different periods are different.

Objective To observe the pathologic type and degree of traumatic recurrent anterior dislocation of the shoulder by means of arthroscopy and discuss clinical results of modified Bristow method and arthroscopic Bankart reconstruction so as to provide refeFences for selecting operation methods.Methods A retrospective study was done off 62 patients(62 shoulders,44 males and 18 females.at av-erage age of 39.8 years.ranging from 21 to 67 years)with anterior recurrent dislocation of shoulder (mean duration of 87 months)admitted into our hospital from July 1997 to Oetcher 2007.All patients un-derwent preoperative arthroscopic examination that showed pathologic changes including injury of shoulder and humerus head,Bankart injury severity and laxitas of humerus glenoid ligament of articular capsule,which were used as referenee of surgical procedures.Modified Bristow's method or arthroscopic suture anchor Bankart reconstruction were performed according to arthroscopic results(pathologic change).The patients were assessed with the University of California at Los Angeles(UCLA)shoulder rating scale.Results There were 45 patients treated with modified Bristow,s method and 17 with arthroscopic suture anchor Bankart reconstruction.The follow.uD for mean 64.2 months showed that pre-and post-operative mean UCLA scores were(22.6±4.4)points and(29.8±4.2)points respectively(P＜0.01),the mean forward flexion(136.8±14.2)°and(156.6±17.8)°respectively(P＜0.01)and the mean ex-ternal rotation in 90°abduction(52.5±16.4)°and(72.4±11.3)°(P＜0.01).There were no redis-location at final follow-up,but there were 6 patients(9.6%)with positive apprehension test.Of all,60 patients(97%)returned to their pre-injury.work. Conclusions Observation of pathologic change of surgical procedure.Both modified Bristow's method and arthruscopic Bankart reconstruction are good methtxts for treatment of recurrent anterior shoulder dislocation under conditions of successful management of pathologic change of shoulder, restoration of normal anatomic structure of shoulder ioint and strict indi-cation control.

Objective To retrospectively analyze the mid-term functional outcome and quality of life in elderly patients undergoing the mobile-bearing versus fixed-bearing total knee arthroplasty.Methods Patients aged over 65 years who underwent total knee arthroplasty during January 2002 to December 2010 were followed up.The knee joint function was assessed by Western Ontario and McMaster Universities (WOMAC) score.Quality of life was assessed by using SF-16 (Short Form36) questionnaire.Data of mobile-bearing versus fixed-bearing groups were statistically analyzed.Results 157 cases (194 knees) were followed up completely.The mean follow-up period was (5.06±2.47) years (range 2.08-10.75 years).The mean age was (72.4±4.3) years (range 65-86 years old).Preoperative versus postoperative WOMAC scores were (48.2 ± 14.9) vs.(10.7±9.1) (P＜0.01).There was no significant difference in WOMAC score between the fixed-bearing group and the mobile-bearing group during the follow up [(10.12±8.76) vs.(11.38±9.55),t=0.861,P＞0.05].The mean SF-36 score was (119.65± 12.03) in the overall population of patients,which showed no significant difference as compared with the good and moderate optimal truncation value of 117 (t =2.759,P＞0.05).There was no significant difference in SF-36 score between the fixed-bearing group and the mobile-bearing group [(120.17±11.06) vs.(119.06±13.07),t=0.575,P＞0.05].Conclusions Total knee arthroplasty can improve the knee joint function and quality of life in elderly patients with severe knee osteoarthritis.For the elderly,the mid-term functional outcome and life of quality are similar in the mobile-bearing and the fixed-bearing total knee arthroplasty,and any kind of prostheses can be chosen to use,

Footballer 's ankle is anterior bony spur or anterior impingement symptom of the ankle with anterior ankle pain, limited and painful dorsiflexion. The cause is commonly seen in athletes and dancers, and is probably due to repetitive minor trauma. The condition was firstly described by Morris; McMurray reported good results from excision of the spurs, naming it footballer' s ankle. Opening resection of osteophytes of the anterior tibial and superior talar is an effective treatment for anterior impingement of the ankle.
Adult ; Ankle Injuries ; etiology ; Athletic Injuries ; etiology ; Football ; Humans ; Male

Objective To evaluate the T lymphocyte functions in elderly patients following major orthopedic operation. Methods From May 1998 to Feb 1999, 39 elderly patients (65 95 years old) hospitalized for orthopedic operation were studied. The patients' peripheral blood samples in the experimental group were obtained on days 1, 3, 7 and 14 postoperation, respectively. At the same days, blood samples were taken from 15 elder patients without trauma and operation (65 80 years old) within 6 months as controls. T lymphocyte subpopulations were differentiated by means of quantitative assay with autocounting method of FCM. Results CD3 T cell count was significantly decreased on day 1(54 4?11 3)% and day 14(58 5?12 6)%, compared with controls (63 9?8 3)% ( P

