BACKGROUNDLiposarcomas, which represent 20% of all adult sarcomas, are the most common histological type of malignant soft tissue tumors. The aim of this study was to define the prognostic factors that predict the postoperative survival period for patients with primary retroperitoneal liposarcoma.

METHODSThe clinical data and prognoses of 71 patients with primary retroperitoneal liposarcoma who were treated in the General Hospital of the People's Liberation Army of China between January 1, 2000 and December 31, 2007 were retrospectively reviewed and analyzed.

RESULTSThe primary tumor from each patient was resected; 54.9% (39/71) were deemed R0 resections, 31.0% (22/71) were R1 resections and 14.1% (10/71) were deemed R2 resections (palliative operations). The median follow up was 68 months (range: 1-160 months). Of the patients who received an R1 or R2 resection of their primary tumor, 96.7% (59/61) had tumor recurrence. The 1-year, 3-year, and 5-year recurrence-free rates were 77.0%, 29.8% and 19.7%, respectively. As of April 2013, 53 of the 71 patients had died from tumor recurrence. The overall 1-year, 3-year, 5-year, and 10-year survival rates were 88.7%, 76.1%, 61.7%, and 30.4%, respectively. The factors that were significantly associated with prognosis in the univariate analysis were age (as a categorical variable) (P = 0.006), modus operandi (P = 0.000), histologic subtype (P = 0.000), tumor grade (P = 0.000), ascites (P = 0.000), postoperative metastasis (P = 0.000) and adjuvant therapy (P = 0.030). However, in the multivariate analysis, the modus operandi (P = 0.000), tumor grade (P = 0.006), ascites (P = 0.027), postoperative metastasis (P = 0.023) and age (as a categorical variable) (P = 0.002) were the only significant predictors of survival.

CONCLUSIONSComplete resection remains the most effective method for treating liposarcoma. High grade, old age (≥ 60 years old), postoperative metastasis, and ascites predict poor prognoses.

Adult ; Aged ; Aged, 80 and over ; Female ; Humans ; Liposarcoma ; surgery ; Male ; Middle Aged ; Neoplasm Recurrence, Local ; surgery ; Prognosis ; Retroperitoneal Neoplasms ; surgery ; Retrospective Studies ; Young Adult

Objective To study the nursing of digital subtration angiography and embolization treatment in the patients with retroperitoneal tumor .Methods Clinical data of 74 patients with retroperitoneal tumor (74 patients underwent digital subtration angiography , 54 patients underwent digital subtration angiography and embolization treatment ) were analyzed retrospectively .Results Totals of 54 patients received angiography and positive cases were treated with interventional embolization .All of the 54 patients had no ectopic artery embolism , puncture site hemorrhage and infection , 23 cases had fever after embolization ,16 cases had different levels of low back pains;15 cases were abdominal pains , 4 cases were urinary retention .Conclusions Angiography can clearly display the tumor blood supply , peripheral blood vessels and organ relationships in retroperitoneal tumor . Interventional embolization can effectively reduce the bleeding during the operation and the size of tumor , so these methods can decrease the blindness and risk of operation .The key job of nursing is to prepare for operation before angiography and interventional embolization , closely observe the changes of patients after angiography and interventional embolization .