Breast cancers are the most common malignant tumors in women, and how to use ultrasound to diagnose breast cancers quantitatively is stil an unsolved problem. This paper extracts five elastic features based on the elastography images of the breast tumors, furthers extract four features related to gray co-occurrence matrix to describe the texture of breast masses. we study the application of SVM classifier to classify these features, and uses the consistency, classification accuracy, ROC curve and AUC (area under the curve) to assess the classification results. we used ultrasound imaging technique to colect data from the actual patients, with the data of 195 lesions in 142 patients. Experimental results show that the classification performance of the elastic features is good, and the support vector machine is suitable for breast image classification, and its classification accuracy is high, which provides a good value for diagnosis. Meanwhile, it is found that the extracted features related to gray level co-occurrence matrix have a low diagnostic value.

This study aims to investigate the effects of fibroblast growth factor 21 (FGF-21) on learning and memory abilities and antioxidant capacity of D-galactose-induced aging mice. Kunming mice (37.1 +/- 0.62) g were randomly divided into normal control group, model group and FGF-21 high, medium and low dose groups (n = 8). Each group was injected in cervical part subcutaneously with D-galactose 180 mg x kg(-1) x d(-1) once a day for 8 weeks. At the same time, FGF-21-treated mice were administered with FGF-21 by giving subcutaneous injection in cervical part at the daily doses of 5, 2 and 1 mg x kg(-1) x d(-1). The normal control group was given with normal saline by subcutaneous injection in cervical part. At seventh week of the experiment, the learning and memory abilities of mice were determined by water maze and jumping stand tests. At the end of the experiment, the mice were sacrificed and the cells damage of hippocampus was observed by HE staining in each group. Reactive oxygen species (ROS), malondialdehyde (MDA), superoxide dismutase (SOD), glutathione peroxidase (GPx), catalase (CAT) and total antioxidant capacity (T-AOC) in the brain of mice were determined. The results showed that different doses of FGF-21 could reduce the time reaching the end (P < 0.01 or P < 0.05) and the number of touching blind side (P < 0.01 or P < 0.05) in the water maze comparing with the model group. It could also prolong the latency time (P < 0.05) and decrease the number of errors (P < 0.01 or P < 0.05) in the step down test. The result of HE staining showed that FGF-21 could significantly reduce brain cell damage in the hippocampus. The ROS and MDA levels of three different doses FGF-21 treatment group reduced significantly than that of the model group [(5.58 +/- 1.07), (7.78 +/- 1.92), (9.03 +/- 1.77) vs (12.75 +/- 2.02) pmol (DCF) x min(-1) x mg(-1), P < 0.01 or P < 0.05], [(2.92 +/- 0.71), (4.21 +/- 0.81), (4.41 +/- 0.97) vs (5.62 +/- 0.63) nmol x mg(-1) (protein), P < 0.01]. Comparing with the model group, the activities of SOD, GPx, CAT and T-AOC of the three different doses FGF-21 treatment groups were also improved in a dose-dependent manner. This study demonstrates that FGF-21 can ameliorate learning and memory abilities of D-galactose induced aging mice, improve the antioxidant abilities in brain tissue and delay brain aging. This finding provides a theoretical support for clinical application of FGF-21 as a novel therapeutics for preventing aging.

Ultrasonic plane wave imaging is one of the hot topics in the study of ultrasound imaging, but the plane wave ultra-high frequency ultrasound has brought a large amount of data. If these data are transmitted directly through the hardware, it will not only bring a great burden on the hardware, but also put a requirement for the ability of the hardware processing data. In order to reduce the problem caused by the high frame frequency and large amount of data, the data compression methods are used to reduce the amount of data acquisition and transmission. In this paper both lossy compression and lossless compression are studied, where LZW compression algorithm is chosen to test lossless compression effect, and based on the plane wave characteristics, the frequency domain cutting compression algorithm is developed as a lossy compression method. In this paper, the LZW algorithm is implemented in FGPA, and it can achieve a certain compression ratio after testing the ultra sonic simulation data. Under the condition of known fractional bandwidth, it is found that the main bandwidth can be preserved in the spectrum, while the rest of the frequency signal has little effect on the image. By testing the ultrasonic simulation data, the frequency domain cutting algorithm can achieve high compression ratio, and the difference between the original image and the reconstructed image is relatively smal . So from the point of the compression ratio, the frequency domain cutting algorithm is the primary choice of the ultrasonic data compression algorithm.